Comparison of Two Sitting Durations During Saddle Anesthesia on Discharge Readiness in Perianal Surgery

NCT07466121 | Completed

• 1 other identifier: MS-665-2025
• Study Type: interventional
• Target: 66
• Locations: 1 country
• Sites: 1

Brief Summary

Most minor perianal surgeries are performed as day-case procedures requiring rapid recovery and effective symptom control. Saddle block anesthesia (SBA) provides reliable perineal anesthesia with minimal hemodynamic and motor effects, promoting faster recovery than general anesthesia. However, the duration of sitting after intrathecal injection influences anesthetic spread, and the optimal sitting time to balance adequate anesthesia with early discharge remains unclear.

Conditions

Saddle Block Anesthesia; Readiness of Discharge; Quality of Recovery (QoR-15)

Outcome Measures

Primary Outcomes (1)

• Time to readiness for discharge

  Patients will be considered ready for discharge when the modified Post Anaesthetic Discharge Scoring System (PADSS) \>9

  During the first 24 hour postoperatively

Secondary Outcomes (3)

• time to void

  from SBA till 24 hour postoperatively

• time to ambulation

  from SBA till 24 hour postoperatively

• quality of recovery

  at the end of 24 hour after surgery

Study Arms (2)

5-min group

ACTIVE COMPARATOR

Other: 5-min sitting duration after SBA

8-min group

ACTIVE COMPARATOR

Other: 8-min sitting duration after SBA

Interventions

5-min sitting duration after SBA OTHER

Patients will remain seated for 5 min after local anesthetic injection

5-min group

8-min sitting duration after SBA OTHER

Patients will remain seated for 8 min after local anesthetic injection

8-min group

Eligibility Criteria

• Age: 21 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Adult patients (21-65 years), ASA I-III undergoing perianal surgery.

You may not qualify if:

• Severe cardiac morbidities (impaired contractility with ejection fraction \< 40%, heart block, arrhythmias, tight valvular lesions)
• Contraindication to neuraxial anesthesia such as coagulopathy and local infection
• Pregnant or lactating women,
• Allergy of any of the study drugs

Sponsors & Collaborators

• Cairo University: lead

Study Sites (1)

Cairo University

Cairo, Cairo Governorate, Egypt

Location

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: OTHER
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor

Study Record Dates

• First Submitted: March 8, 2026
• First Posted: March 12, 2026
• Study Start: March 15, 2026
• Primary Completion: July 15, 2026
• Study Completion: July 16, 2026
• Last Updated: July 20, 2026

Record last verified: 2026-07

Data Sharing

• IPD Sharing: Will not share

Locations

EG (1)