Influence of Residual Bone Height on Marginal Bone Loss Around Implants Following Lateral Sinus Floor Augmentation With Deproteinized Bovine Bone Mineral

NCT07550491 | Completed

• 1 other identifier: FMD-SF192
• Study Type: observational
• Target: 142
• Locations: 1 country
• Sites: 1

Brief Summary

Data collection will be done on all patients who underwent a lateral maxillary sinus floor augmentation in the Faculty of Dental Medicine, both in the Periodontology Department and in the Oral Surgery Department. Pre-surgical residual bone height will be measured on patients with a preoperative CBCT, and marginal bone loss will be measured in patients with a postoperative periapical radiograph that dates at least 3 years after implant placement. In contrast to other studies who only associated between the presurgical residual bone height and implant survival / success rate, this study design takes a more in depth approach and measures the exact marginal bone loss on each implant. In addition, other factors will be taken into consideration (implant type, smoking status, diabetes status) to eliminate any confounding factors.

Conditions

Implant Type; Smoking; Diabetes; Marginal Bone Loss; Residual Bone Height

Keywords

Alveolar bone loss; bone substitutes; dental implant; diabetes mellitus; sinus floor augmentation; smoking

Outcome Measures

Primary Outcomes (1)

• Marginal Bone Loss

  mesial and distal marginal bone loss were calculated from the implant platform to the first bone to implant contact

  at least 3 years after implant placement

Study Arms (2)

Grafted Bone

residual bone height \< 2mm

Procedure: sinus lift using DBBM

Native Bone

residual bone height \> 2mm

Procedure: sinus lift using DBBM

Interventions

sinus lift using DBBM PROCEDURE

Sinus lift was performed to the patients, then after 9 months dental implants were placed.

Grafted Bone; Native Bone

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients from the Faculty of Dental Medicine at Saint Joseph University of Beirut who underwent a lateral maxillary sinus floor augmentation

You may qualify if:

• All patients who underwent a lateral maxillary sinus floor augmentation using deproteinated bovine bone matrix (DBBM) at the faculty before 2022.
• Patients with pre-operative CBCT.
• Patients with no visible sinus infection in the pre-operative CBCT.

You may not qualify if:

• Patients who do not have a pre-operative CBCT.
• Patients who do not have a post-operative orthogonal periapical radiograph that dates at least 3 years after implant placement.
• Presence of inflammatory lesions at the surgical site (eg, sinusitis as assessed by CBCT).
• Cases with sinus perforation.
• History of radiation therapy in the head/neck region.
• Use of bisphosphonates

Sponsors & Collaborators

• Saint-Joseph University: lead

Study Sites (1)

Saint Joseph University of Beirut

Beirut, Lebanon

Location

Related Publications (10)

• Albrektsson T, Zarb G, Worthington P, Eriksson AR. The long-term efficacy of currently used dental implants: a review and proposed criteria of success. Int J Oral Maxillofac Implants. 1986 Summer;1(1):11-25. No abstract available.

  PMID: 3527955 BACKGROUND

• Jamcoski VH, Faot F, Marcello-Machado RM, Melo ACM, Fontao FNGK. 15-Year Retrospective Study on the Success Rate of Maxillary Sinus Augmentation and Implants: Influence of Bone Substitute Type, Presurgical Bone Height, and Membrane Perforation during Sinus Lift. Biomed Res Int. 2023 Feb 20;2023:9144661. doi: 10.1155/2023/9144661. eCollection 2023.

  PMID: 36860810 BACKGROUND

• Park WB, Kang KL, Han JY. Factors influencing long-term survival rates of implants placed simultaneously with lateral maxillary sinus floor augmentation: A 6- to 20-year retrospective study. Clin Oral Implants Res. 2019 Oct;30(10):977-988. doi: 10.1111/clr.13505. Epub 2019 Aug 1.

  PMID: 31306519 BACKGROUND

• Rios HF, Avila G, Galindo P, Bratu E, Wang HL. The influence of remaining alveolar bone upon lateral window sinus augmentation implant survival. Implant Dent. 2009 Oct;18(5):402-12. doi: 10.1097/ID.0b013e3181b4af93.

  PMID: 22129958 BACKGROUND

• Galindo-Moreno P, Fernandez-Jimenez A, O'Valle F, Silvestre FJ, Sanchez-Fernandez E, Monje A, Catena A. Marginal bone loss in implants placed in grafted maxillary sinus. Clin Implant Dent Relat Res. 2015 Apr;17(2):373-83. doi: 10.1111/cid.12092. Epub 2013 May 28.

  PMID: 23714301 BACKGROUND

• Del Fabbro M, Wallace SS, Testori T. Long-term implant survival in the grafted maxillary sinus: a systematic review. Int J Periodontics Restorative Dent. 2013 Nov-Dec;33(6):773-83. doi: 10.11607/prd.1288.

  PMID: 24116362 BACKGROUND

• Beretta M, Poli PP, Grossi GB, Pieroni S, Maiorana C. Long-term survival rate of implants placed in conjunction with 246 sinus floor elevation procedures: results of a 15-year retrospective study. J Dent. 2015 Jan;43(1):78-86. doi: 10.1016/j.jdent.2014.08.006. Epub 2014 Aug 20.

  PMID: 25150106 BACKGROUND

• Tatum H Jr. Maxillary and sinus implant reconstructions. Dent Clin North Am. 1986 Apr;30(2):207-29.

  PMID: 3516738 BACKGROUND

• Boyne PJ, James RA. Grafting of the maxillary sinus floor with autogenous marrow and bone. J Oral Surg. 1980 Aug;38(8):613-6. No abstract available.

  PMID: 6993637 BACKGROUND

• Buser D, Dula K, Hess D, Hirt HP, Belser UC. Localized ridge augmentation with autografts and barrier membranes. Periodontol 2000. 1999 Feb;19:151-63. doi: 10.1111/j.1600-0757.1999.tb00153.x. No abstract available.

  PMID: 10321222 BACKGROUND

MeSH Terms

Conditions

Smoking; Diabetes Mellitus; Alveolar Bone Loss

Condition Hierarchy (Ancestors)

Behavior; Glucose Metabolism Disorders; Metabolic Diseases; Nutritional and Metabolic Diseases; Endocrine System Diseases; Bone Resorption; Bone Diseases; Musculoskeletal Diseases; Periodontal Atrophy; Periodontal Diseases; Mouth Diseases; Stomatognathic Diseases

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: April 19, 2026
• First Posted: April 24, 2026
• Study Start: January 1, 2026
• Primary Completion: April 17, 2026
• Study Completion: April 17, 2026
• Last Updated: April 30, 2026

Record last verified: 2026-04

Data Sharing

• IPD Sharing: Will share
• Shared Documents: STUDY PROTOCOL

Locations

LE (1)