NCT07528469

Brief Summary

Examining the effects of PeptiStrong and protein on muscle function in older adults

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
80

participants targeted

Target at P50-P75 for not_applicable

Timeline
6mo left

Started Apr 2026

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress15%
Apr 2026Oct 2026

First Submitted

Initial submission to the registry

March 30, 2026

Completed
7 days until next milestone

Study Start

First participant enrolled

April 6, 2026

Completed
8 days until next milestone

First Posted

Study publicly available on registry

April 14, 2026

Completed
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 30, 2026

Expected
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

October 30, 2026

Last Updated

May 6, 2026

Status Verified

April 1, 2026

Enrollment Period

4 months

First QC Date

March 30, 2026

Last Update Submit

April 30, 2026

Conditions

Healthy AgeingProtein SupplementationMuscle HealthMuscle FunctionHand Grip StrengthLongevityPeptides

Keywords

Healthy AgingProtein supplementationMuscle functionPhysical performanceLongevityBioactive peptidesHand grip strengthShort performance physical batteryNuritasLiverpool John Moore University

Outcome Measures

Primary Outcomes (1)

  • Hand Grip Strength via hand held dynamometer

    Change from baseline to end of study in grip strength as assessed via hand held dynamometer

    Baseline to Week 4

Secondary Outcomes (10)

  • Chair Stand Test - Part of short performance physical battery

    Baseline to week 4

  • Gait Speed as part of short performance physical battery

    Baseline to week 4

  • 6 Minute Walking Endurance Test

    Baseline to week 4

  • Balance test as part of short performance physical battery

    Baseline to week 4

  • Balance assessment via force plates

    Baseline to week 4

  • +5 more secondary outcomes

Study Arms (2)

PeptiStrong + whey protein

EXPERIMENTAL

2.4g PeptiStrong (provides 1.6g protein) + 8.4g of whey protein = 10g total protein

Dietary Supplement: PeptiStrong + whey protein

Whey protein

ACTIVE COMPARATOR

20g whey protein

Dietary Supplement: Whey protein

Interventions

PeptiStrong + whey proteinDIETARY_SUPPLEMENT

Fava bean protein hydrolysate containing bioactive peptides mixed with whey protein as dry powder for drinkable protein shake

PeptiStrong + whey protein
Whey proteinDIETARY_SUPPLEMENT

Whey protein as dry powder for drinkable protein shake

Whey protein

Eligibility Criteria

Age60 Years - 85 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Men and women aged 60 to 85 years at the time of enrolment
  • Community-dwelling (living independently or with minimal assistance)
  • Able to walk independently (with or without a walking aid) and complete simple physical function tests (such as standing up from a chair and walking short distances)
  • Willing and able to attend two study visits at the research facility (baseline and end of study)
  • Willing and able to consume a protein drink containing whey protein (derived from milk) once daily for 30 days
  • Able to understand the study information and provide written informed consent

You may not qualify if:

  • Any known food allergy or intolerance to fava bean protein or milk protein
  • Diagnosed kidney disease or any medical condition where increased protein intake is contraindicated
  • Yes to any of the answers on the "Older Adult Functional Assessment Screening Questionnaire"
  • Individuals with implanted electronic devices
  • Current or recent (within the past 3 months) participation in another clinical research study involving a nutritional or exercise intervention
  • Conditions that significantly impair mobility or balance such that safe completion of the physical function tests is not possible

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

LJMU, Byrom Street

Liverpool, L3 3AF, United Kingdom

RECRUITING

MeSH Terms

Interventions

Whey Proteins

Intervention Hierarchy (Ancestors)

Milk ProteinsAnimal Proteins, DietaryDietary ProteinsProteinsAmino Acids, Peptides, and ProteinsWheyMilkDairy ProductsFoodDiet, Food, and NutritionPhysiological PhenomenaFood and Beverages

Study Officials

  • Graeme Close, Professor

    Liverpool John Moore University

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Niamh Mohan, PhD

CONTACT

+353 1 430 1290mohan.niamh@nuritas.com

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
QUADRUPLE
Who Masked
PARTICIPANT, CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
OTHER
Intervention Model
PARALLEL
Model Details: Randomized, double-blind, placebo-controlled, parallel study conducted over 4 weeks
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 30, 2026

First Posted

April 14, 2026

Study Start

April 6, 2026

Primary Completion (Estimated)

July 30, 2026

Study Completion (Estimated)

October 30, 2026

Last Updated

May 6, 2026

Record last verified: 2026-04

Data Sharing

IPD Sharing
Will not share

Locations

GB(1)