Assessment of Malnutrition in Hospitalized Patients: a Quasi Study

NCT07473492 | Not Yet Recruiting

• 2 other identifiers: hospitalized malnutritionAMMRP-2026-BASRA
• Study Type: observational
• Target: 300
• Locations: 0 countries
• Sites: N/A

Brief Summary

Malnutrition among hospitalized patients is a critical, yet often overlooked, public health issue associated with increased complications, longer hospital stays, higher mortality, and greater healthcare costs. In Iraq, factors such as dietary patterns, the burden of chronic diseases, and healthcare constraints may increase the risk of hospital-acquired malnutrition. Current standard care may not include systematic nutritional screening or protocol-driven support. This trial aims to test whether implementing an individualized nutritional support program can improve clinical outcomes for at-risk medical inpatients in Iraqi hospitals, building upon evidence from international studies

Conditions

COPD , Neurology , ICU; Alzheimer; Alzheimer s Disease

Keywords

Hospital Malnutrition , Nutritional Risk Screening ,GLIM Criteria; Medication-Related Problems (MRPs

Outcome Measures

Primary Outcomes (2)

• oint Prevalence of Malnutrition using GLIM Criteria and NRS-2002

  The primary goal is to determine the prevalence of malnutrition among hospitalized adult patients in Al-Basrah Teaching Hospital and Al-Fayhaa General Hospital. All participants are first screened using the Nutritional Risk Screening (NRS-2002). For those identified as "at risk" (score $\\ge$ 3), a definitive diagnosis is made using the Global Leadership Initiative on Malnutrition (GLIM) criteria. Diagnosis requires at least one phenotypic criterion (non-volitional weight loss, low BMI, or reduced muscle mass) and one etiologic criterion (reduced food intake/malabsorption or disease-related inflammation/chronic illness, such as COPD or critical illness in the Neurology ICU). The prevalence will be reported as the percentage of the total cohort meeting the GLIM diagnostic threshold.

  Within 48 hours of hospital admission

• Point Prevalence of Malnutrition using GLIM Criteria , NRS2002

  The primary goal is to determine the prevalence of malnutrition among hospitalized adult patients in Al-Basrah Teaching Hospital and Al-Fayhaa General Hospital. All participants are first screened using the Nutritional Risk Screening (NRS-2002). For those identified as "at risk" (score $\\ge$ 3), a definitive diagnosis is made using the Global Leadership Initiative on Malnutrition (GLIM) criteria. Diagnosis requires at least one phenotypic criterion (non-volitional weight loss, low BMI, or reduced muscle mass) and one etiologic criterion (reduced food intake/malabsorption or disease-related inflammation/chronic illness, such as COPD or critical illness in the Neurology ICU). The prevalence will be reported as the percentage of the total cohort meeting the GLIM diagnostic threshold.

  Within 48 hours of hospital admission.

Study Arms (1)

Hospitalized Adults in Basrah

This cohort consists of 200 adult patients (age \> 18 years) admitted to the Medicine, Surgery, and Neurology ICU wards of Al-Basrah Teaching Hospital and Al-Fayhaa General Hospital.

Other: Nutritional Assessment and Medication Review

Interventions

Nutritional Assessment and Medication Review OTHER

Intervention Description"This observational intervention consists of a multi-disciplinary clinical assessment conducted in three distinct phases for each enrolled participant:Validated Two-Step Nutritional Evaluation: Unlike standard hospital screening, this study uses the Nutritional Risk Screening (NRS-2002) as an initial filter. Patients identified as 'at risk' (score $\\ge$ 3) are immediately subjected to the Global Leadership Initiative on Malnutrition (GLIM) criteria. This provides a definitive diagnosis by combining phenotypic criteria (non-volitional weight loss, low BMI, or reduced muscle mass) with etiologic criteria (reduced food intake/malabsorption or disease-related inflammation/chronic illness).Specialized Comorbidity Analysis: The assessment specifically targets the impact of Chronic Obstructive Pulmonary Disease (COPD) and Alzheimer's Disease on nutritional status, evaluating how respiratory hypermetabolism and cognitive impairment act as independent drivers of malnutri

