Tele-assessment and Face-to-face Assessment of the 30-second Sit-stand Test in Peripheral Artery Disease

NCT07497360 | Recruiting

• 1 other identifier: 2025/43-08
• Study Type: observational
• Target: 45
• Locations: 1 country
• Sites: 1

Brief Summary

Peripheral artery disease (PAD) is a chronic and progressive condition caused by narrowing or blockage of arteries in the lower limbs due to atherosclerosis. It primarily affects adults over 50, with prevalence increasing with age, and its clinical presentation ranges from asymptomatic cases to severe ischemia that may require amputation. Intermittent claudication, characterized by exercise-induced leg pain that resolves with rest, is the most common early symptom. Impaired blood flow, poor vascularization, and muscle loss contribute to reduced lower limb strength and functional capacity, which are associated with higher morbidity and mortality. Walking exercises is a cornerstone of PAD management, particularly for patients with no or mild symptoms, making the assessment of lower limb strength and mobility essential for designing rehabilitation programs. The 30-second sit-to-stand test is a validated and practical measure of functional capacity and walking ability. Tele-assessment using video technology has been shown to be feasible and reliable in other patient populations. Although tele-rehabilitation has been widely studied and shown to improve functional outcomes, research on tele-assessment methods to accurately evaluate patient performance and the effectiveness of rehabilitation programs is still limited, particularly in PAD patients. This study aims to examine the reliability of the 30-second sit-to-stand test when performed via tele-assessment compared with face-to-face evaluation in patients with PAD.

Conditions

Peripheral Arterial Disease

Keywords

peripheral arterial disease; telemedicine; Remote Consultation; Physical Functional Performance

Outcome Measures

Primary Outcomes (1)

• Lower Extremity Function

  Lower extremity strength and functional mobility will be evaluated using the 30-second sit-to-stand test. Participants will sit on a 44 cm high chair with a backrest and no armrests, arms crossed over the shoulders, and will be instructed to stand and sit as many times as possible within 30 seconds. The number of complete repetitions will be recorded.

  From February 2026 to June 2026

Secondary Outcomes (5)

• Perceived Fatigue Response to 30 Second Sit-to-Stand Test

  February 2026 to June 2026

• Dyspnea Response to 30 Second Sit-to-Stand Test

  February 2026 to June 2026

• Heart Rate Response to 30 Second Sit-to-Stand Test

  February 2026 to June 2026

• Blood Pressure

  February 2026 to June 2026

• Oxygen Saturation

  February 2026 to June 2026

Study Arms (1)

Peripheral Arterial Disease

This cohort includes adult patients diagnosed with peripheral artery disease. Participants will undergo a single assessment of lower extremity function using the 30-second sit-to-stand test, performed both face-to-face and via tele-assessment.

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Patients diagnosed with peripheral artery disease, aged 18 to 65 years.

You may qualify if:

• Aged between 18 and 65 years
• Diagnosed with peripheral artery disease, Fontaine stage I-II, confirmed by peripheral angiography or Doppler ultrasonography
• Willingness to participate in the study
• Access to a smartphone and the internet

You may not qualify if:

• Presence of orthopedic, neurological, or psychological conditions that limit physical activity
• Neurological or musculoskeletal disorders affecting standing or walking
• History of ischemic amputation
• Acute inflammatory condition
• Use of walking aids
• Visual or hearing impairment
• Vestibular system disorder
• Cognitive impairment affecting cooperation
• Severe cardiopulmonary diseases limiting walking ability
• Major surgery or myocardial infarction within the last three months
• Unstable coronary artery disease

Sponsors & Collaborators

• Izmir Democracy University: lead

Study Sites (1)

Dokuz Eylul University Faculty of Medicine

Izmir, Balçova, 35330, Turkey (Türkiye)

RECRUITING

Related Publications (3)

• Zischke C, Simas V, Hing W, Milne N, Spittle A, Pope R. The utility of physiotherapy assessments delivered by telehealth: A systematic review. J Glob Health. 2021 Dec 18;11:04072. doi: 10.7189/jogh.11.04072. eCollection 2021.

  PMID: 34956637 BACKGROUND

• Bowman A, Denehy L, Benjemaa A, Crowe J, Bruns E, Hall T, Traill A, Edbrooke L. Feasibility and safety of the 30-second sit-to-stand test delivered via telehealth: An observational study. PM R. 2023 Jan;15(1):31-40. doi: 10.1002/pmrj.12783. Epub 2022 Mar 22.

  PMID: 35138036 BACKGROUND

• Aktan R, Yilmaz H, Demir I, Ozalevli S. Agreement between tele-assessment and face-to-face assessment of 30-s sit-to-stand test in patients with type 2 diabetes mellitus. Ir J Med Sci. 2023 Oct;192(5):2173-2178. doi: 10.1007/s11845-022-03238-w. Epub 2022 Dec 2.

  PMID: 36456718 BACKGROUND

MeSH Terms

Conditions

Peripheral Arterial Disease

Condition Hierarchy (Ancestors)

Atherosclerosis; Arteriosclerosis; Arterial Occlusive Diseases; Vascular Diseases; Cardiovascular Diseases; Peripheral Vascular Diseases

Central Study Contacts

Hazal Yakut Ozdemir, PhD

CONTACT

+9005074825877; hazal.yakutozdemir@idu.edu.tr

Cemre Emir, MSc

CONTACT

+9005453405480; cemre.emir@idu.edu.tr

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: CROSS SECTIONAL
• Target Duration: 1 Day
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor

Study Record Dates

• First Submitted: March 9, 2026
• First Posted: March 27, 2026
• Study Start: February 10, 2026
• Primary Completion: June 1, 2026
• Study Completion (Estimated): July 1, 2026
• Last Updated: March 27, 2026

Record last verified: 2026-03

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)