NCT07525050

Brief Summary

The purpose of this research study is to test how different aspects of food including food processing affect eating behaviors.

Trial Health

63
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
40

participants targeted

Target at P25-P50 for not_applicable

Timeline
19mo left

Started May 2026

Geographic Reach
1 country

1 active site

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress1%
May 2026Dec 2027

First Submitted

Initial submission to the registry

April 6, 2026

Completed
7 days until next milestone

First Posted

Study publicly available on registry

April 13, 2026

Completed
18 days until next milestone

Study Start

First participant enrolled

May 1, 2026

Completed
1.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2027

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2027

Last Updated

April 13, 2026

Status Verified

April 1, 2026

Enrollment Period

1.6 years

First QC Date

April 6, 2026

Last Update Submit

April 6, 2026

Conditions

Outcome Measures

Primary Outcomes (1)

  • Difference in satiety as determined by visual analogue scales (VAS)

    Participants will complete VAS on satiety measures during each study visit

    Day 1, Day 15

Study Arms (2)

UPF breakfast then MPF breakfast

EXPERIMENTAL

Participants will consume the UPF breakfast during the first study visit and the MPF breakfast during the second study visit

Other: UPF breakfast/MPF breakfast

MPF breakfast then UPF breakfast

EXPERIMENTAL

Participants will consume the MPF breakfast during the first study visit and the UPF breakfast during the second study visit

Other: MPF breakfast/UPF breakfast

Interventions

Participants will be provided with the UPF breakfast during the first study visit and the MPF breakfast during the second study visit

UPF breakfast then MPF breakfast

Participants will be provided with the MPF breakfast during the first study visit and the UPF breakfast during the second study visit

MPF breakfast then UPF breakfast

Eligibility Criteria

Age18 Years - 50 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • do not have restrictive eating practices
  • regularly consume breakfast
  • able to understand and sign the consent form
  • have own transportation to the research center
  • not allergic to study foods or unwilling to eat them
  • willing to comply with study demands
  • able to read and understand English
  • available to attend two in-person visits on a weekday and/or Saturday morning from 7:15 a.m. to 12:15 p.m.

You may not qualify if:

  • taking statins, medication to lower blood pressure, anti-inflammatory, anti-diabetes, or weight-loss medications
  • pregnant, lactating, or planning to become pregnant
  • diagnosed with an eating disorder, hypothyroidism, or cancer
  • allergy to study foods or express unwillingness to consume them
  • have gained or lost more than 10 pounds in the last 3 months
  • regular participants in vigorous endurance or resistance exercise (e.g., marathons, endurance bike races, triathlons, CrossFit, powerlifting)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

USDA ARS Grand Forks Human Nutrition Research Center

Grand Forks, North Dakota, 58203, United States

Location

Study Officials

  • Julie Hess, PhD

    USDA Grand Forks Human Nutrition Research Center

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Julie Hess, PhD

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, INVESTIGATOR
Purpose
OTHER
Intervention Model
CROSSOVER
Sponsor Type
FED
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Research Nutritionist

Study Record Dates

First Submitted

April 6, 2026

First Posted

April 13, 2026

Study Start

May 1, 2026

Primary Completion (Estimated)

December 1, 2027

Study Completion (Estimated)

December 1, 2027

Last Updated

April 13, 2026

Record last verified: 2026-04

Data Sharing

IPD Sharing
Will not share

Locations