Vaginal Vault Native Tissue Suspension
Efficacy of a Novel Mackenrodt Uterosacral Double Ligaments Vault Suspension for Treatment of Pelvic Organ Prolapse
1 other identifier
interventional
10
1 country
1
Brief Summary
Vaginal vault suspension at time of abdominal hysterectomy using Mackenrodt and uterosacral ligaments.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for not_applicable
Started Jun 2026
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
April 2, 2026
CompletedFirst Posted
Study publicly available on registry
April 8, 2026
CompletedStudy Start
First participant enrolled
June 3, 2026
CompletedPrimary Completion
Last participant's last visit for primary outcome
April 1, 2027
ExpectedStudy Completion
Last participant's last visit for all outcomes
June 1, 2027
June 4, 2026
April 1, 2026
10 months
April 2, 2026
June 3, 2026
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Pelvic organ prolapse Stage
Increase stage means bad outcome Minimum: 0 , Maximum:4
3 months
Study Arms (1)
Suspension group
EXPERIMENTALInterventions
Total hysterectomy will be performed and vaginal vault will be closed with absorbable vicryl sutures The pelvis is then inspected and both uterosacral ligaments and ureters are identified. The proximal part of the mid-portion of each ligament is grasped and put under tension. In case of proximity to the ureter, a peritoneal release incision is performed to avoid kinking of the ipsilateral ureter. A Vicryl 1/0 suture is then used and passed through the proximal portion of the ligament approximately 1 cm distal to its sacral origin, in order to avoid entrapment of S3 nerve root. The suture is then passed through the mid portion of the ligament in one or two bites and secured to the posterior vaginal wall.hese steps are repeated in the contralateral ligament. Manchester procedure: Vicryl 1 suture will pass through Mackenrodt ligament and then fixed to the anterior vaginal wall. The suture is repeated on the opposite side ,so both Mackenrodt ligaments will be fixed th anterior vagina
Eligibility Criteria
You may qualify if:
- women undergoing hysterectomy
- Stage 1 or more pelvic organ prolapse
You may not qualify if:
- pregnacy or 6 months postpartum
- previous suspension surgery
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Women's Health Hospital
Asyut, Egypt
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Women H Hospital
Women's health hospital
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- NA
- Masking
- NONE
- Purpose
- TREATMENT
- Intervention Model
- SINGLE GROUP
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Lecturer obstetric and gynecology, Specialist Urogynecology
Study Record Dates
First Submitted
April 2, 2026
First Posted
April 8, 2026
Study Start
June 3, 2026
Primary Completion (Estimated)
April 1, 2027
Study Completion (Estimated)
June 1, 2027
Last Updated
June 4, 2026
Record last verified: 2026-04