Digital Planning and Clinical Assessment of the Treated Atrophic Posterior Maxilla With a Sinus Lift Procedure: a Cross-sectional Study.

NCT07526337 | Recruiting

• 1 other identifier: CER-2025-137
• Study Type: observational
• Target: 100
• Locations: 1 country
• Sites: 1

Brief Summary

Maxillary posterior area is the most challenging site for dental implant placement. Indeed, complex remodeling processes, resulting in changes of the maxillary sinus and shape of the alveolar ridge will cause difficulties in rehabilitating the posterior maxillae sites. Various techniques have been proposed in order to achieve the necessary bone volume for the placement of long term successful implants. However, unbalanced crown to implant ratio remains a risk factor after successful dental implants installation following sinus graft. No study on humans assessed the effect of apical positioning of the implants in posterior grafted sites (sinus graft or sinus graft + vertical GBR) on the following clinical parameters: The peri-implant bone remodeling (vertical bone loss (mm) and probing depth (mm) around the implants, crown bulkiness, emergence profile and crown height, and Patients satisfaction, food impaction (PROM)). This study will elucidate these points and based on the parameter's results, suggest a treatment based classification facilitating the treatment decision-making of the clinicians in case of an atrophic posterior maxilla; aiming to ensure a long-term successful supra-implant rehabilitation which will maintain its bio-mechanically and biological success.

Conditions

Alveolar Bone Atrophy; Alveolar Bone Grafting; Peri-Implant Health; Sinus Floor Augmentation; Vertical Ridge Deficiency; Guided Bone Regeneration; Digital Guided Bone Regeneration; Prosthetic Complication

Keywords

alveolar bone atrophy; digital planning; guided bone regeneration; maxillary sinus; peri-implant disease; peri-implantits; sinus floor augmentation; vertical ridge deficiency

Outcome Measures

Primary Outcomes (3)

• peri-implant marginal bone remodeling (mm)

  Recorded at the mesial and distal aspect of each implant. The distance from the implant-abutment interface to the first bone-to-implant contact (bone level) was assessed on peri-apical radiographs taken with the long cone paralleling technique that were taken during the recall visits (after implant loading). Bone Level values were calibrated according to the actual implant length, following the next formula, according to Chen et al. 2023: (99) The BL was measured at the mesial (M) and distal (D) aspects of each implant at baseline (initial bone level, IBL) and follow-up (final bone level, FBL). The change in MBL was calculated as the difference between the mean FBL and mean IBL. The following formulas were used: (99).

  3 years

• - Pocket probing depth (mm).

  is measured with the periodontal probe Hu-Friedy Periodontal Probe PCP UNC15 (Hu-Friedy, Chicago, Illinois), going parallel to the axis of the implant to the nearest 0.5 mm, at 6 different sites per implant (mesiobuccal, buccal, distobuccal, mesiopalatal, palatal, distopalatal)

  1 week

• - Bleeding on probing.

  analyzed 15 seconds following pocket probing around 6 sites per implant.

  1 week

Secondary Outcomes (5)

• - Keratinized tissue width (mm).

  1 week

• - Crown-to-implant ratio

  1 week

• - Crown height and diameter

  1 week

• - Emergence angle (supra-implant crown bulkiness and height)

  1 week

• patient reported outcome measures (PROMs)

  1 week

Study Arms (1)

1

partially edentulous patients having an implant rehabilitation treated with a sinus lift procedure in the atrophic posterior maxilla

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

This study consists of recruiting a number of files of patients having placed posterior implants in an atrophic posterior maxilla treated with a sinus augmentation procedure.

You may qualify if:

• \- Patient aged more than 18 years.
• Partially edentulous patients having an implant rehabilitation treated with a sinus lift procedure in the atrophic posterior maxilla.
• Patient with no systemic disease that contraindicate the surgical procedure as uncontrolled diabetes mellitus, bleeding disorders, recent myocardial infarction, head and neck radiation, and mental disorders.

You may not qualify if:

• \- Fully Edentulous patients.
• Patients presenting sinus pathologies (sinusitis, thickening of the membrane).
• Patient smoking more than 20 cigarettes.
• Patient taking systemic drugs that could affect bone healing as immune suppressive drugs and bisphosphonates.
• Patient with systemic disease that contraindicate the surgical procedure as uncontrolled diabetes mellitus, bleeding disorders, recent myocardial infarction, head and neck radiation, and mental disorders.

Sponsors & Collaborators

• Saint-Joseph University: lead

Study Sites (1)

Saint Joseph University of Beirut

Beirut, Beyrouth, 1000, Lebanon

RECRUITING

MeSH Terms

Conditions

Alveolar Bone Loss

Condition Hierarchy (Ancestors)

Bone Resorption; Bone Diseases; Musculoskeletal Diseases; Periodontal Atrophy; Periodontal Diseases; Mouth Diseases; Stomatognathic Diseases

Central Study Contacts

Joseph Ryan Younes, Doctor of Dental Surgery

CONTACT

+96176366696; josephryan.younes@net.usj.edu.lb

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: April 6, 2026
• First Posted: April 13, 2026
• Study Start: January 1, 2025
• Primary Completion: May 1, 2026
• Study Completion (Estimated): May 30, 2026
• Last Updated: April 13, 2026

Record last verified: 2026-04

Locations

LE (1)