Survey on Physical Activity and Qualify of Life in Fibromuscular Dysplasia

NCT07529691 | Recruiting

• 1 other identifier: 251831
• Study Type: observational
• Target: 2,000
• Locations: 1 country
• Sites: 1

Brief Summary

Fibromuscular dysplasia (FMD) is a disease of the arteries that is not due to plaque build-up or inflammation. While some patients with FMD are health, some may experience heart attacks, strokes, aneurysms or blood vessel dissection/tearing which can be life-threatening. It predominantly impacts women and younger patients. As a result of this diagnosis, many patients are counseled to restrict or avoid certain physical activities out of concern for provoking or worsening vascular complications. There are no guidelines or consensus recommendations regarding appropriate physical activity for patients with FMD. The lack of consensus may lead to confusion for patients and may negatively impact their quality of life. This study will conduct a large, national survey of patients with FMD to assess the type of physical activity restrictions and impact on quality of life and emotional well-being.

Conditions

Fibromuscular Dysplasia of Arteries; Fibromuscular Dysplasia; Spontaneous Coronary Artery Dissection

Keywords

FMD; Fibromuscular dysplasia; SCAD; Exercise; Quality of life

Outcome Measures

Primary Outcomes (1)

• Clinician-Recommended Physical Activity Restrictions

  Prevalence and type of clinician-recommended physical activity restrictions among patients diagnosed with fibromuscular dysplasia (FMD), including aerobic, resistance, and activity-specific limitations.

  Baseline

Secondary Outcomes (3)

• Self-Reported Change in Physical Activity Following Diagnosis

  Baseline

• Emotional Impact of Physical Activity Recommendations

  Baseline

• Physical Impact of Activity Recommendations

  Baseline

Study Arms (1)

Patients with fibromuscular dysplasia

Patients who identify as having a confirmed diagnosis of fibromuscular dysplasia, or patients at Vanderbilt University Medical Center who have a confirmed diagnosis of fibromuscular dysplasia as determined by their provider.

Eligibility Criteria

• Age: 18 Years - 100 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Individuals with a diagnosis of fibromuscular dysplasia

You may qualify if:

• Participants with a diagnosis of fibromuscular dysplasia
• Age range = 18-100 years

You may not qualify if:

• Subjects who have an inability to complete the electronic consent form or electronic survey for any reason
• Subjects who are non-English speaking who cannot read the electronic consent form or electronic survey

Sponsors & Collaborators

• Vanderbilt University Medical Center: lead
• Fibromuscular Dysplasia Society of America: collaborator

Study Sites (1)

Vanderbilt University Medical Center

Nashville, Tennessee, 37232, United States

RECRUITING

MeSH Terms

Conditions

Fibromuscular Dysplasia; Coronary Artery Dissection, Spontaneous; Motor Activity

Condition Hierarchy (Ancestors)

Arterial Occlusive Diseases; Vascular Diseases; Cardiovascular Diseases; Behavior

Study Officials

• Aaron W Aday, MD, MSc

  Vanderbilt University Medical Center

  STUDY CHAIR

Central Study Contacts

Amanda Morrison, MD

CONTACT

615-322-5000; amanda.morrison@vumc.org

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Cardiovascular Medicine Fellow

Study Record Dates

• First Submitted: April 6, 2026
• First Posted: April 14, 2026
• Study Start: April 14, 2026
• Primary Completion (Estimated): April 30, 2027
• Study Completion (Estimated): June 30, 2027
• Last Updated: April 20, 2026

Record last verified: 2026-04

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)