Segmental Decompression Versus Wide Decompression With Fixation for Degenerative Lumbar Canal Stenosis

NCT07542054 | Not Yet Recruiting

• 1 other identifier: Lumbar: Seg. vs Wide Decomp
• Study Type: interventional
• Target: 56
• Locations: 0 countries
• Sites: N/A

Brief Summary

The purpose of this study is to compare two different surgical techniques for treating degenerative lumbar canal stenosis, a condition where the lower spinal canal narrows and puts pressure on the spinal nerves. For patients who continue to experience significant back and leg pain after at least three months of non-surgical treatments, surgery is often recommended to relieve the pressure. Currently, there is an ongoing debate among spine surgeons regarding the most effective surgical approach. This study will evaluate and compare the outcomes of two established methods:

1. 1.Segmental Decompression Alone: A procedure focused purely on removing the bone and tissue that is pressing on the spinal nerves.
2. 2.Wide Decompression with Fixation: A more extensive removal of compressive structures, combined with adding spinal hardware (pedicle screws and rods) to stabilize the spine.

Conditions

Degenerative Lumbar Spinal Stenosis

Keywords

Lumbar Canal Stenosis; Degenerative Spine Disease; Neurogenic Claudication; Sciatica; Low Back Pain; Segmental Decompression; Wide Decompression

Outcome Measures

Primary Outcomes (1)

• Functional Recovery as Assessed by the Oswestry Disability Index (ODI)

  Functional disability will be quantified using the Oswestry Disability Index (ODI) questionnaire. The ODI is a validated index scored from 0 to 100, where 0 indicates no disability and 100 indicates maximum possible disability. A decrease in the score from baseline indicates functional improvement and a better surgical outcome.

  Baseline, 3 months, 6 months, and 12 months postoperative

Study Arms (2)

Segmental Decompression Alone

ACTIVE COMPARATOR

Participants in this arm will undergo surgical segmental decompression without spinal fixation for the treatment of symptomatic multilevel degenerative lumbar canal stenosis.

Procedure: Segmental Decompression

Wide Decompression with Fixation

ACTIVE COMPARATOR

Participants in this arm will undergo wide surgical decompression combined with spinal fixation utilizing pedicle screws and rods for the treatment of symptomatic multilevel degenerative lumbar canal stenosis.

Procedure: Wide Decompression with Fixation

Interventions

Segmental Decompression PROCEDURE

A surgical technique involving the targeted removal of compressive structures in the lumbar spine to relieve neurogenic claudication and leg pain, performed without the addition of spinal instrumentation or fusion.

Segmental Decompression Alone

Wide Decompression with Fixation PROCEDURE

A surgical technique that combines extensive decompression of the lumbar canal with spinal instrumentation. This involves the application of pedicle screws and rods across varying segment lengths to provide stabilization to the affected spine.

Wide Decompression with Fixation

Eligibility Criteria

• Age: 40 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Age greater than 40 years
• Both males and females
• Multilevel lumbar canal stenosis with failed routine conservative treatment at least 3 months
• X-ray dynamic views of the lumbar spine showing no evidence of instability

You may not qualify if:

• Age less than 40 years
• Recurrent cases and screw revision cases
• Degenerative scoliosis

Sponsors & Collaborators

• Assiut University: lead

MeSH Terms

Conditions

Sciatica; Low Back Pain

Condition Hierarchy (Ancestors)

Sciatic Neuropathy; Mononeuropathies; Peripheral Nervous System Diseases; Neuromuscular Diseases; Nervous System Diseases; Neuralgia; Pain; Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Back Pain

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NON RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Resident at Neurosurgery Department, Misr University for Science and Technology

Study Record Dates

• First Submitted: April 14, 2026
• First Posted: April 21, 2026
• Study Start: May 1, 2026
• Primary Completion (Estimated): May 1, 2027
• Study Completion (Estimated): June 1, 2027
• Last Updated: April 21, 2026

Record last verified: 2026-04