NCT07557264

Brief Summary

This study evaluates the effectiveness of a 3-month video-based lifestyle intervention, focused on promoting healthy lifestyle habits (healthy eating and increased physical activity), on adults with type 2 diabetes mellitus (DM2). Participants will be randomly allocated to receive the intervention either delivered by their own physician (experimental group) or by a physician unknown to them (control group). Assessment will include sociodemographic variables, glycated hemoglobin / HbA1c (primary outcome), body mass index, blood pressure, glycemic and lipid metabolism variables, physical activity level, adherence to the Mediterranean diet, therapeutic alliance, and health-related quality of life. The randomization process will be stratified according to HbA1c, therapeutic alliance, age, and sex.

Trial Health

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Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
156

participants targeted

Target at P50-P75 for not_applicable diabetes-mellitus-type-2

Timeline
8mo left

Started Sep 2026

Shorter than P25 for not_applicable diabetes-mellitus-type-2

Geographic Reach
1 country

1 active site

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

April 22, 2026

Completed
7 days until next milestone

First Posted

Study publicly available on registry

April 29, 2026

Completed
4 months until next milestone

Study Start

First participant enrolled

September 1, 2026

Expected
6 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2027

2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

May 1, 2027

Last Updated

April 29, 2026

Status Verified

April 1, 2026

Enrollment Period

6 months

First QC Date

April 22, 2026

Last Update Submit

April 22, 2026

Conditions

Outcome Measures

Primary Outcomes (1)

  • Glycated Hemoglobin (HbA1c)

    HbA1c (%) will be used as the primary measure of glycemic control. It reflects average blood glucose levels over the previous 2-3 months and will be obtained from venous blood samples analyzed in routine clinical laboratories.

    Baseline (pre-intervention) and 3 months (post-intervention)

Secondary Outcomes (7)

  • Body Mass Index (BMI)

    Baseline and 3 months

  • Blood Pressure (Systolic and Diastolic)

    Baseline and 3 months

  • Lipid Profile

    Baseline and 3 months

  • Physical Activity Level (IPAQ-SF)

    Baseline and 3 months

  • Adherence to Mediterranean Diet (MEDAS)

    Baseline and 3 months

  • +2 more secondary outcomes

Study Arms (2)

Experimental: Own Physician Group

EXPERIMENTAL

Participants will receive a 3-month video-based lifestyle intervention including audiovisual counseling on healthy eating, physical activity, strength training, and psychological strategies. Content will be delivered by the participant's own physician.

Behavioral: Video-based lifestyle intervention (own physician)

Active Comparator: Unknown Physician Group

ACTIVE COMPARATOR

Participants will receive the same 3 month video-based lifestyle intervention, with identical content delivered by physicians unknown to the participants.

Behavioral: Video-based lifestyle intervention (unknown physician)

Interventions

The experimental group will receive the video-based lifestyle intervention delivered by their own physician, while the control group will receive identical content delivered by physicians unknown to the participants. The intervention consists of structured multimedia modules focusing on nutrition, physical activity, strength exercise, and psychological strategies to support behavior change.

Experimental: Own Physician Group

The experimental group will receive the video-based lifestyle intervention delivered by their own physician, while the control group will receive identical content delivered by physicians unknown to the participants. The intervention consists of structured multimedia modules focusing on nutrition, physical activity, strength exercise, and psychological strategies to support behavior change.

Active Comparator: Unknown Physician Group

Eligibility Criteria

Age18 Years - 65 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Adults aged 18-65 years
  • Diagnosis of type 2 diabetes mellitus
  • Under medical follow-up in participating centers
  • Access to the internet and a smartphone
  • Ability to provide informed consent

You may not qualify if:

  • Pregnancy
  • Type 1 diabetes or other specific forms of diabetes
  • Severe acute or unstable medical condition
  • Contraindication to diet or exercise
  • Severe psychiatric disorder
  • Eating disorder
  • Physical disability limiting physical activity
  • Participation in another structured weight-loss or lifestyle program
  • No medical visit in the last 2 years

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Juan Fco. Lisón. City: Valencia (Spain)

Valencia, Spain

Location

MeSH Terms

Conditions

Diabetes Mellitus, Type 2Motor Activity

Condition Hierarchy (Ancestors)

Diabetes MellitusGlucose Metabolism DisordersMetabolic DiseasesNutritional and Metabolic DiseasesEndocrine System DiseasesBehavior

Central Study Contacts

Juan Francisco Lisón

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

April 22, 2026

First Posted

April 29, 2026

Study Start (Estimated)

September 1, 2026

Primary Completion (Estimated)

March 1, 2027

Study Completion (Estimated)

May 1, 2027

Last Updated

April 29, 2026

Record last verified: 2026-04

Locations