Humidity Asthma Interventions for Low Socioeconomic Status Children

NCT07453667 | Recruiting

• 2 other identifiers: STUDY20231336FR-6700-N-15
• Study Type: interventional
• Target: 80
• Locations: 1 country
• Sites: 2

Brief Summary

The goal of this intervention study is to assess the effectiveness of low-cost humidity and mold reduction interventions in the home for reducing pediatric asthma. The study will have two groups, a treatment group that receives the healthy home interventions during the study and a second control group that will receive these after the study. We will compare pediatric asthma before and three months after the healthy home interventions are performed.

Conditions

Pediatric Asthma

Keywords

asthma; environmental health; indoor air quality; endotoxin; mold; humidity

Outcome Measures

Primary Outcomes (4)

• Change in pediatric asthma control

  Pediatric asthma control is assessed using the Asthma Control Questionnaire (ACQ), a six-item survey consisting of questions specific to asthma symptoms and bronchodilator usage. Questions are answered using a 7-point Likert scale and scored cumulatively with lower scores indicating greater asthma control. Lower scores at 3 months compared to baseline indicate overall improvement in asthma control post-intervention.

  Baseline and 3 months

• Change in asthma-related quality of life

  Asthma-related quality of life is assessed using the Pediatric Asthma Caregiver's Quality of Life Questionnaire (PACQLQ), a thirteen-item survey to assess problems that caregivers experience as a result of their child's asthma. Questions are answered using a 7-point Likert scale and scored cumulatively with higher scores indicating less impact on quality of life. Higher scores at 3 months compared to baseline indicate overall improvement in quality of life.

  Baseline and 3 months

• Hospitalizations

  Change in frequency of hospitalizations/emergency room utilization

  Baseline and 3 months

• Missing work/school

  Change in the number of self-reported missed work or school days

  Baseline and 3 months

Study Arms (2)

Control

NO INTERVENTION

No humidity interventions implemented

Intervention

EXPERIMENTAL

Received the humidity interventions

Other: Healthy home intervention

Interventions

Healthy home intervention OTHER

Healthy home interventions including low cost humidity interventions.

Intervention

Eligibility Criteria

• Age: Up to 18 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64)

You may qualify if:

• Documented diagnosis of asthma by one child (\< 18 years of age) living within the home
• Parent/guardian able to complete informed consent
• Residence within the City of Cleveland or immediate suburbs (e.g., East Cleveland, Garfield Heights, Warrensville Heights, Parma, Brook Park, Brooklyn/Old Brooklyn)

You may not qualify if:

• \> 18 years of age
• Rental property with landlord unwilling or unable to give consent for remediation

Sponsors & Collaborators

• Case Western Reserve University: lead
• The Cleveland Clinic: collaborator

Study Sites (2)

Case Western Reserve University

Cleveland, Ohio, 44106, United States

RECRUITING

Cleveland Clinic

Cleveland, Ohio, 44195, United States

NOT YET RECRUITING

MeSH Terms

Conditions

Asthma

Condition Hierarchy (Ancestors)

Bronchial Diseases; Respiratory Tract Diseases; Lung Diseases, Obstructive; Lung Diseases; Respiratory Hypersensitivity; Hypersensitivity, Immediate; Hypersensitivity; Immune System Diseases

Study Officials

• Bridget Hegarty, PhD

  Case Western Reserve University

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Bridget Hegarty, PhD

CONTACT

216-368-2950; beh53@case.edu

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: PREVENTION
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: March 2, 2026
• First Posted: March 6, 2026
• Study Start: May 2, 2026
• Primary Completion (Estimated): December 31, 2026
• Study Completion (Estimated): May 1, 2027
• Last Updated: June 3, 2026

Record last verified: 2026-06

Data Sharing

• IPD Sharing: Will not share

Locations

US (2)