Dresden MDS Registry With an Accompanying Biomaterial Collection

NCT07561385 | Not Yet Recruiting

• 1 other identifier: Dresdner MDS-Register
• Study Type: observational
• Target: 500
• Locations: 1 country
• Sites: 1

Brief Summary

A registry for the study of the epidemiology, clinical course, and progression of myelodysplastic neoplasms (MDS), myelodysplastic/myeloproliferative neoplasms (MDS/MPN overlap syndromes), and their precursor syndromes (CHIP, CCUS)

Conditions

MDS (Myelodysplastic Syndrome); CHIP; CCUS Clonal Cytopenia of Undetermined Significance; MDS/Myeloproliferative Neoplasm (MPN) Overlap Syndrome

Outcome Measures

Primary Outcomes (1)

• Collection of epidemiological data on MDS, MDS/MPN overlap syndromes and their precursor syndromes (CHIP, CCUS)

  10 Years

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Diagnosis of myelodysplastic syndrome (MDS), MDS/MPN overlap syndrome, or evidence of a myelodysplastic precursor syndrome, defined as clonal hematopoiesis without cytopenia (clonal hematopoiesis of indeterminate potential, CHIP) or clonal hematopoiesis with cytopenia (clonal cytopenia of undetermined significance, CCUS) according to current WHO criteria

You may qualify if:

• Diagnosis of myelodysplastic syndrome (MDS), MDS/MPN overlap syndrome or evidence of myelodysplastic precursor syndrome, defined as clonal haematopoiesis without cytopenia (clonal haematopoiesis of indeterminate potential, CHIP) or clonal haematopoiesis with cytopenia (clonal cytopenia of undetermined significance, CCUS) in accordance with current WHO criteria
• Age ≥18 years
• Submission of a signed consent form for participation in the MDS Registry

Sponsors & Collaborators

• Technische Universität Dresden: lead

Study Sites (1)

Universitätsklinikum Carl Gustav Carus Dresden

Dresden, 01307, Germany

Location

MeSH Terms

Conditions

Anemia, Refractory, with Excess of Blasts

Condition Hierarchy (Ancestors)

Anemia, Refractory; Anemia; Hematologic Diseases; Hemic and Lymphatic Diseases; Myelodysplastic Syndromes; Bone Marrow Diseases

Central Study Contacts

Katja Sockel, Dr. med.

CONTACT

+493514580; Katja.Sockel@ukdd.de

Ekaterina Balaian, Dr. med.

CONTACT

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: PROSPECTIVE
• Target Duration: 5 Years
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: April 20, 2026
• First Posted: May 1, 2026
• Study Start (Estimated): June 1, 2026
• Primary Completion (Estimated): June 1, 2036
• Study Completion (Estimated): June 1, 2036
• Last Updated: May 1, 2026

Record last verified: 2026-04

Locations

DE (1)