Outcome of Hyaluronic Acid Gel Versus Petroleum Jelly in Treatment of Epistaxis
1 other identifier
interventional
50
0 countries
N/A
Brief Summary
The aim of this study is to compare the efficacy of Hyaluronic Acid Gel with Petroleum Jelly in treatment of epistaxis.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for not_applicable
Started May 2026
Typical duration for not_applicable
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
April 9, 2026
CompletedFirst Posted
Study publicly available on registry
April 15, 2026
CompletedStudy Start
First participant enrolled
May 1, 2026
ExpectedPrimary Completion
Last participant's last visit for primary outcome
April 1, 2028
Study Completion
Last participant's last visit for all outcomes
June 1, 2028
April 15, 2026
April 1, 2026
1.9 years
April 9, 2026
April 9, 2026
Conditions
Outcome Measures
Primary Outcomes (1)
To compare the recurrence rate of epistaxis between the two groups
"Proportion of participants whose epistaxis stops completely within 7 days of treatment application."
14 days
Secondary Outcomes (4)
To assess time to symptom resolution
Within 24 hours
To evaluate mucosal healing (endoscopic findings)
7-14 days
To assess patient comfort and compliance
7 days
To record adverse effects
14 days
Study Arms (2)
Hyaluronic Acid Gel
EXPERIMENTAL"Participants in this group will receive topical hyaluronic acid gel applied to the nasal mucosa for the treatment of epistaxis. The application will be done as per the study protocol, and outcomes will be monitored over the study period."
Petroleum Jelly
EXPERIMENTAL"Participants in this group will receive topical petroleum jelly applied to the nasal mucosa for the treatment of epistaxis. The application will follow the study protocol, and outcomes will be monitored over the study period."
Interventions
"Topical hyaluronic acid gel will be applied to the nasal mucosa of participants for the treatment of epistaxis. The gel will be administered according to the study protocol and frequency, and outcomes will be assessed throughout the study period."
"Topical petroleum jelly will be applied to the nasal mucosa of participants for the treatment of epistaxis. The application will follow the study protocol, and outcomes will be monitored and recorded over the study period."
Eligibility Criteria
You may qualify if:
- Patients with anterior and localized idiopathic epistaxis
You may not qualify if:
- Secondary epistaxis (posttraumatic, postoperative, tumoral).
- Pregnancy.
- Major systemic disease (Blood Disease, Hypertension).
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Related Links
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- STUDY DIRECTOR
Ahmed AbdelAleem AbdelWahab, Prof
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- NON RANDOMIZED
- Masking
- NONE
- Masking Details
- "This is an open-label study; both participants and investigators will be aware of the assigned treatment (Hyaluronic Acid Gel or Petroleum Jelly) due to the nature of the interventions."
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- M.B.B.CH
Study Record Dates
First Submitted
April 9, 2026
First Posted
April 15, 2026
Study Start (Estimated)
May 1, 2026
Primary Completion (Estimated)
April 1, 2028
Study Completion (Estimated)
June 1, 2028
Last Updated
April 15, 2026
Record last verified: 2026-04
Data Sharing
- IPD Sharing
- Will not share