Post-Hoc Cost-Utility Analysis of Ultrasound-Guided Erector Spinae Plane (ESP) Block Versus Total Intravenous Anesthesia (TIVA) in Posterior Scoliosis Correction Surgery: Evidence From the Egyptian EQ-5D-5L Value Set

NCT07470567 | Completed DMC

• 1 other identifier: NBH-ANES-PECON-0326-01
• Study Type: observational
• Target: 44
• Locations: 1 country
• Sites: 1

Brief Summary

Posterior scoliosis correction surgery is associated with sever postoperative pain that necessitate high perioperative opioid doses to alleviate pain . Regional anesthesia techniques such as ultrasound-guided erector spinae plane (ESP) block have emerged as promising strategies for improving postoperative analgesia and reducing opioid consumption. This secondary analysis evaluates the cost-utility of ESP block compared with total intravenous anesthesia (TIVA) alone in patients scheduled for posterior scoliosis correction surgery. The analysis assesses postoperative quality of life using the EQ-5D-5L instrument value sets from Egyptian population alongside healthcare costs within the early postoperative period. The study aims to determine whether ESP block provides improved patient outcomes and represents a cost-effective strategy for perioperative pain management in scoliosis surgery

Conditions

Scoliosis; Spine Deformity

Keywords

erector spinae plan block ,regional anesthesia ,postoperative pain ,cost utility analysis , EQ-5D-5L; erector spinae plan block; anesthesia; postoperative pain; cost utility analysis

Outcome Measures

Primary Outcomes (1)

• economic evaluation (cost utility analysis )of anesthesia (ESP block) compared with (TIVA) alone and the resulting consumption of health resources in patients scheduled for scoliosis correction from a healthcare payer pers

  To implement an economic evaluation (cost utility analysis) in addition to the evaluation of clinical effects in order to make rational decisions regarding the acceptance of new mode of anesthesia (ESP block) compared with total intravenous anesthesia (TIVA) alone and the resulting consumption of health resources in patients scheduled for scoliosis correction from a healthcare payer perspective.

  2 months

Study Arms (2)

ESP Block Group Group

Patients undergoing posterior scoliosis correction surgery who received ultrasound-guided erector spinae plane (ESP) block in addition to total intravenous anesthesia (TIVA) as part of multimodal perioperative analgesia. The ESP block was performed under ultrasound guidance prior to surgical incision to provide thoracic paraspinal analgesia

TIVA Control Group

Patients undergoing posterior scoliosis correction surgery who received total intravenous anesthesia (TIVA) without erector spinae plane block. Standard perioperative analgesia and anesthetic management were provided according to institutional protocol

Eligibility Criteria

• Age: 12 Years - 25 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64)
• Sampling Method: Probability Sample

Study Population

Patients aged 12-25 years diagnosed with scoliosis and scheduled for posterior spinal fixation surgery were included in the study. All participants were classified as ASA physical status I-III and underwent surgery under general anesthesia in the operating rooms .

You may qualify if:

• Patients aged 12-25 years,
• scheduled for posterior spinal fixation for scoliosis correction.
• ASA physical status I-III,

You may not qualify if:

• ASA status \> III,
• refusal to participate,
• multiple congenital anomalies,
• hypersensitivity or contraindication to study medications,
• and body weight \< 40 kg.

Sponsors & Collaborators

• National Bank Hospital: lead

Study Sites (1)

National Bank Hospital

Cairo, Katameya Road, Egypt

Location

MeSH Terms

Conditions

Scoliosis; Pain, Postoperative

Condition Hierarchy (Ancestors)

Spinal Curvatures; Spinal Diseases; Bone Diseases; Musculoskeletal Diseases; Postoperative Complications; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Pain; Neurologic Manifestations; Signs and Symptoms

Study Officials

• basma mohamed, master

  National bank hospital ,Cairo, Egypt

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: head of health economics unit

Study Record Dates

• First Submitted: March 10, 2026
• First Posted: March 13, 2026
• Study Start: October 15, 2025
• Primary Completion: January 15, 2026
• Study Completion: February 28, 2026
• Last Updated: March 16, 2026

Record last verified: 2026-03

Data Sharing

• IPD Sharing: Will not share

Locations

EG (1)