NCT07551011

Brief Summary

This trial aims to evaluate the effectiveness of a Behavioral Modification Working (BMW) Toolkit in improving glycemic control and blood pressure among pregnant women diagnosed with both GDM and PIH.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
220

participants targeted

Target at P75+ for not_applicable

Timeline
8mo left

Started Apr 2026

Shorter than P25 for not_applicable

Geographic Reach
1 country

2 active sites

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress6%
Apr 2026Jan 2027

First Submitted

Initial submission to the registry

April 19, 2026

Completed
2 days until next milestone

Study Start

First participant enrolled

April 21, 2026

Completed
3 days until next milestone

First Posted

Study publicly available on registry

April 24, 2026

Completed
8 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 25, 2026

Expected
21 days until next milestone

Study Completion

Last participant's last visit for all outcomes

January 15, 2027

Last Updated

April 30, 2026

Status Verified

April 1, 2026

Enrollment Period

8 months

First QC Date

April 19, 2026

Last Update Submit

April 24, 2026

Conditions

Keywords

Gestational Diabetes MellitusPregnancy Induced HypertensionMaternal healthChildbirthRisk FactorsinterventionBMW ToolkitDietary habitsPhysical activitysleep pattern

Outcome Measures

Primary Outcomes (2)

  • Fasting Blood Glucose

    Fasting blood glucose concentration (mg/dL or mmol/L, according to site laboratory standard) will be measured at baseline and at follow-up. The outcome measure is the change from baseline to 40 weeks gestation, compared between study groups.

    Baseline and 40 weeks gestation

  • Blood Pressure

    Systolic and diastolic blood pressure (mmHg) measured at baseline and follow-up. Outcome is change from baseline to 36 weeks gestation compared between study groups.

    Baseline and 36 weeks gestation

Study Arms (2)

BMW Toolkit + Routine Antenatal Care

EXPERIMENTAL

Participants receive the Behavioral Modification Working (BMW) Toolkit in addition to routine antenatal care. The intervention includes 7-8 structured sessions delivered by a trained health educator focusing on dietary modification, physical activity, sleep hygiene, and self-care practices during pregnancy.

Behavioral: Behavioral Modification Working (BMW) Toolkit

Routine Antenatal Care Alone

ACTIVE COMPARATOR

Participants receive routine antenatal care according to standard hospital practice for management of gestational diabetes mellitus and pregnancy-induced hypertension without the BMW Toolkit intervention.

Other: Routine Antenatal Care

Interventions

Structured behavioral intervention consisting of 7-8 sessions delivered by a trained health educator focusing on dietary modification, physical activity promotion, sleep hygiene, and self-care practices for pregnant women with gestational diabetes mellitus and pregnancy-induced hypertension, provided in addition to routine antenatal care.

Also known as: BMW Toolkit
BMW Toolkit + Routine Antenatal Care

Standard antenatal care provided according to hospital protocol for gestational diabetes mellitus and pregnancy-induced hypertension.

Routine Antenatal Care Alone

Eligibility Criteria

Age15 Years - 49 Years
Sexfemale
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64)

You may qualify if:

  • Pregnant women aged 15-49 years.
  • Gestational age between 16 and 20 weeks at enrolment.
  • Diagnosed with both gestational diabetes mellitus (GDM) and pregnancy-induced hypertension (PIH).
  • At least one prior antenatal visit at the study site.

You may not qualify if:

  • Pre-existing diabetes mellitus or chronic hypertension prior to pregnancy.
  • Pre-existing renal disease, thyroid disease, or major hematological disorders.
  • Multiple pregnancy (e.g., twins, triplets).
  • Severe psychiatric illness.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Shaikh Zayed Hospital

Lahore, Punjab Province, 54000, Pakistan

RECRUITING

Sir Ganga Ram Hospital

Lahore, Punjab Province, 54000, Pakistan

RECRUITING

Related Publications (3)

  • Lin C, Guan Q, Su B, Lin H, Xu Y, Wu Q, Ge L. Enhancing gestational diabetes mellitus education: a randomized controlled trial of King's theory and FMEA-PDCA integration for improved patient outcomes. BMC Pregnancy Childbirth. 2025 Oct 11;25(1):1070. doi: 10.1186/s12884-025-07932-2.

    PMID: 41076518BACKGROUND
  • Phudphad T, Teravecharoenchai S, Khemtong P, Suksatan W. Examining the Impact of a Behavior Modification Program on Disease Prevention Behaviors among Individuals at Risk of Diabetes: A Quasi-Experimental Investigation. Eur J Investig Health Psychol Educ. 2024 Jul 6;14(7):1969-1980. doi: 10.3390/ejihpe14070131.

    PMID: 39056646BACKGROUND
  • Dang NT, Le HM, Nguyen A, Glode PC, Vinter CA, Nielsen J, Nguyen KD, Gammeltoft TM, Linde DS. Self-care interventions among women with gestational diabetes mellitus in low and middle-income countries: a scoping review. Syst Rev. 2025 Feb 27;14(1):50. doi: 10.1186/s13643-025-02790-7.

    PMID: 40016820BACKGROUND

MeSH Terms

Conditions

Hypertension, Pregnancy-InducedDiabetes, GestationalFeeding BehaviorMotor Activity

Condition Hierarchy (Ancestors)

Pregnancy ComplicationsFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital DiseasesHypertensionVascular DiseasesCardiovascular DiseasesDiabetes MellitusGlucose Metabolism DisordersMetabolic DiseasesNutritional and Metabolic DiseasesEndocrine System DiseasesBehavior, AnimalBehavior

Central Study Contacts

Assia Riaz, PhD Public Health

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Masking Details
Due to the nature of the behavioral intervention, participants and care providers cannot be blinded. Outcome assessors/data analysts may be blinded where feasible.
Purpose
TREATMENT
Intervention Model
PARALLEL
Model Details: Two-arm parallel randomized controlled trial comparing BMW Toolkit + routine care versus routine antenatal care alone
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

April 19, 2026

First Posted

April 24, 2026

Study Start

April 21, 2026

Primary Completion (Estimated)

December 25, 2026

Study Completion (Estimated)

January 15, 2027

Last Updated

April 30, 2026

Record last verified: 2026-04

Data Sharing

IPD Sharing
Will share

De-identified individual participant data (IPD) underlying the results reported in the primary and secondary outcome analyses will be made available to researchers upon reasonable request. Shared data will include demographic, clinical (fasting blood glucose, systolic/diastolic blood pressure), maternal outcomes (e.g., preeclampsia, mode of delivery), neonatal outcomes (e.g., birth weight, gestational age), and knowledge/self-care practice scores. The study protocol, statistical analysis plan, and informed consent form will also be shared.

Shared Documents
STUDY PROTOCOL, SAP, ICF, CSR, ANALYTIC CODE
Time Frame
Data will become available starting 6 months after publication of the primary trial results and will remain available for 5 years.
Access Criteria
Access will be granted to researchers who submit a methodologically sound proposal with a clear research question, approved by the principal investigator and the Punjab University Institutional Ethics Review Board. A signed data access agreement ensuring confidentiality and appropriate use is required.

Locations