Role of Pro-Resolving Lipid Mediators in Obesity-Associated Diseases
RESOLBE
Unraveling the Role of Pro-Resolving Lipid Mediators of Inflammation and Their Receptors in Obesity-Associated Diseases: New Therapeutic Approaches for Maresin 1 (RESOLBE)
RESOLBE
Unraveling the Role of Pro-Resolving Lipid Mediators of Inflammation and Their Receptors in Obesity-Associated Diseases: New Therapeutic Approaches for Maresin 1 (RESOLBE)
Sponsor study identifier
observational
60
1 country
2
Study Start
October 15, 2025
Actual (reported)Primary Completion
November 30, 2027
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
Study Completion
December 30, 2027
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
The main objective of this project is to determine the possible association between the levels of certain bioactive lipids, which the body produces from dietary fatty acids, and tumor characteristics in breast cancer patients, as well as their relationship with overweight/obesity. Specific objectives are:
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
December 30, 2027
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
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Some registry-reported names shown below are not yet linked in this graph.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
October 15, 2025
Actual (reported)February 25, 2026
Actual (reported)March 3, 2026
Actual (reported)November 30, 2027
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
December 30, 2027
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
Lipid mediators profile
Lipid mediators will be analysed by targeted lipidomic method.
Clinical Investigation Day 1 and Clinical Investigation Day 3
Body weight
Clinical Investigation Day 1 and Clinical Investigation Day 3.
Height
Clinical Investigation Day 1 and Clinical Investigation Day 3.
Body mass index
Clinical Investigation Day 1 and Clinical Investigation Day 3.
Hip circumference
Clinical Investigation Day 1 and Clinical Investigation Day 3.
Waist circumference
Clinical Investigation Day 1 and Clinical Investigation Day 3.
Postmenopausal healthy women with overweight/obesity.
Postmenopausal healthy women with normoweight.
Postmenopausal women with breast cancer and overweight/obesity
Postmenopausal women with breast cancer and normoweight.
Data will be collected at a single time point.
Data will be collected at two time points during the study period.
Postmenopuasal women.
Center for Nutrition Research
Pamplona, Navarre, 31008, Spain
Clínica Universidad de Navarra
Pamplona, Navarre, 31008, Spain
Blood samples. Adipose tissue from breast cancer lumpectomies.
Miguel Burgos, PhD
Center for Nutrition Research
María Jesús Moreno-Aliaga, PhD
Center for Nutrition Research
María Soledad García-Unciti, PhD
Center for Nutrition Research
Idoia Ibero-Baraibar, PhD
Center for Nutrition Research
First Submitted
February 25, 2026
First Posted
March 3, 2026
Study Start
October 15, 2025
Actual (reported)Primary Completion
November 30, 2027
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.
Contact the study team to confirm eligibility.
Iosune Zubieta
Center for Nutrition Research
Salomé Pérez
Center for Nutrition Research
Asunción Redín
Center for Nutrition Research
Andrea Lara
Center for Nutrition Research
María Pilar Lostao, PhD
Center for Nutrition Research
Natalia Rodríguez-Spiteri, PhD
Clinica Universidad de Navarra, Universidad de Navarra
Begoña Olartecoechea, PhD
Clinica Universidad de Navarra, Universidad de Navarra
Ángel Vizcay, PhD
Clinica Universidad de Navarra, Universidad de Navarra
Marta Santisteban, PhD
Clinica Universidad de Navarra, Universidad de Navarra
Study Completion
December 30, 2027
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
Last Updated
March 11, 2026
Record last verified: 2026-03
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Source: ClinicalTrials.gov.
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