Remote Monitoring and Symptom Management Digital Application

NCT07553572 | Recruiting

• 1 other identifier: 25-739
• Study Type: interventional
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

The goal of this clinical trial is to learn if an artificial intelligence phone application called ASSIST can help patients receiving cancer treatment. The main question\[s\] it aims to answer are: Is ASSIST feasible for patients (meaning can it be used by patients)? Is ASSIST acceptable to patients (meaning do patients like it)? Researchers will compare the ASSIST phone application to see how it compares to usual clinical care. Participants on the ASSIST arm will use the ASSIST phone application for 12 weeks, and participants in both groups will complete surveys.

Conditions

Lymphoma; Colorectal Cancer; Breast Cancer (Locally Advanced or Metastatic)

Outcome Measures

Primary Outcomes (2)

• Recruitment Rates

  We will deem the intervention feasible if recruitment rates achieve ≥ 60% of eligible patients

  From enrollment to end of intervention at 12 weeks

• Percentage of participants using the digital application once per week in at least 7/12 weeks

  The intervention will be feasible if among those enrolled and randomized to the intervention arm, ≥ 60% use ASSIST once per week in at least 7/12 weeks.

  From enrollment to end of intervention at 12 weeks

Secondary Outcomes (1)

• Acceptability

  From enrollment to the end of the intervention at 12 weeks

Study Arms (2)

ASSIST phone application arm

EXPERIMENTAL

The intervention consists of a smartphone-based application that provides personalized support using AI during cancer treatment. Patients will also receive standard care from their oncology team, including routine symptom management and supportive care measures.

Other: ASSIST phone application

Usual Care

NO INTERVENTION

Patients in the usual care group will receive standard care from their oncology team, including routine symptom management and supportive care measures.

Interventions

ASSIST phone application OTHER

The intervention consists of a smartphone-based application that provides personalized support using AI during cancer treatment. Patients will also receive standard care from their oncology team, including routine symptom management and supportive care measures.

ASSIST phone application arm

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Age 18 years or older
• Ability to understand English
• About to begin definitive systemic treatment (or within 4 weeks of beginning treatment) based upon the oncology treatment intent form for a new diagnosis of breast cancer, colorectal cancer, or lymphoma.
• Expected treatment duration of at least 12 weeks
• Own or willing to receive a smartphone

You may not qualify if:

• Cognitive impairment that would interfere with ability to use smartphone application (as assessed by their attending physician)
• Visual or motor impairment that would prevent smartphone use
• Expected survival less than 3 months

Sponsors & Collaborators

• Patrick C. Johnson, MD: lead

Study Sites (1)

Massachusetts General Hospital

Boston, Massachusetts, 02114, United States

RECRUITING

MeSH Terms

Conditions

Breast Neoplasms; Neoplasm Metastasis; Lymphoma; Colorectal Neoplasms

Condition Hierarchy (Ancestors)

Neoplasms by Site; Neoplasms; Breast Diseases; Skin Diseases; Skin and Connective Tissue Diseases; Neoplastic Processes; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Neoplasms by Histologic Type; Lymphoproliferative Disorders; Lymphatic Diseases; Hemic and Lymphatic Diseases; Immunoproliferative Disorders; Immune System Diseases; Intestinal Neoplasms; Gastrointestinal Neoplasms; Digestive System Neoplasms; Digestive System Diseases; Gastrointestinal Diseases; Colonic Diseases; Intestinal Diseases; Rectal Diseases

Central Study Contacts

Patrick C Johnson, MD

CONTACT

6177244000; pcjohnson@mgh.harvard.edu

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: SUPPORTIVE CARE
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Assistant Professor of Medicine

Study Record Dates

• First Submitted: April 14, 2026
• First Posted: April 28, 2026
• Study Start: April 14, 2026
• Primary Completion (Estimated): November 30, 2026
• Study Completion (Estimated): March 31, 2027
• Last Updated: April 28, 2026

Record last verified: 2026-04

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)