Plant Based Protein and Whey Protein: Effects on Body Composition and Performance

NCT05228236 | Completed

• 1 other identifier: BetteryLifeLab4BP
• Study Type: interventional
• Target: 50
• Locations: 1 country
• Sites: 1

Brief Summary

This study aimed to investigate the effects of a newly developed plant-based protein blend regarding health and safety, body composition, and performance on healthy and physically active adult individuals, specifically team sports athletes. A randomized, double-blind, controlled trial was used to compare the effects of the plant-based protein versus whey protein, after an 8-week supplementation protocol, on body composition, biochemical markers, muscle strength and power, as well as aerobic performance in male futsal players. The working hypothesis is that this special blend of plant-based protein will be equivalent to whey protein, not only regarding body composition and performance, but also insofar as health and safety at the biochemical and physiological level.

Conditions

Protein Supplementation

Keywords

Plant-based Protein; Body composition; Physical Performance; Biochemical Health Markers; Supplementation

Outcome Measures

Primary Outcomes (17)

• Body composition parameter - change in fat free mass (FFM)

  FFM (kg) was assessed by dual energy X-ray absorptiometry

  Baseline, week 4 and week 8

• Body composition parameter - change in fat mass (FM)

  FM (%) was assessed by dual energy X-ray absorptiometry

  Baseline, week 4 and week 8

• Body composition parameter - change in muscle thickness

  muscle thickness of the rectus femoris (mm) was assessed by ultrasonography

  Baseline, week 4 and week 8

• Body composition parameter - change in body water

  total body water, intracellular water and extracellular water (L) were assessed by bioelectrical impedance analysis

  Baseline, week 4 and week 8

• Performance parameter - change in strength

  Maximal isometric forearm strength (N) was assessed using a handgrip dynamometer

  Baseline, week 4 and week 8

• Performance parameter - change in maximum strength

  Maximum strength (kg) was predicted from 1-RM in back squat and bench press exercises using a Multipower machine withVitruve technology

  Baseline, week 4 and week 8

• Performance parameter - change in peak power

  Muscle power (Watt) was assessed with a supramaximal cycling test on cycle ergometer

  Baseline, week 4 and week 8

• Performance parameter - change in jump height

  Vertical jump height (cm) was assessed on a multicomponent force platform interfaced with the Chronojump software

  Baseline, week 4 and week 8

• Aerobic performance - change in Oxygen uptake

  VO2peak (mL.kg-1.min-1) was assessed using breath-by-breath gas analyzer in an incremental test performed on a treadmill

  Baseline, week 4 and week 8

• Aerobic performance - change in Oxygen uptake

  Maximal aerobic speed (km/h) was assessed in an incremental test performed on a treadmill

  Baseline, week 4 and week 8

• biochemical health markers - change in cortisol

  Salivary cortisol was assessed using spectrophotometry techniques in an automated equipment.

  Baseline, week 4 and week 8

• biochemical health markers - change in creatinine

  plasma creatinine was assessed using spectrophotometry techniques in an automated equipment.

  Baseline, week 4 and week 8

• biochemical health markers - change creatine kinase

  plasma creatine kinase was assessed using spectrophotometry techniques in an automated equipment.

  Baseline, week 4 and week 8

• biochemical health markers - change in glucose

  plasma glucose was assessed using spectrophotometry techniques in an automated equipment.

  Baseline, week 4 and week 8

• biochemical health markers - change in C reactive protein

  plasma C Reactive Protein was assessed using spectrophotometry techniques in an automated equipment.

  Baseline, week 4 and week 8

• biochemical health markers - change in Aspartate Aminotransferase

  plasma Aspartate Aminotransferase was assessed using spectrophotometry techniques in an automated equipment.

  Baseline, week 4 and week 8

• biochemical health markers - change in alanine aminotransferase

  Plasma alanine aminotransferase was assessed using spectrophotometry techniques in an automated equipment.

  Baseline, week 4 and week 8

Secondary Outcomes (2)

• Body composition parameter - change in phase angle

  Baseline, week 4 and week 8

• Body composition parameter - change of visceral fat

  Baseline, week 4 and week 8

Study Arms (2)

Plant based protein

EXPERIMENTAL

Dietary Supplement: Plant based protein

Whey Protein

EXPERIMENTAL

Dietary Supplement: Whey protein

Interventions

Plant based protein DIETARY_SUPPLEMENT

A single dose of \~30 g of a plant-based protein blend was ingested 30-60 min after physical practice in training days or 30-60 min before bedtime in resting days.

Plant based protein

Whey protein DIETARY_SUPPLEMENT

A single dose of \~30 g of whey protein was ingested 30-60 min after physical practice in training days or 30-60 min before bedtime in resting days.

Whey Protein

Eligibility Criteria

• Age: 18 Years - 35 Years
• Sex: male
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Subjects currently engaged in a Futsal training program in a competition team, currently engaged in practice for at least 1 year and at least 3 times per week.

You may not qualify if:

• Individuals taking any type of drug (including anabolic steroids), medicines or supplements that may enhance body composition or performance, 3 months prior to the beginning of the trial.
• Clinical diagnose of a disease that might compromise tolerance to the supplements or influence body composition or performance.

Sponsors & Collaborators

• Bettery S.A.: lead

Study Sites (1)

Bettery S.A.

Oeiras, Porto Salvo, 2740-262, Portugal

Location

MeSH Terms

Interventions

Whey Proteins

Intervention Hierarchy (Ancestors)

Milk Proteins; Animal Proteins, Dietary; Dietary Proteins; Proteins; Amino Acids, Peptides, and Proteins; Whey; Milk; Dairy Products; Food; Diet, Food, and Nutrition; Physiological Phenomena; Food and Beverages

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, INVESTIGATOR
• Purpose: BASIC SCIENCE
• Intervention Model: PARALLEL
• Sponsor Type: INDUSTRY
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Innovation Manager

Study Record Dates

• First Submitted: January 13, 2022
• First Posted: February 8, 2022
• Study Start: September 1, 2021
• Primary Completion: December 10, 2021
• Study Completion: December 10, 2021
• Last Updated: February 8, 2022

Record last verified: 2022-01

Data Sharing

• IPD Sharing: Will not share

Locations

PT (1)