Central Sensitization and Clinical Parameters in Chronic Neck Pain

NCT07462416 | Completed DMC

• 1 other identifier: TurkogluBeyazitSH
• Study Type: observational
• Target: 84
• Locations: 1 country
• Sites: 1

Brief Summary

This study is a retrospective, cross-sectional observational study that assesses the correlations among central sensitization, pain, psychosocial factors, and temporomandibular function in patients with chronic neck pain. It underscores the importance of the biopsychosocial model in clinical practice and aims to improve understanding of central mechanisms in treatment planning. treatment planning.

Conditions

Neck Pain; Central Nervous System Sensitization; Temporomandibular Joint Dysfunction Syndrome; Chronic Pain

Keywords

Neck Pain; Central Sensitization; Catastrophization; Disability

Outcome Measures

Primary Outcomes (2)

• Central Sensitization Inventory (CSI)

  Central sensitization was assessed using the CSI, a tool applicable in cases of chronic pain. The CSI has two parts. Part A evaluates symptoms and is scored from 0 to 100; higher scores reflect greater central sensitization. A score of 30 or higher suggests the presence of central sensitization. Part B asks if the individual has ever been diagnosed with any central sensitization syndromes.

  At baseline (single time-point assessment)

• Visual Analog Scale (VAS)

  Pain intensity will be assessed using the Visual Analog Scale (VAS). The VAS is commonly employed in clinical practice because it is simple to use and consistent. The scale ranges from 0 to 10, where "0" indicates no pain and "10" signifies the worst possible pain. Patients are informed that pain severity increases from 0 to 10 and are asked to mark the number that best reflects their pain level.

  At baseline

Secondary Outcomes (5)

• Pain Catastrophizing Scale (PCS)

  At baseline (single time-point assessment)

• Neck Disability Index

  At baseline (single time-point assessment)

• Pittsburgh Sleep Quality Index (PSQI)

  At baseline (single time-point assessment)

• Jaw Functional Limitation Scale-20 (JFLS-20)

  At baseline

• Assessment of Pressure Pain Threshold

  At baseline

Eligibility Criteria

• Age: 18 Years - 60 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

The study population includes patients living in Kahramanmaraş who have chronic neck pain. The sample consists of these patients who visited our clinic with this issue, received a diagnosis of chronic neck pain from a specialist, and agreed to take part in the study.

You may qualify if:

• \- Patients aged 18-60 years
• Patients with neck pain lasting at least 3 months.
• Patients with a pain intensity of 4 or higher on the Visual Analog Scale (VAS).
• Patients with a Pain Catastrophizing Scale (PCS) score greater than 30.
• Patients with a Central Sensitization Inventory (CSI) score greater than 30.
• Patients who have not received physiotherapy or manual therapy in the past 3 months.

You may not qualify if:

• \- Individuals with a history of neck or spinal surgery.
• Patients with a history of whiplash injury or fracture.
• Individuals with unstable neurological findings.
• Presence of cervical pathology such as herniation or nerve root compression.
• Regular use of analgesic or anti-inflammatory medications.

Sponsors & Collaborators

• Turkoglu Dr. Kemal Beyazit State Hospital: lead

Study Sites (1)

Türkoğlu Dr. Kemal Beyazıt State Hospital

Kahramanmaraş, 46000, Turkey (Türkiye)

Location

Related Publications (1)

• No publications yet

  BACKGROUND

Related Links

• The hospital where the study was conducted

MeSH Terms

Conditions

Neck Pain; Temporomandibular Joint Dysfunction Syndrome; Chronic Pain

Condition Hierarchy (Ancestors)

Pain; Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Temporomandibular Joint Disorders; Craniomandibular Disorders; Mandibular Diseases; Jaw Diseases; Musculoskeletal Diseases; Joint Diseases; Muscular Diseases; Myofascial Pain Syndromes; Stomatognathic Diseases

Study Officials

• Aysenur TUNCER, PT,PhD

  Independent researcher

  STUDY DIRECTOR

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: PT, Phd

Study Record Dates

• First Submitted: March 4, 2026
• First Posted: March 10, 2026
• Study Start: April 5, 2024
• Primary Completion: December 17, 2024
• Study Completion: January 18, 2025
• Last Updated: March 10, 2026

Record last verified: 2026-03

Data Sharing

• IPD Sharing: Will share
• Shared Documents: SAP
• Time Frame: Start Date: 2026-06-01 End Date: 2031-06-01
• Access Criteria: Data will be shared with researchers who submit a reasonable request describing the planned analyses and agree to use the data for research purposes only. A data use agreement may be required.

Locations

TU (1)