Effect of Sciatic Nerve Neurodynamic Sliding on Pain, Disability, and Balance in Patients With Lumbar Radiculopathy

NCT07458399 | Not Yet Recruiting

• 1 other identifier: P.T.REC/012/006269
• Study Type: interventional
• Target: 28
• Locations: 1 country
• Sites: 1

Brief Summary

This study will be conducted to evaluate the effect of sciatic nerve slider mobilization on pain intensity. Also, to evaluate the impact of sciatic nerve mobilization on functional disability, and to determine the influence of sciatic nerve slider neurodynamics on functional balance performance.

Conditions

Lumbar Radiculopathy

Outcome Measures

Primary Outcomes (3)

• Pain pressure threshold

  It will be assessed by pressure pain algometer to measure this tenderness to palpation. An electronic digital algometer (Biotronik Care, Mars OneSKU: SF1005, India). Manual palpation with mild pressure will be utilized from supine to the common peroneal nerve, which passes behind the head of the fibula and runs around the neck of the fibula; from prone to the sciatic nerve at the midpoint of a line from the ischial tuberosity to the greater trochanter of the femur; and the tibial nerve, which bisects the popliteal fossa at the midpoint of the popliteal crease. Positive reporting consists of pain or discomfort on the symptomatic side, as well as greater pain or discomfort on the symptomatic side than on the asymptomatic side. Three measurements will be performed at each test site, with a 10-second pause between each. The average of the three measurements will be calculated.

  6 weeks

• Functional Disability

  The Roland-Morris Disability Questionnaire will be used to assess functional disability. It includes 24 items with face validity to describe patients with low back pain. The Roland-Morris Disability Questionnaire has excellent psychometrics, is simple to administer, and has been found to be effective in therapy research studies. Items are scored 0 if left blank or 1 if endorsed, for a total RMQ score ranging from 0 to 24; higher scores represent higher levels of pain-related disability.

  6 weeks

• Balance Evaluation

  It will be assessed by the Berg Balance Scale (BBS) is an objective measure of static and dynamic balance abilities. The scale consists of 14 functional tasks commonly performed in everyday life. Scoring uses a five-point ordinal scale, with scores ranging from 0 to 4. Maximum score of 56 points is possible. Lower scores indicate poor balance.

  6 weeks

Study Arms (2)

Selected conventional physical therapy program group

ACTIVE COMPARATOR

The participants will receive selected conventional physical therapy program, 3 sessions per week for six weeks.

Other: Selected conventional physical therapy program

Sciatic nerve slider mobilization group

EXPERIMENTAL

The participants will receive sciatic nerve slider mobilization in addition to selected conventional physical therapy program, 3 sessions per week for six weeks.

Other: Selected conventional physical therapy program; Other: Sciatic nerve slider mobilization

Interventions

Selected conventional physical therapy program OTHER

The program will include: 1- Transcutaneous electrical nerve stimulation (TENS) will be applied at Lumbosacral area, with pulse frequency of 100 Hz for 15 minutes. 2\) Manual therapy intervention: Myofascial release will be performed on low back muscles and gluteus, piriformis, hamstring, and calf of the affected lower extremity applied for 20 minutes. Following side posture positional distraction, the wedge pillow will be removed and the patient is maintained in the same position. The physical therapist performed passive spinal rotation mobilization. Finally, high-velocity low-amplitude (HVLA) manipulation will be applied from the same position. 3\) Core stability exercises: They are consisted of of side plank on knee or ankle on both sides, and clamshell exercise. The clamshell exercise consists of three sets of ten repetitions. Side plank will be performed three times in a static manner for 10-20 seconds or up to patient failure.

Sciatic nerve slider mobilization group; Selected conventional physical therapy program group

Sciatic nerve slider mobilization OTHER

Mobilization will be applied from supine position, alternating hip flexion with knee extension and dorsiflexion, and knee flexion with plantar flexion, performed three times for 1 minute straight leg raising technique rhythmically

Sciatic nerve slider mobilization group

Eligibility Criteria

• Age: 25 Years - 45 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Chronic unilateral lumbar painful radiculopathy (duration ranged from 3 to 18 months).
• During the evaluation session, repeated lumbar movements did not improve or worsen lower extremity symptoms.
• Positive straight leg raise (SLR) response. A positive SLR test was defined as the presence of both of these findings: (1) the test reproduced the patient's symptoms and (2) the symptoms decreased with the ankle plantar flexion component of the test.
• Unilateral Pain radiating below the knee, with leg pain equal to or more severe than the accompanying back pain.
• The presence of paresthesia such as pins and needles or numbness in the affected limb, along with neurological deficits-whether motor, sensory, or reflex-that corresponded to the dermatome or myotome of the affected nerve root.

You may not qualify if:

• Systemic diseases such as autoimmune and metabolic diseases.
• Previous Lumbar Spine surgery.
• Lumbar spine stenosis.
• Spinal deformity.
• Spinal fracture.
• Bilateral lower extremity symptoms.
• Steroid injection or use of anti-inflammatory medications within two to four weeks prior to study commencement.

Sponsors & Collaborators

• Cairo University: lead

Study Sites (1)

Abdelrahman Taha El-sayed

Suez, Egypt

Location

MeSH Terms

Conditions

Radiculopathy

Condition Hierarchy (Ancestors)

Peripheral Nervous System Diseases; Neuromuscular Diseases; Nervous System Diseases

Study Officials

• Ebtesam Fahmy, Professor

  Cairo University

  STUDY DIRECTOR

• Rasha El-Rewainy, Professor

  Cairo University

  STUDY CHAIR

Central Study Contacts

Abdelrahman El-Sayed, Master

CONTACT

01091843750; Tahaabdelrahman07@gmail.com

Hoda Zayed, PHD

CONTACT

01111052808; hoda.zayed@cu.edu.eg

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal investigator

Study Record Dates

• First Submitted: March 4, 2026
• First Posted: March 9, 2026
• Study Start: March 10, 2026
• Primary Completion (Estimated): September 15, 2026
• Study Completion (Estimated): September 30, 2026
• Last Updated: March 9, 2026

Record last verified: 2026-03

Locations

EG (1)