NCT07484737

Brief Summary

This randomized controlled trial aims to assesses the combined effects of MWM and tendon gliding exercises on hand function in smartphone users with De Quervain's Tenosynovitis, considering hand anthropometric variations.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
44

participants targeted

Target at P25-P50 for not_applicable

Timeline
0mo left

Started Feb 2026

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress91%
Feb 2026Jun 2026

Study Start

First participant enrolled

February 20, 2026

Completed
24 days until next milestone

First Submitted

Initial submission to the registry

March 16, 2026

Completed
4 days until next milestone

First Posted

Study publicly available on registry

March 20, 2026

Completed
1 month until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2026

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2026

Expected
Last Updated

March 27, 2026

Status Verified

March 1, 2026

Enrollment Period

2 months

First QC Date

March 16, 2026

Last Update Submit

March 25, 2026

Conditions

Keywords

Mulligan's Mobilization with MovementTendon Gliding ExercisesHand AnthropometryDequeverian tenosynovitis

Outcome Measures

Primary Outcomes (3)

  • Grip Strength Dynamometer

    It is a valid and reliable tool used for measuring isometric hand grip strength. This objective tool will be used to assess hand muscular performance and functional status in patients with De Quervain's Tenosynovitis. The NOD digital dynamometer has been shown to provide consistent and reproducible readings. Reliability: 0.97 and Validity: 0.94.

    4 weeks

  • Patient-Rated Wrist Evaluation (PRWE) Questionnaire

    It is a valid and reliable patient-reported outcome measure for assessing wrist pain and functional disability. This tool will be used to evaluate wrist-related limitations in activities of daily living in DQT patients. It includes two subscales: pain and function, making it responsive to clinical changes. Reliability: 0.96 and Validity: 0.88.

    4 weeks

  • Hand Anthropometry (Caliper & Measuring Tape)

    These are reliable and valid tools used to measure various hand dimensions, including palm width, thumb length, and wrist circumference. These measurements help understand the influence of hand morphology on grip strength and functional ability in smartphone users with DQT. Reliability: 0.88 and Validity: 0.71.

    Baseline

Study Arms (2)

Mulligan's Mobilization with Movement (MWM) + Tendon Gliding Exercises (combined effect)

EXPERIMENTAL

MWM: Radial glide of 1st MCP with active thumb extension (10 reps × 3 sets, progressed with resistance in weeks 3-4). 2- Tendon Gliding Exercises: Straight hand, hook fist, tabletop, full fist, straight fist (10 reps × 2 sets in weeks 1-2; 3 sets × 15 with resistance band in weeks 3

Other: MWM + Tendon Gliding Exercises

Conventional Treatment

OTHER

Wrist ROM (flexion, extension, radial/ulnar deviation, pronation/supination). 2-Thumb ROM (abduction/adduction, flexion/extension, opposition/circumduction). 3-Isometric wrist/thumb strengthening. 4-Strengthening with soft ball, thumb abduction/adduction against resistance. 5-Postural and ergonomic education for smartphone usage.

Other: Conventional Treatment

Interventions

MWM: Radial glide of 1st MCP with active thumb extension (10 reps × 3 sets, progressed with resistance in weeks 3-4). 2- Tendon Gliding Exercises: Straight hand, hook fist, tabletop, full fist, straight fist (10 reps × 2 sets in weeks 1-2; 3 sets × 15 with resistance band in weeks 3-4).

Mulligan's Mobilization with Movement (MWM) + Tendon Gliding Exercises (combined effect)

1- Wrist ROM (flexion, extension, radial/ulnar deviation, pronation/supination). 2-Thumb ROM (abduction/adduction, flexion/extension, opposition/circumduction). 3-Isometric wrist/thumb strengthening. 4-Strengthening with soft ball, thumb abduction/adduction against resistance. 5-Postural and ergonomic education for smartphone usage

Conventional Treatment

Eligibility Criteria

Age18 Years - 25 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Patient diagnosed with De Quervain's Tenosynovitis (positive Finkelstein's test).
  • Patient having persistent thumb/wrist pain and functional difficulties for a duration of at-least 2 weeks.
  • Patient willing to participate and give informed consent.

You may not qualify if:

  • Patient with history of trauma, fracture, or surgery in the affected wrist or thumb.
  • Patient with neurological disorder affecting the upper limb.
  • Patient with systemic conditions like rheumatoid arthritis or diabetes affecting tendon function.
  • Any other co-morbidity.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Begum Akhtar Rukhsana Hospital (stroke and rehab centre)

Rawalpindi, Punjab Province, Pakistan

RECRUITING

Study Officials

  • Maria khalid, MSOMPT

    Riphah International University

    PRINCIPAL INVESTIGATOR

Central Study Contacts

maria Khalid, MSOMPT

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 16, 2026

First Posted

March 20, 2026

Study Start

February 20, 2026

Primary Completion

May 1, 2026

Study Completion (Estimated)

June 1, 2026

Last Updated

March 27, 2026

Record last verified: 2026-03

Data Sharing

IPD Sharing
Will not share

Locations