Modified vs. Conventional Laparoscopic TAPP for Inguinal Hernia

NCT07373314 | Not Yet Recruiting

• 1 other identifier: Exp132
• Study Type: interventional
• Target: 60
• Locations: 0 countries
• Sites: N/A

Brief Summary

This study aims to compare the outcomes of two laparoscopic techniques for repairing inguinal hernias: the modified tumescent technique (MT-TAPP) and the conventional laparoscopic transabdominal preperitoneal technique (CL-TAPP). The primary goal is to determine which technique provides better outcomes in terms of operative time, ease of pre-peritoneal space dissection, postoperative pain, and the formation of seromas. The study will involve 60 patients diagnosed with unilateral inguinal hernias, randomly assigned to either group. Participants in Group A will undergo the MT-TAPP procedure, which involves pre-peritoneal infiltration of a local anesthetic solution to improve dissection and reduce pain. Group B will undergo the standard CL-TAPP procedure. Data will be collected on various outcome measures and analyzed to identify which technique leads to quicker recovery, less postoperative pain, and fewer complications. The results of this study will help guide surgical decisions and improve patient outcomes in inguinal hernia repair.

Conditions

Inguinal Hernia Repair

Outcome Measures

Primary Outcomes (2)

• Pain Score

  A score of 0 represents no pain, while a score of 10 represents the worst pain.

  Recorded 24 hours post-surgery.

• Seroma Formation:

  Presence or absence of seroma, assessed during the 7-day postoperative follow-up.

Study Arms (2)

Modified Tumescent Laparoscopic TAPP (MT-TAPP)

EXPERIMENTAL

Other: Modified Tumescent Laparoscopic TAPP (MT-TAPP) for the first group.

Conventional Laparoscopic TAPP (CL-TAPP)

ACTIVE COMPARATOR

Other: Conventional Laparoscopic TAPP (CL-TAPP)

Interventions

Conventional Laparoscopic TAPP (CL-TAPP) OTHER

In this intervention, participants will undergo the conventional laparoscopic transabdominal preperitoneal (TAPP) hernia repair. This standard technique involves placing three ports to access the inguinal region, followed by dissection of the pre-peritoneal space and placement of a mesh to repair the hernia. The conventional method does not use tumescent infiltration and relies solely on the surgeon's skill to navigate the anatomical structures. This approach is well-established and commonly used in inguinal hernia repairs, but it may be associated with longer operative times and more postoperative pain compared to the modified technique.

Conventional Laparoscopic TAPP (CL-TAPP)

Modified Tumescent Laparoscopic TAPP (MT-TAPP) for the first group. OTHER

In this intervention, participants will undergo laparoscopic inguinal hernia repair using the modified tumescent technique. This technique involves pre-peritoneal infiltration of a solution containing lidocaine, epinephrine, and saline. The tumescent solution is injected into the peritoneum to create a "tumescent" effect, making the tissues easier to dissect and reducing bleeding. This approach aims to improve surgical visibility, reduce operative time, minimize postoperative pain, and shorten the learning curve for less experienced surgeons. The rest of the procedure follows the standard laparoscopic TAPP repair, with mesh placement and peritoneal closure.

Modified Tumescent Laparoscopic TAPP (MT-TAPP)

Eligibility Criteria

• Age: 18 Years - 50 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Age: 18 to 50 years.
• Gender: Both male and female participants.
• Condition: Diagnosed with unilateral inguinal hernia (as per operational definition).
• Health Status: ASA I-III (American Society of Anesthesiologists physical status classification), indicating that the patient is fit for surgery.
• Consent: Participants must be able to provide informed consent to participate in the study.

You may not qualify if:

• Femoral Hernias.
• Incarcerated or Strangulated Hernia.
• Recurrent Hernias (as per medical record).
• Serious Systemic Diseases:
• Conditions such as heart failure or coagulation problems (e.g., PT \> 15 sec).
• ASA III-V classification, indicating a higher risk for surgery.
• Pregnancy (if applicable).
• Allergy to Anesthesia or the substances used in the tumescent solution (lidocaine, epinephrine, saline).
• Uncontrolled Diabetes or other medical conditions that might interfere with the healing process.

Sponsors & Collaborators

• University of Health Sciences Lahore: lead

Central Study Contacts

Dr. Taseen Imran

CONTACT

923045079008; taseenimran5@gmail.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: January 13, 2026
• First Posted: January 28, 2026
• Study Start: February 10, 2026
• Primary Completion (Estimated): August 15, 2026
• Study Completion (Estimated): August 30, 2026
• Last Updated: January 28, 2026

Record last verified: 2026-01

Data Sharing

• IPD Sharing: Will not share