NCT07523659

Brief Summary

Physical activity (PA) refers to bodily movements that result in a significant increase in energy expenditure due to the contraction of skeletal muscles. Physical inactivity has become a major global public health concern and is currently the fourth leading cause of death worldwide. The World Health Organization (WHO) recommends that adults engage in at least 150 minutes of moderate-intensity physical activity (MPA) or 75 minutes of vigorous-intensity physical activity (VPA) per week. Although some studies suggest that individual differences in PA may have a genetic basis, PA is generally considered to be largely under voluntary control and influenced by climatic and environmental factors. For instance, extreme temperatures-either hot or cold-can increase health risks and reduce individuals' willingness to engage in physical activity. In addition, air pollution, particularly fine particulate matter (PM2.5), poses serious health risks. Exercising in polluted environments may trigger asthma, cardiovascular, or pulmonary conditions. Since the Industrial Revolution, fossil fuel emissions have contributed to a global surface temperature increase of approximately 1.1°C, with projections suggesting a further rise of 2.5-2.9°C by the end of the century. At the same time, PM2.5 pollution has become a pressing issue, contributing to an estimated 7 million deaths globally in 2012-over one-third of which occurred in rapidly developing Asian countries. Given the seasonal and geographic variability in climate and air quality, physical activity levels are likely to be affected accordingly.This study aims to investigate the extent to which climatic and environmental factors influence physical activity levels and intensity.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
124

participants targeted

Target at P50-P75 for all trials

Timeline
2mo left

Started Aug 2024

Typical duration for all trials

Geographic Reach
1 country

2 active sites

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress90%
Aug 2024Aug 2026

Study Start

First participant enrolled

August 1, 2024

Completed
1 year until next milestone

First Submitted

Initial submission to the registry

August 11, 2025

Completed
8 months until next milestone

First Posted

Study publicly available on registry

April 13, 2026

Completed
5 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 31, 2026

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 31, 2026

Last Updated

April 13, 2026

Status Verified

March 1, 2026

Enrollment Period

2.1 years

First QC Date

August 11, 2025

Last Update Submit

April 8, 2026

Conditions

Outcome Measures

Primary Outcomes (1)

  • Physical activity level

    Physical activity in vector magnitude counts will be recorded using GT3X accelerometer worn near the hip for a consecutive period of 7 days. The monitor should not be worn while bathing or swimming.

    Through study completion, every two months across 6 assessment rounds, up to 12 months per participant

Secondary Outcomes (11)

  • Temperature

    Through study completion, an average of 2 years

  • Humidity

    Through study completion, an average of 2 years

  • Subject exposure to environmental temperature

    Through study completion, every two months across 6 assessment rounds, up to 12 months per participant

  • PM2.5

    Through study completion, an average of 2 years

  • Sunshine duration

    Through study completion, an average of 2 years

  • +6 more secondary outcomes

Study Arms (2)

Subjects in Shenzhen

The investigators planned to recruit 62 subjects in Shenzhen. Shenzhen is located in 22.324386ºN, 114.031040ºE, the south of China, with long summers and short winters, high temperatures and frequent rains. The average annual temperature is 23.3℃. In addition, Shenzhen is a city with good economic and technological development. The investigators will measure the physical activity of subjects, and the Temperature, humidity and PM2.5 data of Shenzhen.

Subjects in Shenyang

The investigators planned to recruit 62 subjects in Shenyang. Shenyang is located in 41.481175ºN, 123.253118ºE, the northeastern of China, with cold winters and warm summers, also has long cold periods. The average annual temperature ranges from 6.2 to 9.7℃. In addition, Shenyang focuses on industrial development. The investigators will measure the physical activity of subjects, and the Temperature, humidity and PM2.5 data of Shenyang.

Eligibility Criteria

Age18 Years - 55 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)
Sampling MethodProbability Sample
Study Population

The study population consisted of healthy individuals. Female participants were neither pregnant nor planning to become pregnant, and none were lactating. All subjects were free from serious illnesses or disabilities that could interfere with the study.

You may qualify if:

  • Aged 18 to 55 years
  • Residing in Shenzhen or Shenyang for the entire year

You may not qualify if:

  • Disabilities that limit physical activity
  • Any condition preventing participation in physical activity
  • Pregnant or planning pregnancy during the study period
  • Lactating or planning to lactate during the study period

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Shenzhen Institutes of Advanced Technology, Chinese Academy of Science

Shenzhen, Guangdong, China

RECRUITING

China Medical University

Shenyang, China

RECRUITING

MeSH Terms

Conditions

Motor Activity

Condition Hierarchy (Ancestors)

Behavior

Central Study Contacts

John R Speakman, Doctor

CONTACT

Xueying Zhang, Doctor

CONTACT

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
CROSS SECTIONAL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professer

Study Record Dates

First Submitted

August 11, 2025

First Posted

April 13, 2026

Study Start

August 1, 2024

Primary Completion (Estimated)

August 31, 2026

Study Completion (Estimated)

August 31, 2026

Last Updated

April 13, 2026

Record last verified: 2026-03

Locations