Evaluating the Effectiveness of Postoperative Analgesic Methods in Thoracotomy Cases

NCT07482449 | Completed

• 1 other identifier: TUTF-GOBAEK 2023/190
• Study Type: observational
• Target: 72
• Locations: 1 country
• Sites: 1

Brief Summary

Effective control of severe post-thoracotomy pain is pivotal for minimizing pulmonary complications and enhancing patient comfort. This prospective, randomized, three-arm study compared the analgesic efficacy of ultrasound-guided bilateral erector spinae plane block (ESPB) and thoracic epidural analgesia (TEA) with conventional intravenous opioid-based care. Seventy-two ASA I-II patients aged 18-80 years undergoing elective thoracotomy were block-randomized to receive TEA, ESPB, or no regional intervention (control). All procedures were performed at the end of surgery before emergence from anesthesia. Pain intensity was assessed at 1, 2, 4, 6, 12, and 24 h postoperatively using the Visual Analog Scale (VAS). Additional outcomes included time to first rescue opioid, total tramadol consumption, time to modified Aldrete score (MAS) ≥ 9, patient satisfaction, and length of hospital stay.

Conditions

Thoracotomy Analgesia

Outcome Measures

Primary Outcomes (1)

• Comparison of the analgesic efficacy of regional techniques

  The analgesic efficacy of TEA and ESP blocks after thoracotomy surgeries was evaluated at 1, 2, 4, 6, 12, and 24 hours postoperatively in terms of VAS scores and analgesic drug consumption. The frequency and amount of tramadol and fentanyl analgesic drug consumption were recorded in the postoperative period. VAS scores were monitored at the specified times. The results were compared, and analgesic efficacy was evaluated. In addition, patient satisfaction (1: excellent, 2: good, 3: moderate, 4: poor), intensive care unit and hospital stay, and postoperative recovery time (using the modified aldarate score) were evaluated.

  THE FIRST 24 HOURS AFTER THORACOTOMY SURGERY

Study Arms (3)

TEA ANALGESİA

PATIENTS WHO UNDERWENT TEA AFTER THORACOTOMY CASES

TEA BLOCK

ATIENTS RECEIVING INTRAVENOUS ANALGESIA AFTER THORACOTOMY CASES

İV ANALGESİA

PATIENTS RECEIVING INTRAVENOUS ANALGESICS AFTER THORACOTOMY CASES

Eligibility Criteria

• Age: 18 Years - 80 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

patients who will undergo thoracotomy surgery

Sponsors & Collaborators

• Denizhan Acar: lead

Study Sites (1)

Trakya University Faculty of Medicine Hospital

Edirne, Merkez, 22020, Turkey (Türkiye)

Location

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: PROSPECTIVE
• Target Duration: 1 Day
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: research assistant doctor

Study Record Dates

• First Submitted: March 10, 2026
• First Posted: March 19, 2026
• Study Start: May 8, 2023
• Primary Completion: May 20, 2025
• Study Completion: February 12, 2026
• Last Updated: March 23, 2026

Record last verified: 2026-03

Locations

TU (1)