NCT07465419

Brief Summary

The aim of this study is to evaluate the effect of internal jugular vein catheterization on intracranial pressure in intubated patients in the intensive care unit using optic nerve sheath diameter

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
50

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Feb 2026

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 1, 2026

Completed
1 month until next milestone

First Submitted

Initial submission to the registry

March 7, 2026

Completed
4 days until next milestone

First Posted

Study publicly available on registry

March 11, 2026

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 28, 2026

Completed
4 days until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2026

Completed
Last Updated

June 22, 2026

Status Verified

June 1, 2026

Enrollment Period

4 months

First QC Date

March 7, 2026

Last Update Submit

June 17, 2026

Conditions

Intracranial Pressure MeasurementMeasurement of Optic Nerve Sheath Diameter

Outcome Measures

Primary Outcomes (1)

  • Optic nerve sheath diameter

    Optic nerve sheath diameter will be measured via ultrasound prior to IJV catheterization, and after 0, 5, 15, 30 minutes of catheterization

    Prior to IJV catheterization, and after 0, 5, 15, 30 minutes of catheterization

Study Arms (1)

IJV catheterization in ICU

Intubated patients in intensive care unit who receive internal jugular vein catheterization

Procedure: Internal jugular vein catheterization

Interventions

Internal jugular vein catheterizationPROCEDURE

Internal jugular vein catheterization

IJV catheterization in ICU

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Intubated intensive care unit patients who receive internal jugular vein catheterization

You may qualify if:

  • The study will include adult patients over 18 years of age who are on mechanical ventilation support and monitored in the intensive care unit.

You may not qualify if:

  • patients with intracranial tumors
  • patients with acute traumatic brain injury
  • patients diagnosed with acute or chronic eye diseases
  • hypercarbic patients
  • Patients receiving inotropic support
  • patients using medications that affect intraocular pressure

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Sivas Cumhuriyet University

Sivas, Sivas, 58140, Turkey (Türkiye)

Location

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Associate Professor

Study Record Dates

First Submitted

March 7, 2026

First Posted

March 11, 2026

Study Start

February 1, 2026

Primary Completion

May 28, 2026

Study Completion

June 1, 2026

Last Updated

June 22, 2026

Record last verified: 2026-06

Data Sharing

IPD Sharing
Will not share

Locations

TU(1)