NCT07458776

Brief Summary

This randomized clinical trial aimed to compare the effects of Muscle Energy Techniques (METs) and Pilates exercises on pain and physical function in individuals with nonspecific low back pain. A total of 72 participants aged between 20 and 50 years were recruited from the University of Lahore Teaching Hospital, Lahore. Participants were randomly allocated into two groups: one group received Muscle Energy Techniques and the other group performed Pilates exercises. Each intervention session lasted 60 minutes, conducted four days per week for six weeks. Pain intensity was assessed using the Numeric Pain Rating Scale (NPRS), while physical function was evaluated using the Roland Morris Disability Questionnaire (RMDQ). The results were analyzed to determine the comparative effectiveness of the two interventions in reducing pain and improving functional ability among patients with nonspecific low back pain.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
72

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Jun 2025

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 30, 2025

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 25, 2025

Completed
17 days until next milestone

Study Completion

Last participant's last visit for all outcomes

October 12, 2025

Completed
5 months until next milestone

First Submitted

Initial submission to the registry

March 4, 2026

Completed
5 days until next milestone

First Posted

Study publicly available on registry

March 9, 2026

Completed
Last Updated

March 9, 2026

Status Verified

March 1, 2026

Enrollment Period

3 months

First QC Date

March 4, 2026

Last Update Submit

March 4, 2026

Conditions

Keywords

Low Back PainPilates ExercisesPhysical TherapyRehabilitationPain Management

Outcome Measures

Primary Outcomes (1)

  • Pain Intensity

    Pain intensity was assessed using the Numeric Pain Rating Scale (NPRS), an 11-point scale ranging from 0 (no pain) to 10 (worst imaginable pain).

    Baseline and after 6 weeks of intervention

Secondary Outcomes (1)

  • Physical Function

    Baseline and after 6 weeks of intervention

Study Arms (2)

Muscle Energy Technique Group

EXPERIMENTAL

Participants in this group received Muscle Energy Techniques including post-isometric relaxation and reciprocal inhibition techniques targeting the iliopsoas, quadratus lumborum, and erector spinae muscles. Each treatment session lasted 60 minutes and was conducted four times per week for six weeks.

Other: Muscle Energy Technique

Pilates Exercise Group

ACTIVE COMPARATOR

Participants in this group performed a structured Pilates exercise program including core strengthening, flexibility exercises, and postural control activities for 60 minutes per session, four times per week for six weeks.

Behavioral: Pilates Exercises

Interventions

Muscle Energy Technique is a manual therapy intervention where the patient performs voluntary muscle contractions against therapist resistance followed by stretching to improve muscle flexibility, reduce pain, and enhance joint mobility.

Muscle Energy Technique Group

Pilates exercises are structured physical exercises focusing on core muscle strengthening, flexibility, posture improvement, and body awareness to enhance functional movement and reduce musculoskeletal pain.

Pilates Exercise Group

Eligibility Criteria

Age20 Years - 50 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Individuals aged 20-50 years
  • Both males and females
  • Pain lasting for at least 2-3 months
  • Pain score greater than 3 on Numeric Pain Rating Scale
  • Participants who had not received physiotherapy treatment for low back pain

You may not qualify if:

  • History of lumbar radiculopathy
  • Use of painkiller medications
  • Spinal pathologies such as prolapsed disc, spinal stenosis, spondylolisthesis, vertebral fractures, or spinal infections
  • Systemic diseases such as rheumatoid arthritis, ankylosing spondylitis, fibromyalgia, or malignancy
  • Pregnant women
  • Neurological conditions such as stroke or multiple sclerosis
  • Heart conditions or psychological disorders

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Lahore

Lahore, Pakistan

Location

Related Publications (25)

  • Lytras, D., Iakovidis, P., Sykaras, E., Kottaras, A., Kasimis, K., Myrogiannis, I., Barouxakis, A., & Tarfali, G. (2023). Effects of a tailored mat-Pilates exercise program for older adults on pain, functioning, and balance in women with chronic non-specific low back pain: a randomized controlled trial. Aging clinical and experimental research, 35(12), 3059-3071.

