Mesh Infection After Hernioplasty: Complete vs Partial Removal - Retrospective Study on Outcomes and Pathogen Analysis
A Retrospective Study: Complete vs Partial Mesh Removal for Mesh Infection After Hernioplasty - Clinical Outcomes and Pathogen Analysis
1 other identifier
observational
100
0 countries
N/A
Brief Summary
Background: Mesh infection after tension-free inguinal hernia repair (IHR) is rare and challenging. When conservative treatment fails, surgery is often required. This study compared clinical outcomes of complete versus partial mesh removal in affected patients. Materials and Methods: We retrospectively analyzed patients who underwent surgery for mesh infection after IHR in our hospital between January 2016 and December 2025. Baseline data, perioperative indicators, postoperative complications, and microbiological results were compared between the complete and partial removal groups.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for all trials
Started Mar 2026
Shorter than P25 for all trials
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
March 18, 2026
CompletedStudy Start
First participant enrolled
March 18, 2026
CompletedFirst Posted
Study publicly available on registry
March 24, 2026
CompletedPrimary Completion
Last participant's last visit for primary outcome
May 31, 2026
ExpectedStudy Completion
Last participant's last visit for all outcomes
July 31, 2026
March 24, 2026
March 1, 2026
2 months
March 18, 2026
March 18, 2026
Conditions
Keywords
Outcome Measures
Primary Outcomes (2)
Hernia Recurrence Rate
Presence of clinically or radiologically confirmed recurrent inguinal hernia at the site of previous hernioplasty following mesh removal surgery.
From date of surgery to December 2025
Infection Recurrence Rate
Recurrence of surgical site infection at the same location after initial surgical treatment for mesh infection, confirmed by clinical signs (e.g., erythema, purulent drainage, sinus tract formation) and/or positive microbiological culture.
From date of surgery to December 2025
Study Arms (2)
The complete mesh removal group
The partial mesh removal group
Interventions
Total explantation of the entire prosthetic mesh, including all visible portions and fixation sutures, regardless of the extent of infection.
Excision of only the infected or non-incorporated portion of the mesh, with preservation of the well-incorporated, uninfected segment left in situ.
Eligibility Criteria
The study population consists of patients who developed mesh infection after tension-free inguinal hernioplasty and subsequently underwent surgical mesh removal (either complete or partial) at our institution. Data were collected retrospectively from medical records, including demographic characteristics, comorbidities, laboratory and imaging results, primary hernia surgery details, infection characteristics, intraoperative data, and postoperative outcomes. Follow-up was conducted through outpatient visits and telephone interviews, with the last follow-up on October 30, 2025.
You may qualify if:
- Patients who underwent tension-free inguinal hernioplasty with mesh placement.
- Patients diagnosed with mesh infection requiring surgical re-intervention.
- Patients who underwent complete or partial mesh removal surgery.
- Availability of complete medical records and follow-up data.
You may not qualify if:
- Patients with mesh infection managed conservatively (without surgical removal).
- Patients with missing critical data (e.g., intraoperative findings, pathogen results, or follow-up).
- Patients with concomitant procedures that could confound outcomes (e.g., simultaneous other hernia repair).
- Patients lost to follow-up immediately after discharge (no postoperative assessment).
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Fudan Universitylead
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- RETROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Director
Study Record Dates
First Submitted
March 18, 2026
First Posted
March 24, 2026
Study Start
March 18, 2026
Primary Completion (Estimated)
May 31, 2026
Study Completion (Estimated)
July 31, 2026
Last Updated
March 24, 2026
Record last verified: 2026-03
Data Sharing
- IPD Sharing
- Will not share