NCT07538063

Brief Summary

This study compared two educational methods. Participants were assigned to participate in a 360-degree experience or a slideshow presentation. The 360-degree video group included a brain and MS program. The comparison group was given a slideshow presentation with the same information. Participants viewed the 360-degree program or the slideshow presentation only once. The online-based materials consisted of a demographic form (age, gender, race and ethnicity, and name of school), knowledge questionnaires, and an experiential learning scale. Pre-intervention, participants were asked about demographic information, whether they had previous experience with MS, the science classes they completed in high school and college, and their knowledge of the human brain and MS pathophysiology. At both pre- and post-intervention, participants completed the Multiple Sclerosis Magnetic Resonance Imaging Knowledge Questionnaire (MSMRIKQ) and the Multiple Sclerosis Knowledge Questionnaire (MSKQ). At post-intervention, participants completed a lesson experiential questionnaire about their experience viewing either the 360-degree video or the slideshow presentation. Permission to use the three instruments was obtained from their respective copyright holders.

Trial Health

75
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
50

participants targeted

Target at P50-P75 for not_applicable multiple-sclerosis

Timeline
8mo left

Started Jul 2020

Longer than P75 for not_applicable multiple-sclerosis

Geographic Reach
1 country

2 active sites

Status
active not recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress90%
Jul 2020Dec 2026

Study Start

First participant enrolled

July 1, 2020

Completed
4.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2024

Completed
1.3 years until next milestone

First Submitted

Initial submission to the registry

April 12, 2026

Completed
8 days until next milestone

First Posted

Study publicly available on registry

April 20, 2026

Completed
9 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2026

Expected
Last Updated

April 20, 2026

Status Verified

April 1, 2026

Enrollment Period

4.5 years

First QC Date

April 12, 2026

Last Update Submit

April 12, 2026

Conditions

Keywords

Multiple SclerosisInteractive Educational MethodsLearning ExperienceNursing Students

Outcome Measures

Primary Outcomes (1)

  • Learning effectiveness of immersive 360-degree video versus a slideshow presentation

    The learning effectiveness was evaluated by two instruments. Outcomes assessed using the MS Knowledge Questionnaire(MSKQ), the MS Magnetic Resonance Imaging Knowledge Questionnaire(MSMRIKQ). The MSMRIKQ is a 20-item questionnaire16 that assesses knowledge about MS and MRI. Face validity was established on all MSMRIKQ items.24 The Kuder-Richardson 20 (KR-20) reliability estimate for the entire scale was 0.58. The split-half reliability with Spearman-Brown correction for the total scale was 0.60. The MSKQ measures basic knowledge of various MS information domains for both clinical and research uses. The Flesch-Kincaid English reading level is 4.8, indicating low reading difficulty. In creating the MSKQ, Giordano et al. (2009) found that the internal consistency was satisfactory (KR-20 = 0.76), and item-total correlations were above 0.30 for 80% of the items.

    The outcomes assessed immediately after viewing the educational 360 degrees video or the PowerPoint slideshow presentation.

Secondary Outcomes (1)

  • The emotional experience

    The emotional experience was completed immediately after the intervention.

Study Arms (2)

Intervention group - 360-degree educational video

EXPERIMENTAL

The 360-degree video group included a brain and MS program. The immersive activity 360-degree group, included a virtual brain and MS program displayed on an interactive computer screen interface. The 360-degree video allowed learners to manipulate the viewing angle of the video to look around the environment. A 360-degree video on the brain and the pathophysiology of MS displayed on an e-learning platform enabled the students to self-learn through a procedure simulation with real time feedback.

Other: The immersive 360-degree educational video

The slideshow presentation group

ACTIVE COMPARATOR

The slideshow presentation group viewed 12 slides about the brain and MS with content identical to the content of the 360-degree program. The educational content consisted of lessons on how the brain and MS interact and interrelate via neurological network.

Other: The slideshow (PowerPoint) educational presentation

Interventions

The immersive activity, 360-degree group, included a virtual brain and MS program displayed on an interactive computer screen interface. The 360-degree video allowed learners to manipulate the viewing angle of the video to look around the environment. A 360-degree video on the brain and the pathophysiology of MS displayed on an e-learning platform enabled the students to self-learn through a procedure simulation with real time feedback.

Intervention group - 360-degree educational video

The slideshow presentation included 12 slides about the brain and MS with content identical to the content of the 360-degree program. The educational content of the PowerPoint slideshow presentation consisted of lessons on how the brain and MS interact and interrelate via neurological network.

The slideshow presentation group

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Fairfield Univesity Nursing School

Fairfield, Connecticut, 06824, United States

Location

Hunter College

New York, New York, 10006, United States

Location

Related Links

MeSH Terms

Conditions

Multiple Sclerosis

Condition Hierarchy (Ancestors)

Demyelinating Autoimmune Diseases, CNSAutoimmune Diseases of the Nervous SystemNervous System DiseasesDemyelinating DiseasesAutoimmune DiseasesImmune System Diseases

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
OTHER
Intervention Model
PARALLEL
Model Details: This is a longitudian quasi-experimental educational study. This study assigned participants to a 360-degree educational video or a slideshow presentation about the brain and multiple sclerosis to undergraduate students from three universities, Hunter College Nursing School, Mount Sinai Phillips School of Nursing, and Fairfield University. Outcomes assessed using the MS Knowledge Questionnaire (MSKQ), the MS Magnetic Resonance Imaging Knowledge Questionnaire( MSMRIKQ), and a post-lesson experiential questionnaire. The theory of multimedia learning and interest theory guided this study in predicting learning outcomes.
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant Professor

Study Record Dates

First Submitted

April 12, 2026

First Posted

April 20, 2026

Study Start

July 1, 2020

Primary Completion

December 31, 2024

Study Completion (Estimated)

December 31, 2026

Last Updated

April 20, 2026

Record last verified: 2026-04

Data Sharing

IPD Sharing
Will share

Data plan and data collection including instruments will be shared with others.

Shared Documents
STUDY PROTOCOL, SAP, ICF
Time Frame
01/01/2027
Access Criteria
Investigator who are faculty in nursing schools.
More information

Locations