    BACKGROUND
  • Li, W., Gong, Y., Liu, J., Guo, Y., Tang, H., Qin, S., Zhao, Y., Wang, S., Xu, Z., & Chen, B. (2021). Peripheral and central pathological mechanisms of chronic low back pain: a narrative review. Journal of pain research, 1483-1494.

    BACKGROUND
  • Kripa, S., & Kaur, H. (2021). Identifying relations between posture and pain in lower back pain patients: a narrative review. Bulletin of Faculty of Physical Therapy, 26, 1-4.

    BACKGROUND
  • Kersten, R., Fikkers, J., Wolterbeek, N., Öner, F., & Van Gaalen, S. (2021). Are the Roland Morris Physical function Questionnaire and Oswestry Physical function Index interchangeable in patients after lumbar spinal fusion? Journal of Back and Musculoskeletal Rehabilitation, 34(4), 605-611.

    BACKGROUND
  • Kant, S., Urvashi, K. J., & Raman, R. K. (2024). Effectiveness of Core Stabilization Exercises vs. Traditional Physical Therapy for Chronic Low Back Pain. Journal of Contemporary Clinical Practice, 10, 279-287.

    BACKGROUND
  • Jenks, A., Hoekstra, T., van Tulder, M., Ostelo, R. W., Rubinstein, S. M., & Chiarotto, A. (2022). Roland-Morris physical function questionnaire, Oswestry physical function index, and Quebec back pain physical function scale: which has superior measurement properties in older adults with low back pain? Journal of Orthopaedic & Sports Physical Therapy, 52(7), 457-469.

    BACKGROUND
  • Hayden, J. A., Ellis, J., Ogilvie, R., Malmivaara, A., & van Tulder, M. W. (2021). Exercise therapy for chronic low back pain. Cochrane Database of Systematic Reviews(9).

    BACKGROUND
  • Goudman, L., Pilitsis, J., Billet, B., De Vos, R., Hanssens, K., Billot, M., Roulaud, M., Rigoard, P., & Moens, M. (2024). The level of agreement between the numerical rating scale and visual analogue scale for assessing pain intensity in adults with chronic pain. Anaesthesia, 79(2), 128-138.

    BACKGROUND
  • Frota, N. T., Fidelis-de-Paula-Gomes, C. A., Pontes-Silva, A., Pinheiro, J. S., de Jesus, S. F. C., Apahaza, G. H. S., da Silva Souza, C., Avila, M. A., & Dibai-Filho, A. V. (2022). 15-item Roland-Morris Physical function Questionnaire (RMDQ-15): structural and criterion validity on patients with chronic low back pain. BMC musculoskeletal disorders, 23(1), 978.

    BACKGROUND
  • Franks, J., Thwaites, C., & Morris, M. E. (2023). Pilates to improve core muscle activation in chronic low back pain: a systematic review. Healthcare,

    BACKGROUND
  • Erawan, T., Sudaryanto, S., & Nur, M. a. (2021). Effectiveness Combination Muscle Energy Technique and Strain Counterstrain Lumbar and Functional Changes to The Range of Motion in Patients With Non Specific Low Back Pain. Urban Health, 3(1), 1-10.

    BACKGROUND
  • Elahi, A. R., Seidi, F., & Karimi zadeh Ardakani, M. (2021). Effect of 8 Weeks of Selected Corrective Exercises on the Lumbar Lordosis Angle and LowerLimb Function in Non-Athlete Men with Lumbar Hyper Lordosis. Journal of Safety Promotion and Injury Prevention, 9(4), 304-314.

    BACKGROUND
  • El Gendy, M. H., Hekal, H. N., Kadah, M. A., Hussein, H. M., & Ewais, N. F. (2022). Pilate mat exercise versus muscle energy technique on chronic non specific low back pain. International Journal of Health Sciences, 6(S5), 3570-3583.

    BACKGROUND
  • Du, S., Liu, W., Cai, S., Hu, Y., & Dong, J. (2020). The efficacy of e-health in the self-management of chronic low back pain: a meta analysis. International journal of nursing studies, 106, 103507.

    BACKGROUND
  • Childress, M. A., & Stuek, S. J. (2020). Neck pain: initial evaluation and management. American family physician, 102(3), 150-156.

