Impact of Visceral Adiposity on Postoperative Atrial Fibrillation After CABG
1 other identifier
observational
300
0 countries
N/A
Brief Summary
Obesity has become a major public health problem in both developed and developing countries, with a continuous increase particularly since the 1980s. Moreover, it is a well-established metabolic risk factor for diabetes mellitus, hypertension, and various types of cancer, as well as cardiovascular diseases such as heart failure and coronary artery disease. Body mass index (BMI) is calculated by dividing body weight in kilograms by the square of height in meters and is widely used as an indicator of obesity. However, BMI does not quantitatively reflect body fat distribution and fails to account for components such as skeletal muscle and bone mass. Therefore, interest in assessing body fat distribution has increased, and in recent years, studies evaluating the correlation between anthropometric, biochemical, and anatomical measurements and clinical outcomes have become more frequent. In particular, it is acknowledged that abdominal obesity cannot be accurately represented by BMI alone and is primarily associated with visceral adipose tissue (VAT). The aim of this study is to evaluate the association between preoperative visceral and subcutaneous adipose tissue measurements (VAT and SAT), assessed by ultrasonography in patients scheduled for open-heart surgery, and the development of postoperative atrial fibrillation.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Apr 2026
Shorter than P25 for all trials
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
March 8, 2026
CompletedFirst Posted
Study publicly available on registry
March 12, 2026
CompletedStudy Start
First participant enrolled
April 1, 2026
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 22, 2026
ExpectedStudy Completion
Last participant's last visit for all outcomes
January 22, 2027
March 12, 2026
March 1, 2026
9 months
March 8, 2026
March 8, 2026
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Effect of visceral adipose tissue thickness on postoperative atrial fibrillation
Preoperative ultrasound-guided measurement of visceral adipose tissue thickness will be performed. The association between visceral fat thickness and the development of postoperative atrial fibrillation will be evaluated.
Within 7 days after coronary artery bypass graft surgery or until hospital discharge
Study Arms (2)
Group 1: Postoperative AF Group
Visceral and subcutaneous adipose tissue thickness in patients who develop postoperative atrial fibrillation after coronary artery bypass graft surgery.
Group 2: Non-AF Group
Visceral and subcutaneous adipose tissue thickness in patients who do not develop postoperative atrial fibrillation after coronary artery bypass graft surgery.
Interventions
In patients undergoing coronary artery bypass graft surgery, ultrasound-guided measurements of visceral and subcutaneous adipose tissue will be performed preoperatively. The relationship between adipose tissue thickness and the development of postoperative atrial fibrillation will be evaluated by comparing patients who develop AF with those who do not.
In patients undergoing coronary artery bypass graft surgery, ultrasound-guided measurements of visceral and subcutaneous adipose tissue will be performed preoperatively. The relationship between adipose tissue thickness and the development of postoperative atrial fibrillation will be evaluated by comparing patients who develop AF with those who do not.
Eligibility Criteria
Adult patients (≥18 years) scheduled for coronary artery bypass graft surgery.
You may qualify if:
- Elective isolated coronary artery bypass graft surgery (on-pump)
- Age ≥18 years, planned prospectively in 300 patients
You may not qualify if:
- Patients requiring urgent or emergency surgery
- Off-pump coronary artery bypass graft surgery
- Surgeries other than isolated coronary artery bypass graft
- Patients in whom abdominal ultrasound measurement cannot be performed (e.g., due to severe deformity, wounds, edema)
- Active malignancy
- eGFR \<30 mL/min
- Advanced-stage chronic obstructive pulmonary disease (COPD)
- Preoperative atrial fibrillation or atrial flutter
- Patients who do not provide written informed consent for the study
Contact the study team to confirm eligibility.
Sponsors & Collaborators
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- OTHER
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER GOV
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Anesthesiology and Reanimation Specialist, M.D.
Study Record Dates
First Submitted
March 8, 2026
First Posted
March 12, 2026
Study Start
April 1, 2026
Primary Completion (Estimated)
December 22, 2026
Study Completion (Estimated)
January 22, 2027
Last Updated
March 12, 2026
Record last verified: 2026-03