Evidence-based Intervention for Diabetes Prevention

NCT07443995 | Not Yet Recruiting

• 1 other identifier: ADHRTC-2025-195/HRPP-2023-238
• Study Type: interventional
• Target: 30
• Locations: 1 country
• Sites: 1

Brief Summary

The goal of this behavioral intervention trial is to develop strategies to decrease the incidence of diabetes within the UAE. The investigators will investigate the effectiveness of a group-based telehealth intervention facilitated by a health coach in adults at risk for developing diabetes who live in the UAE. The investigators will conduct a single-arm feasibility trial of the Evidence-based Intervention for Diabetes prevention among thirty adults with prediabetes. All participants will receive 12 weekly virtual intervention sessions over the course of three months, facilitated by a trained DPP lifestyle coach who is from the same cultural community and can deliver the material in either Arabic or English. The primary feasibility measure is acceptability, as measured by intervention session attendance. Other outcome assessments will be conducted at baseline and three months at NYU Abu Dhabi, where study staff will assess weight, hemoglobin A1c, diet, and physical activity.

Conditions

Pre-diabetes; Lifestyle Risk Reduction; Diet Prevention of Metabolic Diseases

Keywords

pre-diabetes; behavioral intervention; diet; physical activity

Outcome Measures

Primary Outcomes (1)

• Intervention acceptability based on the proportion of sessions attended

  Acceptability of the intervention will be measured by the number (%) of intervention sessions attended. Each participant will be offered 12 intervention sessions, and the acceptability of the intervention will be measured by the proportion of sessions attended (# sessions attended/ 12).

  3 months (post intervention)

Secondary Outcomes (1)

• Changes in glycemia

  0 and 3 months

Other Outcomes (1)

• Weight loss

  0 and 3 months

Study Arms (1)

Group facilitated behavioral counseling arm

EXPERIMENTAL

Participants in this arm will participate in 12 group counseling sessions online. Sessions will be weekly. The 12 sessions are adapted from the CDC DPP program and will deliver culturally appropriate information on diet and activity to prevent diabetes. The participants will have access to video content and will also receive written curricular materials. All materials are culturally adapted and translated into Arabic. The participants will also have access to a local smartphone app to assist with goal setting, logging physical activity and food intake, as well as receiving additional personalized health recommendations.

Behavioral: Adapted diabetes prevention program; Behavioral: App based support; Behavioral: Patient education materials

Interventions

Adapted diabetes prevention program BEHAVIORAL

The intervention is based on the CDC Diabetes Prevention Program and has been adapted into a culturally appropriate intervention in an Arab context. The program has been condensed into 12 sessions with an additional session that addresses lifestyle factors during Ramadan. Each session covers a different topic related to diet, physical activity, sleep, and stress management. Additionally, the intervention includes written materials to help participants develop lifestyle goals and encourages them to seek social support. There are a series of 12 videos in Arabic and English that support the information delivered in the group sessions. In addition to the group sessions, participants will have access to the automated app and education materials.

Group facilitated behavioral counseling arm

App based support BEHAVIORAL

This intervention will provide educational videos that have been culturally adapted to the Arab context and additional automated supports for lifestyle modification. Study participants will be provided with access to an app that they will be encouraged to engage with on a regular basis. The app will provide basic diet, physical activity, and lifestyle support to prevent diabetes. Participants will also be able to track activity, diet, and receive feedback on their personal weight, diet habits, and activity levels.

Group facilitated behavioral counseling arm

Patient education materials BEHAVIORAL

Participants will be provided written or web-based diabetes prevention materials. These materials will provide basic tips on diet, physical activity and other lifestyle factors.

Group facilitated behavioral counseling arm

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Men and women 18 years or older
• Diabetes risk score \> 5
• BMI \>=25kg/m\^2
• Arabic or English speaking
• Able to read and write in Arabic or English
• Access to a smartphone
• Provide informed consent

You may not qualify if:

• Prevalent diabetes
• Prior participation in a diabetes prevention program
• Taking FDA-approved weight loss medications
• Pregnant or lactating

Sponsors & Collaborators

• New York University: lead

Study Sites (1)

New York University Abu Dhabi

Abu Dhabi, 129188, United Arab Emirates

Location

MeSH Terms

Conditions

Glucose Intolerance; Risk Reduction Behavior; Motor Activity

Condition Hierarchy (Ancestors)

Hyperglycemia; Glucose Metabolism Disorders; Metabolic Diseases; Nutritional and Metabolic Diseases; Behavior

Study Officials

• Jeannette Beasley, PhD

  New York University

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Jeannette Beasley, PhD

CONTACT

646-501-4681; jbeasley@nyu.edu

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: PREVENTION
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: January 20, 2026
• First Posted: March 2, 2026
• Study Start: April 1, 2026
• Primary Completion (Estimated): June 1, 2027
• Study Completion (Estimated): August 1, 2027
• Last Updated: March 2, 2026

Record last verified: 2025-10

Data Sharing

• IPD Sharing: Will not share

Locations

AE (1)