Also known as: NRS-2002 and GLIM-based Nutritional Assessment, Point Prevalence Malnutrition Screening

Hospitalized Adults in Basrah

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The study population consists of hospitalized adult patients admitted to Al-Basrah Teaching Hospital and Al-Fayhaa General Hospital in Basra, Iraq. The cohort primarily includes individuals admitted to the Medical wards, Surgical wards, and the Neurology Intensive Care Unit (ICU). This population represents a diverse clinical spectrum, with a particular focus on patients suffering from chronic inflammatory conditions and neurodegenerative disorders, specifically Chronic Obstructive Pulmonary Disease (COPD) and Alzheimer's Disease. The population is characterized by varying levels of nutritional risk and complex pharmacotherapy regimens (polypharmacy). Participants are recruited within the first 48 hours of admission to capture point-prevalence data. The demographic includes both males and females aged 18 years and older, representing the urban and suburban population served by the Basra Health Directorate.

You may qualify if:

• Age: Adult patients aged $\\ge$ 18 years.Setting: Patients admitted to the Medicine, Surgery, or Neurology Intensive Care Unit (ICU) wards at Al-Basrah Teaching Hospital or Al-Fayhaa General Hospital.Duration of Stay: Patients who have been hospitalized for a minimum of 48 hours (to ensure a baseline for malnutrition screening and medication review).Clinical Conditions: Patients with various primary diagnoses, including specific subgroups with Chronic Obstructive Pulmonary Disease (COPD) and Alzheimer's Disease.Informed Consent: Patients or their legal guardians (especially for those in the ICU or with cognitive impairment) who provide written or verbal informed consent.

You may not qualify if:

• Maternity/Obstetrics: Pregnant or lactating women, as nutritional requirements and physiological BMI changes differ from the general adult population.
• Terminal Illness: Patients in end-of-life or palliative care where nutritional intervention is no longer a clinical goal.
• Incomplete Records: Patients with missing medical or medication charts that prevent the accurate identification of Medication-Related Problems (MRPs).
• Short Stay: Patients planned for discharge or transfer within less than 48 hours of admission.
• Psychiatric Disorders: Patients with primary psychiatric diagnoses that may interfere with the ability to conduct nutritional assessments (unless a guardian is present).

Sponsors & Collaborators

• AlFayhaa General Hospital: lead
• University of Basrah: collaborator
• Ministry of Health, Iraq: collaborator

Related Publications (1)

• Azzolino D, Lucchi T. Malnutrition in older adults: a wider view. Lancet. 2023 Nov 25;402(10416):1976. doi: 10.1016/S0140-6736(23)01780-4. No abstract available.

  PMID: 38007257 BACKGROUND

Related Links

• The leading international body for clinical nutrition. This link provides the guidelines for the NRS-2002 screening tool and nutrition in the ICU, which are the foundations of the AMMRP protocol.

MeSH Terms

Conditions

Pulmonary Disease, Chronic Obstructive

Interventions

Nutrition Assessment; Medication Review

Condition Hierarchy (Ancestors)

Lung Diseases, Obstructive; Lung Diseases; Respiratory Tract Diseases; Chronic Disease; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Data Collection; Epidemiologic Methods; Investigative Techniques; Health Care Evaluation Mechanisms; Quality of Health Care; Health Care Quality, Access, and Evaluation; Epidemiologic Measurements; Public Health; Environment and Public Health; Medication Systems; Organization and Administration; Health Services Administration; Patient Care Management

Central Study Contacts

mawj ali Principal Investigator, College of Pharmacy, University of Bas, BPharm

CONTACT

+9647705746266; mawjali92@gmail.com

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: CROSS SECTIONAL
• Target Duration: 1 Month
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: March 11, 2026
• First Posted: March 16, 2026
• Study Start: April 1, 2026
• Primary Completion (Estimated): August 1, 2026
• Study Completion (Estimated): September 1, 2026
• Last Updated: March 16, 2026

Record last verified: 2026-03