NCT07508150

Brief Summary

Accurate normalization of peak torque (PT) is critical for comparing muscle strength across individuals of varying body composition. While body weight (BW) is commonly used, body mass index (BMI) may provide a more stable representation of inter-individual variability. The study aims to compare the effects of BW and BMI normalization on inter-individual variability of trunk, hip, and knee muscle strength in healthy female participants.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
112

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Mar 2026

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

March 27, 2026

Completed
3 days until next milestone

Study Start

First participant enrolled

March 30, 2026

Completed
3 days until next milestone

First Posted

Study publicly available on registry

April 2, 2026

Completed
26 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 28, 2026

Completed
2 days until next milestone

Study Completion

Last participant's last visit for all outcomes

April 30, 2026

Completed
Last Updated

April 9, 2026

Status Verified

April 1, 2026

Enrollment Period

29 days

First QC Date

March 27, 2026

Last Update Submit

April 7, 2026

Conditions

Healthy

Keywords

Isokinetic strengthPeak torqueNormalizationBody weightBody mass index

Outcome Measures

Primary Outcomes (2)

  • trunk muscle peak torque

    Isokinetic trunk muscle strength testing

    two weeks

  • hip muscle peak torque

    Isokinetic hip muscle strength testing

    two weeks

Interventions

effects of BW versus BMI normalization on inter-individual variability of trunk, hip, and knee muscle strength in healthy femaleDIAGNOSTIC_TEST

effects of BW and BMI normalization on inter-individual variability of trunk, hip, and knee muscle strength in healthy female

Eligibility Criteria

Age25 Years - 35 Years
Sexfemale(Gender-based eligibility)
Healthy VolunteersYes
Age GroupsAdult (18-64)
Sampling MethodNon-Probability Sample
Study Population

A total of 112 healthy sedentary females volunteered to participate in the study. Their demographic characteristics including age, weight, height and BMI are illustrated in Table 1. Ethical approval was obtained from the Research Ethics Committee of the Faculty of Physical Therapy, Cairo University. Prior to enrollment, all participants provided written informed consent after receiving a comprehensive explanation of the study objectives, procedures, and their rights as research subjects. All procedures were performed in accordance with the Helsinki Declaration. All participants provided informed written consent prior to participation, aligning with ethical standards for research with human subjects.

You may qualify if:

  • he absence of any current or prior musculoskeletal injury or pain affecting the trunk, pelvis, or lower extremities within the preceding six months.
  • absence of neurological, cardiovascular, or systemic conditions that could influence muscle strength or motor performance.
  • a normal BMI relative to their age and sex and were recreationally active without engaging in any structured strength training program targeting the trunk or hip muscles during the three months preceding the study.
  • all participants were able to comprehend the study procedures and provide written informed consent.

You may not qualify if:

  • any history of musculoskeletal injury, surgery, or chronic pain involving the spine, pelvis, hip, knee, or ankle. Individuals with diagnosed neurological disorders, balance impairments, or vestibular conditions were also ineligible.
  • cardiovascular, respiratory, or systemic diseases that could affect physical performance or muscle strength were excluded
  • a prior history of lower limb or trunk fractures. Individuals engaged in competitive sports or structured resistance training programs targeting the trunk and lower limb muscles within the preceding three months were not included.
  • musculoskeletal deformities, leg length discrepancies, or any other condition that could interfere with the testing procedures

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Faculty of Physical Therapy, Cairo University

Giza, 12511, Egypt

Location

Related Links

MeSH Terms

Conditions

Body Weight

Condition Hierarchy (Ancestors)

Signs and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • Azza M, professor

    Cairo University

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Azza M Abdelmohsen, professor

CONTACT

01145046304dr_azzamohammed@yahoo.com

Azza M, professor

CONTACT

01145046304dr_azzamohammed@yahoo.com

Study Design

Study Type
observational
Observational Model
OTHER
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
professor

Study Record Dates

First Submitted

March 27, 2026

First Posted

April 2, 2026

Study Start

March 30, 2026

Primary Completion

April 28, 2026

Study Completion

April 30, 2026

Last Updated

April 9, 2026

Record last verified: 2026-04

Data Sharing

IPD Sharing
Will not share

Locations

EG(1)