Bilateral Erector Spinae Plane Block Versus Bilateral Quadratus Lumborum Plane Block for Postoperative Anaelgesia After Lumbar Spine Surgery

NCT07517822 | Active Not Recruiting Phase 4 DMC

• 1 other identifier: MMASU 15/2024
• Study Type: interventional
• Target: 40
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of this study is to compare postoperative analgesia and duration for each block performance plus complications after surgery in lumbar spine fixation.

Conditions

Anaesthesia

Outcome Measures

Primary Outcomes (1)

• Comparison between postoperative analgesia of QLB and ESPB after lumbar spine surgery via VAS score measurement

  The Visual Analog Scale (VAS) is used to assess pain intensity. It consists of a 10 cm line where 0 indicates "no pain" and 10 indicates "the worst possible pain." Higher scores indicate greater pain intensity.

  VAS Score will be used to assess pain or discomfort in postoperative at 2, 4, 6, 12, 24 hours

Study Arms (2)

Ultrasound-guided quadratus lumborum block

ACTIVE COMPARATOR

Procedure: Ultrasound-guided quadratus lumborum block (QLB)

Ultrasound Guided Erector Spinae Plane Block (ESPB)

ACTIVE COMPARATOR

Procedure: Ultrasound-guided quadratus lumborum block (QLB)

Interventions

Ultrasound-guided quadratus lumborum block (QLB) PROCEDURE

And ultrasound guided QLB block with transmuscular approach was performed using 0.5 ml/kg 0.25% bupivacaine to the patients in QLB group

Ultrasound Guided Erector Spinae Plane Block (ESPB); Ultrasound-guided quadratus lumborum block

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Aged between 18 and 65 years.
• American Society of Anesthesiologists (ASA) physical status I to II.
• Body mass index (BMI) less than 35 kg/m2.

You may not qualify if:

• Revision surgery.
• More than three levels surgery.
• Abnormal state of blood coagulation.
• Chronic opioid consumption.
• Local infection at the injection site).
• Allergy to any involved medications.
• Taking opioids within the past two weeks prior to surgery.
• Time of surgery more than 4 hours.

Sponsors & Collaborators

• Ain Shams University: lead

Study Sites (1)

AinShamsU

Cairo, Cairo Governorate, 11511, Egypt

Location

Related Publications (1)

• Fakhry, Mahmoud, D., ElMoutaz Mahmoud, H., Yehia Kassim, D. & NegmEldeen AbdElAzeem, H. 2024. Erector spinae plane block versus quadratus lumborum block for postoperative analgesia after laparoscopic resection of colorectal cancer: A prospective randomized study. Anesthesiol Res Pract, 20, 10.

  BACKGROUND

Study Design

• Study Type: interventional
• Phase: phase 4
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: INVESTIGATOR
• Purpose: PREVENTION
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: April 2, 2026
• First Posted: April 8, 2026
• Study Start: December 1, 2025
• Primary Completion: June 1, 2026
• Study Completion: July 1, 2026
• Last Updated: April 8, 2026

Record last verified: 2026-04

Data Sharing

• IPD Sharing: Will not share

Locations

EG (1)