NCT07522138

Brief Summary

This study aims to test whether patients with Parkinson's disease can safely and effectively use a home-based exercise program guided by videos. Participants will follow video instructions for exercises at home while their movements are monitored by a camera, which provides real-time feedback. The study will check how well participants complete the exercises, their satisfaction with the program, and any changes in clinical function. The goal is to see if this type of home exercise can help patients increase their activity levels without significant side effects.

Trial Health

63
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
15

participants targeted

Target at below P25 for not_applicable

Timeline
8mo left

Started Apr 2026

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress18%
Apr 2026Feb 2027

First Submitted

Initial submission to the registry

April 3, 2026

Completed
10 days until next milestone

First Posted

Study publicly available on registry

April 13, 2026

Completed
7 days until next milestone

Study Start

First participant enrolled

April 20, 2026

Completed
8 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2026

Expected
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

February 28, 2027

Last Updated

April 15, 2026

Status Verified

April 1, 2026

Enrollment Period

8 months

First QC Date

April 3, 2026

Last Update Submit

April 12, 2026

Conditions

Outcome Measures

Primary Outcomes (1)

  • Movement Disorder Society-Unified Parkinson's Disease Rating Scale (MDS-UPDRS), Part III (Motor Examination)

    0 to 108, with higher scores indicating worse motor function.

    From enrollment to the end of treatment at 6 weeks

Secondary Outcomes (5)

  • Modified Hoehn and Yahr sacle

    From enrollment to the end of treatment at 6 weeks

  • Berg Balance Scale

    From enrollment to the end of treatment at 6 weeks

  • Functional Gait Ability

    From enrollment to the end of treatment at 6 weeks

  • Freezing of Gait Questionnaire

    From enrollment to the end of treatment at 6 weeks

  • EuroQol-5 Dimention Questionnaire

    From enrollment to the end of treatment at 6 weeks

Study Arms (1)

Home-based Exercise Program (Single Arm)

EXPERIMENTAL

Participants follow a 6-week home-based exercise program guided by instructional videos, including stretching, strength, balance, aerobic, and LSVT-specific exercises. A camera provides real-time feedback using the iPixel exercise feedback system, and participants complete sessions at least 5 times per week, 40 minutes per session, with weekly 30-minute in-person check-ins for monitoring and support.

Behavioral: Home-based self-exercise feedback program using video

Interventions

Participants follow a 6-week home-based exercise program using video-guided instructions and the iPixel exercise feedback system, which monitors movements in real-time and provides corrective feedback. The program includes: Stretching exercises, Strength training, Balance exercises, Aerobic exercises, LSVT-specific exercises. Participants are instructed to complete sessions at least 5 times per week, 40 minutes per session. Additionally, weekly 30-minute in-person rehabilitation sessions are conducted to adjust the next week's exercise intensity based on each participant's functional level.

Home-based Exercise Program (Single Arm)

Eligibility Criteria

Age19 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Adults aged 19 years or older, clinically diagnosed with Idiopathic Parkinson's Disease (PD) according to the Movement Disorder Society (MDS) clinical diagnostic criteria
  • Patients at Hoehn and Yahr stage 1-2.5
  • Patients on stable dopaminergic therapy with no changes in the past 1 month
  • Patients receiving Lee Silverman Voice Treatment (LSVT) rehabilitation therapy once weekly as outpatients
  • Patients who have voluntarily provided informed consent to participate in the study

You may not qualify if:

  • Patients diagnosed with atypical parkinsonism
  • Patients with musculoskeletal problems that make participation in rehabilitation difficult
  • Patients who have limited access to the video-based home exercise feedback program

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Seoul National University Bundang Hospital

Seongnam-si, 13620, South Korea

Location

Related Publications (4)

  • Colon-Semenza C, Latham NK, Quintiliani LM, Ellis TD. Peer Coaching Through mHealth Targeting Physical Activity in People With Parkinson Disease: Feasibility Study. JMIR Mhealth Uhealth. 2018 Feb 15;6(2):e42. doi: 10.2196/mhealth.8074.

  • van Nimwegen M, Speelman AD, Hofman-van Rossum EJ, Overeem S, Deeg DJ, Borm GF, van der Horst MH, Bloem BR, Munneke M. Physical inactivity in Parkinson's disease. J Neurol. 2011 Dec;258(12):2214-21. doi: 10.1007/s00415-011-6097-7. Epub 2011 May 26.

  • Politis M, Wu K, Molloy S, G Bain P, Chaudhuri KR, Piccini P. Parkinson's disease symptoms: the patient's perspective. Mov Disord. 2010 Aug 15;25(11):1646-51. doi: 10.1002/mds.23135.

  • Fox SH, Luca DG, Postuma RB, Bhidayasiri R, Cardoso F, Kovacs GG, Katzenschlager R, Trenkwalder C. Revisiting the 2015 MDS diagnostic criteria for Parkinson disease: insights from autopsy-confirmed cases. NPJ Parkinsons Dis. 2025 Dec 13;11(1):360. doi: 10.1038/s41531-025-01206-6.

MeSH Terms

Conditions

Parkinson Disease

Condition Hierarchy (Ancestors)

Parkinsonian DisordersBasal Ganglia DiseasesBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesMovement DisordersSynucleinopathiesNeurodegenerative Diseases

Study Officials

  • Won-Seok Kim, MD, PhD

    Seoul National University Bundang Hospital

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Won-Seok Kim, MD, PhD

CONTACT

SunJeong Gwon, BS

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Model Details: This is a single-arm, prospective interventional study in which all participants receive the same 6-week home-based video-guided exercise program. There is no control or comparator group, and the primary goal is to assess feasibility, adherence, safety, and functional outcomes in patients with Idiopathic Parkinson's Disease. Participants are monitored throughout the study period, with weekly 30-minute in-person rehabilitation sessions to adjust exercise intensity based on functional level. Assessments are conducted both before and immediately after the intervention, including exercise adherence, patient satisfaction, and clinical function evaluations.
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

April 3, 2026

First Posted

April 13, 2026

Study Start

April 20, 2026

Primary Completion (Estimated)

December 1, 2026

Study Completion (Estimated)

February 28, 2027

Last Updated

April 15, 2026

Record last verified: 2026-04

Locations