    BACKGROUND
  • Chiarotto, A., & Koes, B. W. (2022). Nonspecific low back pain. New England Journal of Medicine, 386(18), 1732-1740.

    BACKGROUND
  • Chauhan, P., Khare, K., Vachchani, K., & Kapoor, G. (2022). Effectiveness of muscle energy technique versus positional release therapy on range of motion and pain in non-specific low back pain. Indian Journal of Continuing Nursing Education, 23(1), 54-58.

    BACKGROUND
  • Bogduk, N. (2022). Clinical and Radiological Anatomy of the Lumbar Spine: Clinical and Radiological Anatomy of the Lumbar Spine-E-Book. Elsevier Health Sciences.

    BACKGROUND
  • Bhosale, S. V., & Burungale, M. (2022). Effectiveness of myofascial release, muscle energy technique and stretching of quadrartus lumborum muscle in patients with non-specific low back pain. J Ecophysiol Occup Health, 21, 132-141.

    BACKGROUND
  • Bento, T. P. F., dos Santos Genebra, C. V., Maciel, N. M., Cornelio, G. P., Simeão, S. F. A. P., & de Vitta, A. (2020). Low back pain and some associated factors: is there any difference between genders? Brazilian journal of physical therapy, 24(1), 79-87.

    BACKGROUND
  • Batıbay, S., Külcü, D. G., Kaleoğlu, Ö., & Mesci, N. (2021). Effect of Pilates mat exercise and home exercise programs on pain, functional level, and core muscle thickness in women with chronic low back pain. Journal of Orthopaedic Science, 26(6), 979-985.

    BACKGROUND
  • Arul, J., & R, R. (2025). Effect of muscle energy technique versus Pilates on functional outcomes among physiotherapy students with non-specific neck pain. Bulletin of Faculty of Physical Therapy, 30(1), 8.

    BACKGROUND
  • Ali, A., Saleh, M., Abdelaraouf, N., & Elazizi, H. (2022). Effect of core stabilization exercises on lumbar lordotic angle in patients with lumbar disc degeneration. Physiotherapy Quarterly, 30(4), 87-95.

    BACKGROUND
  • Akram, A., Imtiaz, K., Maryem, S., Mahmood, W., Mahmood, T., & Babur, M. N. (2024). Comparison of Pilates exercises versus muscle energy technique with Kinesio taping in non-specific low back pain: a randomized controlled trial. Khyber Medical University Journal, 16(1), 3-9.

    BACKGROUND
  • Ahmed, U. A., Nadasan, T., Van Oosterwijck, J., & Maharaj, S. S. (2021). Effect of dynamic stabilisation exercise therapy enhanced with muscles energy technique on some selected patients outcomes and trunk muscles function in patients with chronic non-specific low back pain: a study protocol. European Journal of Physiotherapy, 23(6), 344-354.

    BACKGROUND

MeSH Terms

Conditions

Low Back PainAgnosia

Interventions

Exercise Movement Techniques

Condition Hierarchy (Ancestors)

Back PainPainNeurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and SymptomsPerceptual DisordersNeurobehavioral ManifestationsNervous System Diseases

Intervention Hierarchy (Ancestors)

Physical Therapy ModalitiesTherapeutics

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Masking Details
Participants were not informed about the comparative purpose of the interventions to minimize bias.
Purpose
TREATMENT
Intervention Model
PARALLEL
Model Details: Two groups were formed. Participants were randomly assigned to receive either Muscle Energy Techniques or Pilates exercises for six weeks, and outcomes were compared between groups.
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Doctor of Physical Therapy Student

Study Record Dates

First Submitted

March 4, 2026

First Posted

March 9, 2026

Study Start

June 30, 2025

Primary Completion

September 25, 2025

Study Completion

October 12, 2025

Last Updated

March 9, 2026

Record last verified: 2026-03

Data Sharing

IPD Sharing
Will not share

Individual participant data will not be shared because this study was conducted as an academic research project. The informed consent obtained from participants did not include provisions for public data sharing, and the dataset contains sensitive personal health information. Data will be stored securely and used only for academic and research purposes in accordance with institutional ethics approval

Locations