NCT07484451

Brief Summary

This randomized controlled trial aims to compare the effects of Strategy Training and Proprioceptive Neuromuscular Facilitation (PNF) on balance, gait, and functional independence in patients with Parkinson's disease. Parkinson's disease leads to impaired motor function, reduced balance, and decreased independence. Physiotherapy interventions such as strategy-based training and PNF may help improve mobility and functional performance. Participants will be randomly assigned to two groups: one receiving Strategy Training and the other receiving PNF intervention. Outcome measures including balance tests, gait assessment, and functional independence scales will be evaluated before and after treatment. The study aims to determine which intervention is more effective in improving functional outcomes in Parkinson's disease patients.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
42

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Mar 2026

Shorter than P25 for not_applicable

Geographic Reach
1 country

2 active sites

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

March 1, 2026

Completed
15 days until next milestone

First Submitted

Initial submission to the registry

March 16, 2026

Completed
4 days until next milestone

First Posted

Study publicly available on registry

March 20, 2026

Completed
1 month until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2026

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

May 1, 2026

Completed
Last Updated

March 20, 2026

Status Verified

March 1, 2026

Enrollment Period

2 months

First QC Date

March 16, 2026

Last Update Submit

March 16, 2026

Conditions

Keywords

Parkinson's disease, PNF, strategy-based training, ADLs

Outcome Measures

Primary Outcomes (6)

  • 10-Meter Walk Test (10MWT)

    The 10-Meter Walk Test (10MWT) is an effective instrument that is applied to determine the walking speed and functional mobility in different populations.

    6 weeks

  • Tandem Stance Test

    Tandem Stance Test is one of the essential clinical tests of balance and postural stability particularly among older adults. It involves getting a person to stand on their heels to toes and this is used to determine people who are at risk of falling.

    6 weeks

  • Pastor Test (Shoulder Tug)

    Pastor Test (Shoulder Tug test) is a test used to determine the shoulder stability (especially the anterior shoulder instability). In the test, the examiner pulls the patient using his arm as he keeps the shoulder constant to reveal too much movement or pain.

    6 weeks

  • 30 sec Chair Test

    30 sec Chair Test; A popular test for assessing lower body strength, balance, and functional mobility especially in older adults is the chair test. It gauges a person's capacity to carry out daily tasks on their own by timing how long it takes them to get up from a sitting position and sit down again.

    6 weeks

  • Retropulsion Test

    Retropulsion Test is a clinical examination, which is mainly applied to determine the postural stability and balance in a person, particularly the people with Parkinson disease. In this test, the examiner smoothly pulls the shoulders of the patient in the standing position where the patient stands in a relaxed position, and the examiner sees whether the patient can balance or not.

    6 weeks

  • Unified Parkinson's Disease Rating Scale (UPDRS)

    Unified Parkinson Disease Rating Scale (UPDRS) as one of the important assessment instruments in the study of Parkinson disease and its clinical application. (UPDRS) scale is a comprehensive tool, employed to assess treatment issues related to the treatment of the Parkinson disease, the daily life activities as well as the motor and non-motor symptoms.

    6 weeks

Study Arms (2)

Group A: PNF Technique

EXPERIMENTAL

Participants will undergo PNF techniques targeting the muscles involved in balance and gait. This may include diagonal patterns, facilitation techniques, and proprioceptive neuromuscular facilitation holds.

Other: PNF Technique

Group B: Strategy training

EXPERIMENTAL

Strategy Training Group Participants will receive training in specific cognitive strategies to improve balance and gait. This will include visual cues, verbal instructions, and mental rehearsal techniques.

Other: Strategy Training

Interventions

Participants will undergo PNF techniques targeting the muscles involved in balance and gait. This may include diagonal patterns, facilitation techniques, and proprioceptive neuromuscular facilitation holds.

Group A: PNF Technique

Strategy Training Group Participants will receive training in specific cognitive strategies to improve balance and gait. This will include visual cues, verbal instructions, and mental rehearsal techniques.

Group B: Strategy training

Eligibility Criteria

Age40 Years - 80 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Global hospital and dialysis center Lahore

Lahore, Punjab Province, 54000, Pakistan

Location

Majid medical complex Lahore

Lahore, Punjab Province, 54000, Pakistan

Location

MeSH Terms

Conditions

Parkinson Disease

Condition Hierarchy (Ancestors)

Parkinsonian DisordersBasal Ganglia DiseasesBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesMovement DisordersSynucleinopathiesNeurodegenerative Diseases

Study Officials

  • Arnab Altaf, MS-PT

    Riphah International University

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 16, 2026

First Posted

March 20, 2026

Study Start

March 1, 2026

Primary Completion

May 1, 2026

Study Completion

May 1, 2026

Last Updated

March 20, 2026

Record last verified: 2026-03

Locations