IVC Collapsibility Index in Lumbar Stabilization Surgery

NCT07549165 | Recruiting DMC

• 1 other identifier: 10496660-2026/25031
• Study Type: observational
• Target: 128
• Locations: 1 country
• Sites: 2

Brief Summary

This study aims to evaluate perioperative hemodynamic changes using the inferior vena cava (IVC) collapsibility index in patients undergoing lumbar stabilization surgery under general anesthesia. The IVC diameter and collapsibility index will be measured using ultrasonography at predefined perioperative time points. Hemodynamic parameters such as blood pressure and heart rate will also be recorded. The study seeks to determine whether the IVC collapsibility index can be used as a non-invasive indicator of intravascular volume status and hemodynamic changes during lumbar spine surgery.

Conditions

Lumbar Spine Surgery; Hemodynamic Changes; Intravascular Volume Status

Keywords

Inferior Vena Cava • IVC Collapsibility Index • Lumbar Stabilization Surgery • Hemodynamic Monitoring

Outcome Measures

Primary Outcomes (1)

• Inferior Vena Cava Collapsibility Index

  The inferior vena cava (IVC) collapsibility index will be measured using ultrasonography at predefined perioperative time points (preoperative period, after induction of general anesthesia, and before extubation) in patients undergoing elective lumbar spine surgery in the prone position.

  Perioperative period (preoperative assessment, after anesthesia induction, and before extubation)

Secondary Outcomes (1)

• Intraoperative Hypotension Incidence

  During the intraoperative period

Study Arms (1)

Patients Undergoing Lumbar Spine Surgery

Adult patients undergoing elective lumbar spine stabilization surgery under general anesthesia in the prone position. Inferior vena cava (IVC) diameter and collapsibility index will be measured using ultrasonography at predefined perioperative time points (preoperative period, after induction of anesthesia, and before extubation). Hemodynamic parameters such as blood pressure and heart rate will also be recorded.

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Adult patients (≥18 years) scheduled for elective lumbar spine stabilization surgery under general anesthesia at Trabzon University Faculty of Medicine Hospital will be included in this study. All participants will be classified as ASA physical status I-II-III and will undergo surgery in the prone position. Inferior vena cava (IVC) diameter and collapsibility index will be measured using ultrasonography at predefined perioperative time points.

You may qualify if:

• Age ≥ 18 years
• Patients classified as ASA physical status I-II-III
• Patients scheduled for elective lumbar spine stabilization surgery under general anesthesia
• Ability to obtain adequate inferior vena cava (IVC) ultrasonographic imaging
• Provision of written informed consent

You may not qualify if:

• Age younger than 18 years
• Emergency surgery
• American Society of Anesthesiologists (ASA) physical status IV
• Patients undergoing revision lumbar stabilization surgery
• Baseline systolic blood pressure \>180 mmHg or \<90 mmHg
• Heart failure with ejection fraction (EF) \<40%
• Pulmonary artery pressure (PAP) \>40 mmHg
• Presence of intra-abdominal mass, ascites, or increased intra-abdominal pressure
• Body mass index (BMI) \>30 kg/m²
• Pregnancy
• Patients with neurological or psychiatric disorders
• Inability to obtain adequate inferior vena cava (IVC) ultrasonographic imaging
• Refusal to provide written informed consent

Sponsors & Collaborators

• Trabzon Kanuni Education and Research Hospital: lead

Study Sites (2)

Trabzon University Faculty of Medicine Kanunı Training and Research Hospital ,Trabzon

Trabzon, 61080, Turkey (Türkiye)

RECRUITING

Trabzon University Faculty of Medicine, Kanuni Training and Research Hospital

Trabzon, 61080, Turkey (Türkiye)

RECRUITING

Related Publications (2)

• Yoon HK, Lee HC, Chung J, Park HP. Predictive Factors for Hypotension Associated With Supine-to-Prone Positional Change in Patients Undergoing Spine Surgery. J Neurosurg Anesthesiol. 2020 Apr;32(2):140-146. doi: 10.1097/ANA.0000000000000565.

  PMID: 30475290 BACKGROUND

• Lee S, Kim DY, Han J, Kim K, You AH, Kang HY, Park SW, Kim MK, Kim JE, Choi JH. Hemodynamic changes in the prone position according to fluid loading after anaesthesia induction in patients undergoing lumbar spine surgery: a randomized, assessor-blind, prospective study. Ann Med. 2024 Dec;56(1):2356645. doi: 10.1080/07853890.2024.2356645. Epub 2024 May 24.

  PMID: 38794845 BACKGROUND

Central Study Contacts

Şeyma Yüksel Ayar, MD

CONTACT

+905395655853; balseymayuksel@hotmail.com

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Araştırma Görevlisi

Study Record Dates

• First Submitted: April 17, 2026
• First Posted: April 23, 2026
• Study Start: February 15, 2026
• Primary Completion: February 15, 2026
• Study Completion (Estimated): July 15, 2026
• Last Updated: April 23, 2026

Record last verified: 2026-04

Data Sharing

• IPD Sharing: Will not share

Locations

TU (2)