Communication Intervention to Improve Influenza Vaccination Rates Among Elderly in Can Tho

NCT07508189 | Active Not Recruiting

• 1 other identifier: NIHE IRB - 40/2025
• Study Type: interventional
• Target: 1,200
• Locations: 1 country
• Sites: 1

Brief Summary

This study evaluates the effectiveness of a community-based communication intervention to increase influenza vaccination rates among the elderly (aged above 65) in Can Tho City, Vietnam. Using a cluster randomized controlled trial design, the intervention includes direct counseling, social media engagement (Zalo), and educational materials targeting the elderly, their relatives, and local health workers. The primary goal is to assess changes in vaccination coverage over a 9-month period.

Conditions

Influenza; Vaccination Coverage; Health Communication

Keywords

Influenza Vaccines; Elderly; Health Communication; Vaccination Coverage; Community-based Intervention; Vietnam

Outcome Measures

Primary Outcomes (1)

• Change in Influenza Vaccination Coverage Rate

  The primary outcome is the change in the proportion of elderly participants who received the influenza vaccine from baseline to 12 months. Effectiveness will be evaluated by comparing the intervention and control groups using the Difference-in-Differences (DID) analytical method.

  Baseline (Month 0) and Post-intervention (Month 12)

Study Arms (2)

Multi-component Health Communication

EXPERIMENTAL

Elderly participants in this arm will receive a multi-component health communication package, including direct counseling from health workers, social media engagement via Zalo, and printed materials (leaflets).

Behavioral: Multi-component Health Communication Package

Routine Immunization Information

NO INTERVENTION

Participants in this arm receive standard care and routine immunization information provided by the local health station without the additional communication package.

Interventions

Multi-component Health Communication Package BEHAVIORAL

A 12-month intervention program consisting of: 1) Direct health counseling; 2) Weekly educational content shared via Zalo; and 3) Distribution of influenza vaccination leaflets.

Multi-component Health Communication

Eligibility Criteria

• Age: 66 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Older Adult (65+)

You may qualify if:

• Residents living in selected wards/communes in Can Tho City for at least 6 months.
• Aged above 65 years.
• Mentally and physically capable of participating in interviews and receiving communication interventions.
• Agree to participate in the study and provide informed consent.

You may not qualify if:

• Individuals with severe cognitive impairment or dementia.
• Individuals with contraindications to influenza vaccination.
• Planning to move out of the study area during the 12-month follow-up period.

Sponsors & Collaborators

• Can Tho University of Medicine and Pharmacy: lead
• National Institute of Hygiene and Epidemiology, Vietnam: collaborator

Study Sites (1)

Can Tho University of Medicine and Pharmacy

Can Tho, Can Tho City, 900000, Vietnam

Location

MeSH Terms

Conditions

Influenza, Human

Condition Hierarchy (Ancestors)

Respiratory Tract Infections; Infections; Orthomyxoviridae Infections; RNA Virus Infections; Virus Diseases; Respiratory Tract Diseases

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Masking Details: Due to the nature of the community-based health communication intervention, masking of participants and investigators is not feasible.
• Purpose: PREVENTION
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Model Details: A cluster randomized controlled trial where wards/communes are the unit of randomization. Participants in intervention clusters receive multi-component communication, while control clusters receive standard care.

Study Record Dates

• First Submitted: March 27, 2026
• First Posted: April 2, 2026
• Study Start: September 1, 2015
• Primary Completion (Estimated): September 1, 2026
• Study Completion (Estimated): December 31, 2026
• Last Updated: April 8, 2026

Record last verified: 2026-04

Data Sharing

• IPD Sharing: Will not share

Locations

VN (1)