NCT07482410

Brief Summary

Knee osteoarthritis is similarly to the arthritis of the hip which is due to the degeneration of the cartilagre due to wear and tear forces on the knee joint. The aim of the study is to investigate the combined effects of active release and feldenkrais exercises on pain, range of motion and functional disability of patients with knee osteoarthritis.

Trial Health

55
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
40

participants targeted

Target at P25-P50 for not_applicable knee-osteoarthritis

Timeline
Completed

Started Feb 2025

Geographic Reach
1 country

1 active site

Status
active not recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 15, 2025

Completed
1 year until next milestone

First Submitted

Initial submission to the registry

February 23, 2026

Completed
20 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 15, 2026

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

March 15, 2026

Completed
4 days until next milestone

First Posted

Study publicly available on registry

March 19, 2026

Completed
Last Updated

March 19, 2026

Status Verified

March 1, 2026

Enrollment Period

1.1 years

First QC Date

February 23, 2026

Last Update Submit

March 16, 2026

Conditions

Keywords

Knee OsteoarthritisActive release techniqueFeldenkrais exercisedisabilityPainrange of motion

Outcome Measures

Primary Outcomes (2)

  • Numerical Pain Rating Scale (NPRS)

    Patient level of pain will be assessed using this scale. This scale ranges from 0 to 10. 0 indicates "no pain" and 10 indicates "worst pain". NPRS have shown high test-retest reliability (r = 0.96 and 0.95, respectively).

    8 weeks

  • Universal Goniometer (UG)

    The range of motion will be measured using universal goniometer that has an inter-rater reliability (ICC2, 2 = 0.79 to 0.92) for knee osteoarthritis.

    8 weeks

Study Arms (2)

Active release and feldenkrais exercises along with standard physical therapy.

ACTIVE COMPARATOR

Patients will receive active release and feldenkrais exercises along with standard physical therapy treatment. Standardized Physiotherapy treatment: * Hot pack for 10 minutes and * TENS for 10 minutes * Hamstring stretching * Quadriceps strengthening * Squat release exercises

Other: Active release and feldenkrais exercises along with standard physical therapy.

Active release exercises and standard physical therapy treatment.

OTHER

Patients will receive active release exercises and standard physical therapy treatment. Standardized Physiotherapy treatment: * Hot pack for 10 minutes and * TENS for 10 minutes * Hamstring stretching * Quadriceps strengthening * Squat release exercises

Other: Active release and feldenkrais exercises along with standard physical therapy.

Interventions

Patients will receive active release and feldenkrais exercises for 3 sessions per week for the total of 6 weeks each exercise 10 repetitions and 2 sets.

Active release and feldenkrais exercises along with standard physical therapy.Active release exercises and standard physical therapy treatment.

Eligibility Criteria

Age40 Years - 60 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Both genders with age between 40-60 with knee osteoarthritis.
  • BMI 25-29.9
  • Knee pain 3-7 on NPRS
  • degree decrease in knee flexion range

You may not qualify if:

  • Patient who used any corticosteroid injection during last six months.
  • Patients who had any joint infection.
  • Previous knee surgery.
  • Grade 4/ advanced knee osteoarthritis

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Naseer Hospital

Lahore, Punjab Province, 56700, Pakistan

Location

MeSH Terms

Conditions

Osteoarthritis, KneePain

Condition Hierarchy (Ancestors)

OsteoarthritisArthritisJoint DiseasesMusculoskeletal DiseasesRheumatic DiseasesNeurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • Faiza Taufiq, MSPT

    Riphah International University

    PRINCIPAL INVESTIGATOR
  • Faiza Taufiq

    Riphah International University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Model Details: Participants received active release technique and feldenkrais exercises along with standard physical therapy and mulligan mobilization.
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

February 23, 2026

First Posted

March 19, 2026

Study Start

February 15, 2025

Primary Completion

March 15, 2026

Study Completion

March 15, 2026

Last Updated

March 19, 2026

Record last verified: 2026-03

Locations