NCT07551128

Brief Summary

Dental implants have revolutionized oral rehabilitation for partially edentulous patients. Recent advances in implant design and surface treatments have prompted the investigation of early loading methods, which aim to minimize treatment time while maintaining success rates.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
22

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Dec 2024

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

December 1, 2024

Completed
7 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 28, 2025

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 28, 2025

Completed
10 months until next milestone

First Submitted

Initial submission to the registry

April 18, 2026

Completed
6 days until next milestone

First Posted

Study publicly available on registry

April 24, 2026

Completed
Last Updated

April 24, 2026

Status Verified

April 1, 2026

Enrollment Period

7 months

First QC Date

April 18, 2026

Last Update Submit

April 18, 2026

Conditions

Dental Implant Stability

Outcome Measures

Primary Outcomes (1)

  • Change in implant stability

    Ostell device was used for implant stability assessment.

    baseline, 2 ,4 ,12 ,24 weeks

Secondary Outcomes (2)

  • Change in bone gain

    12 and 24-weeks

  • Change in density

    12 and 24-weeks

Study Arms (2)

Test Group

EXPERIMENTAL
Other: Early implant loading

Conventional

ACTIVE COMPARATOR
Other: Delayed loading

Interventions

Early implant loadingOTHER

Early Loading at 4 weeks, a screw-retained definitive restoration was delivered using standard prosthetic procedures.

Test Group
Delayed loadingOTHER

Conventional Delayed Loading at 24 weeks, the definitive restoration was delivered using standard prosthetic procedures.

Conventional

Eligibility Criteria

Age25 Years - 60 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Adequate bone volume allowing implant placement without grafting (width \> 6 mm, height \> 10 mm)
  • bone quality classified as D2

You may not qualify if:

  • uncontrolled systemic diseases
  • active infection or untreated periodontal disease
  • heavy smoking (\>10 cigarettes/day)
  • parafunctional habits
  • inability to attend follow-up visits

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Outpatient Clinic of Oral and Maxillofacial Surgery Department, Faculty of Dentistry, Alexandria University, Egypt

Alexandria, Azarita, 00203, Egypt

Location

MeSH Terms

Interventions

Immediate Dental Implant Loading

Intervention Hierarchy (Ancestors)

Dental Implantation, EndosseousDental ImplantationOral Surgical Procedures, PreprostheticOral Surgical ProceduresSurgical Procedures, OperativeProsthesis ImplantationDentistryProsthodontics

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

April 18, 2026

First Posted

April 24, 2026

Study Start

December 1, 2024

Primary Completion

June 28, 2025

Study Completion

June 28, 2025

Last Updated

April 24, 2026

Record last verified: 2026-04

Locations

EG(1)