Risk Factors and Predictive Model for Inflammatory Polyps in Ureteral Stones

NCT07559721 | Recruiting

• 1 other identifier: JLU-FH-2026-UROLITH-001
• Study Type: observational
• Target: 300
• Locations: 1 country
• Sites: 1

Brief Summary

This is a single-center, observational study including a retrospective cohort and a prospective validation cohort. The study aims to identify independent risk factors for inflammatory ureteral polyps in patients with ureteral calculi and develop a preoperative predictive model. The retrospective part will analyze clinical and imaging data of patients treated at the First Hospital of Jilin University between 2018 and 2025. The prospective part is currently recruiting participants to validate the model. The primary outcome is the intraoperative diagnosis of inflammatory ureteral polyps.

Conditions

Ureteral Calculi

Outcome Measures

Primary Outcomes (1)

• Intraoperative diagnosis of inflammatory ureteral polyps

  The primary outcome is the presence or absence of inflammatory ureteral polyps confirmed by intraoperative pathology or direct visualization during ureteroscopy.

  At the time of ureteroscopic surgery

Study Arms (2)

Retrospective Cohort

This cohort includes patients with ureteral calculi who underwent treatment between 2018 and 2025 at the First Hospital of Jilin University. Clinical and imaging data will be analyzed to identify risk factors for inflammatory ureteral polyps.

Prospective Validation Cohort

This prospective cohort is currently recruiting patients with ureteral calculi to validate the predictive model developed from the retrospective data.

Eligibility Criteria

• Age: 18 Years - 80 Years
• Sex: all
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The study population includes adult patients with ureteral calculi who underwent ureteroscopic treatment at the First Hospital of Jilin University. The retrospective cohort includes patients treated between 2018 and 2025, and the prospective cohort is recruiting new patients for validation.

You may qualify if:

• Patients aged 18 years or older undergoing ureteroscopic surgery for ureteral calculi at the First Hospital of Jilin University.
• Complete clinical and imaging data available.

You may not qualify if:

• Patients with bilateral ureteral calculi.
• Patients with preoperative nephrostomy or indwelling ureteral stent.
• Patients with a history of ureteral or bladder cancer.
• Patients with congenital ureteral anomalies or previous ureteral surgery.
• Patients with severe coagulation disorders or contraindications to ureteroscopy.
• Patients unable to provide informed consent.

Sponsors & Collaborators

• The First Hospital of Jilin University: lead

Study Sites (1)

The First Hospital of Jilin University

Changchun, Jilin, 130021, China

RECRUITING

MeSH Terms

Conditions

Ureteral Calculi

Condition Hierarchy (Ancestors)

Ureterolithiasis; Ureteral Diseases; Urologic Diseases; Female Urogenital Diseases; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Urolithiasis; Urinary Calculi; Male Urogenital Diseases; Calculi; Pathological Conditions, Anatomical; Pathological Conditions, Signs and Symptoms

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: April 24, 2026
• First Posted: April 30, 2026
• Study Start: March 1, 2026
• Primary Completion (Estimated): February 1, 2027
• Study Completion (Estimated): February 1, 2027
• Last Updated: April 30, 2026

Record last verified: 2026-04

Locations

CN (1)