Sensory Analysis and Cutaneous Mapping of Different Regional Anesthesia Techniques

NCT07445854 | Recruiting

• 1 other identifier: GOKAEK 2025/20/13
• Study Type: observational
• Target: 40
• Locations: 1 country
• Sites: 1

Brief Summary

This prospective observational study aims to evaluate and compare the sensory block distribution and regression patterns of two regional anesthesia techniques - External Oblique Plane Block (EOPB) and Serratus Intercostal Plane Block (SIPB) - in patients undergoing laparoscopic cholecystectomy. Thirty adult patients (ASA I-III, BMI ≤ 35 kg/m², ≥50 kg) scheduled for elective laparoscopic cholecystectomy procedures will be included, with 20 in each block group. Sensory block areas will be assessed using pinprick test, and dermatomal mapping will visualize the spread. The findings are expected to improve understanding of block behavior and guide multimodal analgesia strategies in laparoscopic cholecystectomy.

Conditions

Laparoscopic Cholecystectomy; Postoperative Pain Management; Regional Anesthesia

Keywords

regional anesthesia; Pain Management; Sensory Mapping; serratus intercostal plane block; external oblique plane block; eopb; sipb

Outcome Measures

Primary Outcomes (1)

• Cutaneous Sensory Block Area of EOPB and SIPB

  The primary outcome is the dermatomal mapping of the cutaneous sensory block areas produced by the serratus intercostal plane block (SIPB) and external oblique plane block (EOPB), and the comparison of sensory block extent between the two techniques.

  30 minutes after block application

Secondary Outcomes (3)

• Coverage of Surgical Port Entry Sites by the Sensory Block Area

  30 minutes after block application

• Maximum and Minimum Spread of the Cutaneous Sensory Block Area

  30 minutes after block application

• Block Application Duration

  From needle insertion to completion of local anesthetic injection

Study Arms (2)

EOPB Group

Patients undergoing laparoscopic cholecystectomy who receive an ultrasound-guided External Oblique Plane Block (EOPB) for postoperative analgesia. Bilateral blocks will be performed using 0.25% bupivacaine (25 mL per side, total 50 mL). Sensory block areas will be evaluated using pinprick at predefined time points.

Procedure: External Oblique Plane Block (EOPB)

SIPB Group

Patients undergoing laparoscopic cholecystectomy who receive an ultrasound-guided Serratus Intercostal Plane Block (SIPB) for postoperative analgesia. Bilateral blocks will be performed using 0.25% bupivacaine (25 mL per side, total 50 mL). Sensory block areas will be evaluated using pinprick at predefined time points.

Procedure: Serratus Intercostal Plane Block (SIPB)

Interventions

External Oblique Plane Block (EOPB) PROCEDURE

Ultrasound-guided External Oblique Plane Block (EOPB) performed bilaterally using 0.25% bupivacaine (25 mL per side, total 50 mL) for postoperative analgesia in laparoscopic cholecystectomy.

EOPB Group

Serratus Intercostal Plane Block (SIPB) PROCEDURE

Ultrasound-guided Serratus Intercostal Plane Block (SIPB) performed bilaterally using 0.25% bupivacaine (25 mL per side, total 50 mL) for postoperative analgesia in laparoscopic cholecystectomy.

SIPB Group

Eligibility Criteria

• Age: 18 Years - 75 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients who are scheduled to undergo elective laparoscopic cholecystectomy surgery under general anesthesia at the Department of Anesthesiology, Samsun University Training and Research Hospital. A total of 40 patients will be enrolled and divided into two groups: EOPB (n=20) and SIPB (n=20). Each participant will receive ultrasound-guided regional anesthesia according to their assigned group, and sensory mapping will be performed postoperatively.

You may qualify if:

• Patients scheduled for elective laparoscopic cholecystectomy surgery and who have received a regional anesthesia technique for this purpose.
• Aged between 18-75 years.
• Belonging to ASA I-III group.
• Having provided written informed consent.

You may not qualify if:

• Patients who refuse to participate.
• Patients who did not receive a block.
• Patients classified as ASA IV.
• History of previous abdominal surgery (affecting the laparoscopic approach).
• Patients with cognitive dysfunction or inability to cooperate.
• Patients diagnosed with psychiatric disorders (schizophrenia, mania, depression, etc.).
• Patients who have been using antipsychotic medication for more than 4 weeks.

Sponsors & Collaborators

• Samsun University: lead

Study Sites (1)

Samsun University, Samsun Training and Research Hospital

Samsun, Ilkadım, 55200, Turkey (Türkiye)

RECRUITING

Related Publications (3)

• Nielsen TD, Moriggl B, Barckman J, Kolsen-Petersen JA, Soballe K, Borglum J, Bendtsen TF. The Lateral Femoral Cutaneous Nerve: Description of the Sensory Territory and a Novel Ultrasound-Guided Nerve Block Technique. Reg Anesth Pain Med. 2018 May;43(4):357-366. doi: 10.1097/AAP.0000000000000737.

  PMID: 29381568 BACKGROUND

• Dost B, Turunc E, Kaya C, Sahin CA, Genc C, Yucel SM, Demirag MK, Karakaya D. Maximum extension and regression rate of cutaneous sensory block: superficial vs. deep parasternal intercostal plane blocks in patients undergoing open cardiac surgery. J Clin Anesth. 2025 Jul;105:111888. doi: 10.1016/j.jclinane.2025.111888. Epub 2025 May 30.

  PMID: 40449315 BACKGROUND

• Genc C, Tulgar S, Akgun C, Avci MA, Yesilyurt B, Yildiz B, DE Cassai A. Maximum extension and regression rate of cutaneous sensory block obtained with the external oblique intercostal block or the modified thoracoabdominal nerves block through perichondrial approach in patients undergoing laparoscopic cholecystectomy. Minerva Anestesiol. 2024 Nov;90(11):979-988. doi: 10.23736/S0375-9393.24.18213-2.

  PMID: 39545654 BACKGROUND

MeSH Terms

Conditions

Agnosia

Condition Hierarchy (Ancestors)

Perceptual Disorders; Neurobehavioral Manifestations; Neurologic Manifestations; Nervous System Diseases; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Officials

• Hatice Selcuk Kusderci, M.D.

  Samsun University Training and Research Hospital

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Hatice Selcuk Kusderci, M.D.

CONTACT

+905052159896; drkusderci@hotmail.com

Mert Yılmaz, M.D.

CONTACT

+905326699555; dryilmazmert@gmail.com

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: November 21, 2025
• First Posted: March 3, 2026
• Study Start: November 15, 2025
• Primary Completion (Estimated): May 15, 2026
• Study Completion (Estimated): June 1, 2026
• Last Updated: March 3, 2026

Record last verified: 2026-02

Locations

TU (1)