NCT07555197

Brief Summary

This study examines how seafood consumption, social changes, and climate change affect the nutrition and well-being of adolescent girls in south-western Bangladesh. Many adolescent girls face poor nutrition, early marriage, and limited access to adequate diets. Adolescent girls have high nutritional needs due to growth and potential early motherhood. Seafood, including fish, shrimp, and prawns, provides important nutrients such as omega-3 fatty acids, but little is known about how its consumption relates to nutritional status in this population. The study will collect new data from adolescent girls in the same area as a 2017 study (IMMANA study), assessing dietary pattern, nutritional status, socioeconomic conditions, and female autonomy. It will also explore how climate change affects household food access and nutrition to provide policies linking food systems and public health.

Trial Health

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Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
300

participants targeted

Target at P75+ for all trials

Timeline
8mo left

Started Apr 2026

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress5%
Apr 2026Dec 2026

First Submitted

Initial submission to the registry

April 16, 2026

Completed
9 days until next milestone

Study Start

First participant enrolled

April 25, 2026

Completed
4 days until next milestone

First Posted

Study publicly available on registry

April 29, 2026

Completed
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 10, 2026

Expected
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 15, 2026

Last Updated

May 6, 2026

Status Verified

August 1, 2025

Enrollment Period

5 months

First QC Date

April 16, 2026

Last Update Submit

April 30, 2026

Conditions

Keywords

Adolescent nutritionAquacultureClimate changeFish consumptionFemale autonomyNutritional status

Outcome Measures

Primary Outcomes (6)

  • Omega-3 status

    Docosahexaenoic acid (DHA) in whole blood (% of total fatty acid)

    One sampling point between April and August 2026

  • Omega-3 status

    Eicosapentaenoic acid (EPA) in whole blood (% of total fatty acid)

    One sampling point between April and August 2026

  • Micronutrient status

    Serum levels of vitamin D (total 25-hydroxyvitamin D), nmol/L

    One sampling point between April and August 2026

  • Micronutrient status

    Serum levels of Ferritin (µg/L)

    One sampling point between April and August 2026

  • Micronutrient status

    serum levels of retinol (μmol/L)

    One sampling point between April and August 2026

  • Micronutrient status

    Serum levels of vitamin B12 (ng/L)

    One sampling point between April and August 2026

Secondary Outcomes (5)

  • Inflammation status

    One sampling point between April and August 2026

  • Inflammation status

    One sampling point between April and August 2026

  • Nutritional status

    One measurement between April and August 2026

  • Nutritional status

    One measurement between April and August 2026

  • Micronutrient status

    Between April and August

Other Outcomes (3)

  • Fish consumption pattern over the last seven days

    Between April and August 2026

  • Dietary pattern assessment

    Between April 2026 to August 2026

  • Female autonomy

    Between April 2026 to August 2026

Study Arms (1)

Cross-sectional assessment of adolescent girls

Adolescent girls' diet, nutritional status, socioeconomic conditions, and female autonomy, and climate change impacts on food access and nutrition will be assessed in two seasons.

Other: Assess natural behavior

Interventions

No intervention

Also known as: No intervention
Cross-sectional assessment of adolescent girls

Eligibility Criteria

Age12 Years - 17 Years
Sexfemale
Healthy VolunteersYes
Age GroupsChild (0-17)
Sampling MethodProbability Sample
Study Population

The study will recruit 300 adolescent girls aged 12-16 years from the same study area as the 2017 IMMANA study. This will allow comparison of changes over the past 10 years in dietary patterns, nutritional status, fish consumption, and micronutrient status including blood levels of omega-3 fatty acids.

You may qualify if:

  • Adolescent girls aged between 12-16 years
  • Residing in the same study area as the 2017 IMMANA study
  • Willing to participate and provide informed consent

You may not qualify if:

  • Any health condition that may affect anthropometric measurements
  • Severe illness that may interfere with physical or biochemical assessments

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

International Centre for Diarrhoeal Disease Research, Bangladesh (icddr, b)

Dhaka, Capital Region, 1000, Bangladesh

Location

Related Publications (2)

  • Grieve, E., Mamun, A. A., De Roos, B., Barman, B. K., Ara, G., Roos, N., ... & Little, D. C. (2023). Adolescent girls in aquaculture ecozones at risk of nutrient deficiency in Bangladesh development and validation of an integrated metric. BMC Public Health, 23(1), 405.

    BACKGROUND
  • Ara, G., Little, DC, Mamun, AA, De Roos, B., Grieve, E., Khanam, M., ... & Roos, N. (2023). Factors affecting the micronutrient status of adolescent girls living in complex agro-aquatic ecological zones of Bangladesh. Scientific Reports , 13 (1), 6631.

    BACKGROUND

Related Links

Study Officials

  • Gulshan Ara, PhD

    International Centre for Diarrhoeal Disease Research, Bangladesh

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Nanna Roos, PhD

CONTACT

Study Design

Study Type
observational
Observational Model
OTHER
Time Perspective
CROSS SECTIONAL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

April 16, 2026

First Posted

April 29, 2026

Study Start

April 25, 2026

Primary Completion (Estimated)

September 10, 2026

Study Completion (Estimated)

December 15, 2026

Last Updated

May 6, 2026

Record last verified: 2025-08

Data Sharing

IPD Sharing
Will not share

As per the ethical approval, participant data will not be shared publicly. Anonymised data can be shared by study coordinator upon reasonable request.

Locations