The Effect of Water With Anti-Inflammatory Capabilities on the Inflammatory Response to Heavy Resistance Exercise

NCT07456683 | Completed

• 1 other identifier: 2102314312
• Study Type: interventional
• Target: 40
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this research is to assess the anti-inflammatory effects of berry-flavored water in response to an acute bout of exercise. This investigation is part of a larger collaborative project between the Exercise Science Research Center, the Center for Human Nutrition, and the University of Arkansas Sensory Science Center, which seeks to examine the potential of waters infused with naturally occurring bioactive anti-inflammatory volatile compounds to improve overall health. We expect that this water infused with natural bioactive berry volatile compounds will demonstrate preventive physiological benefits in relation to systemic inflammation, including a decreased level of baseline (resting) inflammation and attenuated post-exercise inflammation.

Conditions

Systemic Inflammation; Hydration; Resting Metabolism

Outcome Measures

Primary Outcomes (1)

• Inflammation

  Innflammatory biomarkers

  Baseline, Post-lifting, day 1 post, day 2 post, 3-week post, baseline 2, post-lifting 2, day1 (2), day 2 (2). All over a 6-wk period

Study Arms (1)

Consuming WAC beverage for 6 weeks

EXPERIMENTAL

Other: We made a water with berry essence volatiles (cranberry, blackberry, and blueberry). This was consumed for 6 weeks.

Interventions

We made a water with berry essence volatiles (cranberry, blackberry, and blueberry). This was consumed for 6 weeks. OTHER

Participants consumed 1L of special water every day for 6 weeks.

Consuming WAC beverage for 6 weeks

Eligibility Criteria

• Age: 18 Years - 39 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Sedentary to moderately active, as defined by the International Physical Activity Questionnaire (IPAQ)

You may not qualify if:

• Kidney, liver, cardiac, or immune conditions that may compromise their health Not used to lifting weights more than 1 time per month. Participants identified as being 'high fruit/vegetable consumers' will also be excluded from the study because they habitually consume polyphenols and antioxidants already exhibiting anti-inflammatory effects that would compromise our findings.
• A history of fainting from routine blood draws.

Sponsors & Collaborators

• University of Arkansas, Fayetteville: lead

Study Sites (1)

University of Arkansas Exercise Science Research Center

Fayetteville, Arkansas, 72701, United States

Location

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor

Study Record Dates

• First Submitted: March 2, 2026
• First Posted: March 6, 2026
• Study Start: May 17, 2021
• Primary Completion: February 10, 2024
• Study Completion: February 10, 2024
• Last Updated: March 6, 2026

Record last verified: 2026-03

Locations

US (1)