NCT07524686

Brief Summary

Low back pain with lumbar radiculopathy is a common condition that significantly affects functional ability and quality of life. Manual therapy is widely used as a first-line treatment to reduce pain and improve mobility. This study aims to compare the effectiveness of spinal mobilization with leg movement (SMWLM) and neurodynamic mobilization in patients with lumbar radiculopathy. A total of 20 participants were randomly assigned into two groups. One group received SMWLM, while the other group received neurodynamic mobilization of the sciatic nerve over a treatment period of six weeks. Outcomes included pain intensity, quality of life, and hip range of motion. The results of this study aim to identify the more effective intervention for improving clinical outcomes in patients with lumbar radiculopathy.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
20

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Oct 2025

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 10, 2025

Completed
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 31, 2026

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

January 31, 2026

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

April 6, 2026

Completed
7 days until next milestone

First Posted

Study publicly available on registry

April 13, 2026

Completed
Last Updated

April 13, 2026

Status Verified

April 1, 2026

Enrollment Period

4 months

First QC Date

April 6, 2026

Last Update Submit

April 6, 2026

Conditions

Lumbar RadiculopathyLow Back Pain

Keywords

Spinal MobilizationNeurodynamic MobilizationLumbar Radiculopathy

Outcome Measures

Primary Outcomes (3)

  • Pain Intensity (Visual Analogue Scale)

    Pain intensity was measured using the Visual Analogue Scale (VAS), where 0 indicates no pain, and 10 indicates the worst possible pain.

    Baseline and after 6 weeks of treatment

  • Functional Disability (Oswestry Disability Index)

    Functional disability was assessed using the Oswestry Disability Index (ODI), which evaluates limitations in daily activities due to low back pain.

    Baseline and after 6 weeks of treatment

  • Hip Range of Motion

    Hip range of motion was measured using a universal goniometer to assess improvements in joint mobility.

    Baseline and after 6 weeks of treatment

Study Arms (2)

Spinal Mobilization With Leg Movement Group

EXPERIMENTAL

Participants in this group received spinal mobilization with leg movement (SMWLM) based on the Mulligan concept to improve spinal mobility, reduce pain, and enhance functional performance.

Other: Spinal Mobilization With Leg Movement

Neurodynamic Mobilization Group

EXPERIMENTAL

Participants in this group received neurodynamic mobilization targeting the sciatic nerve to improve neural mobility and reduce pain associated with lumbar radiculopathy.

Other: Neurodynamic Mobilization

Interventions

Spinal Mobilization With Leg MovementOTHER

This intervention involves applying sustained accessory spinal mobilization combined with active or passive leg movement to improve joint mechanics, reduce nerve compression, and enhance mobility.

Spinal Mobilization With Leg Movement Group
Neurodynamic MobilizationOTHER

Neurodynamic mobilization techniques were applied to mobilize the sciatic nerve and surrounding tissues to restore neural function, reduce tension, and improve mobility.

Neurodynamic Mobilization Group

Eligibility Criteria

Age25 Years - 50 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Age between 25 and 50 years
  • Male and female participants
  • Clinically diagnosed low back pain with lumbar radiculopathy for at least 3 months
  • Symptoms radiating below the knee along the sciatic nerve distribution

You may not qualify if:

  • History of lumbar spine surgery or laminectomy
  • Spinal fractures, tumors, or inflammatory disorders
  • Acute disc prolapse or lumbar instability
  • Lower limb vascular disease
  • Neurological disorders
  • Piriformis syndrome
  • Manual therapy within the last 6 months
  • Hip pathology or hamstring tightness

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Deraya university, faculty of physical therapy

Minya, Menia Governorate, Egypt

Location

MeSH Terms

Conditions

RadiculopathyLow Back Pain

Condition Hierarchy (Ancestors)

Peripheral Nervous System DiseasesNeuromuscular DiseasesNervous System DiseasesBack PainPainNeurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, INVESTIGATOR
Masking Details
This study was single-blinded where participants and investigators were not fully aware of group allocation details to minimize bias.
Purpose
TREATMENT
Intervention Model
PARALLEL
Model Details: Participants were randomly assigned into two parallel groups. One group received spinal mobilization with leg movement, while the other group received neurodynamic mobilization. Outcomes were compared after completion of the intervention period.
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

April 6, 2026

First Posted

April 13, 2026

Study Start

October 10, 2025

Primary Completion

January 31, 2026

Study Completion

January 31, 2026

Last Updated

April 13, 2026

Record last verified: 2026-04

Data Sharing

IPD Sharing
Will not share

Locations

EG(1)