Safety and Efficacy in Pain Reduction of CT-Guided Screw Fixation for Post-laminectomy Surgery Segment Spinal Instability: A Monocentric Study of 24 Patients (2023-2026)

NCT07443267 | Completed

• 1 other identifier: 24Radiointerv01
• Study Type: observational
• Target: 24
• Locations: 1 country
• Sites: 1

Brief Summary

Segmental instability of the spine following laminectomy or surgical arthrodesis is a common complication that often requires additional surgical intervention. CT-guided trans-facet screw fixation (TFF), performed under local anesthesia, is an innovative and minimally invasive technique that offers an alternative to open surgery under general anesthesia. This study aims to evaluate the effectiveness of CT-guided TFF fixation in reducing pain and improving daily activities in a population of 24 patients who have undergone prior spinal surgeries

Conditions

Segmental Instability Post-laminectomy

Keywords

Spinal Disease; Adjacent Segment Disease

Outcome Measures

Primary Outcomes (1)

• Change in pain levels between pre-intervention and post-intervention measurements.

  Pain assessed using the Visual Analog Scale (VAS) from 1 to 10,

  Baseline) , 1 month post-intervention, 6 months post-intervention, and 1 year post-intervention.

Secondary Outcomes (1)

• Improvement in quality of life following the intervention.

  Baseline ) 1 month post-intervention 6 months post-intervention and 1 year post-intervention.

Study Arms (1)

Cohorte

Patients diagnosed with segment lumbar instability following spinal surgical procedures such as laminectomy .

Other: No intervention

Interventions

No intervention OTHER

No intervention

Cohorte

Eligibility Criteria

• Age: 41 Years - 93 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients consulting at the University Hospital of Nice (CHU de Nice).

You may qualify if:

• Treated at the University Hospital of Nice between march 2023 and january 2026 with trans-facet arthrodesis for persistent lumbar segment instability following previous laminectomy surgery.
• MRI or scintigraphy imaging showed signs suggestive of instability
• Newly developed or worsening spondylolisthesis on successive examinations
• Congestive arthropathy
• Facet dislocation
• Inflammatory disc disease (MODIC type 1 changes)

You may not qualify if:

• Inability to tolerate the prone position under local anesthesia.
• Presence of anatomical variants precluding the technical feasibility of transfacet fixation.

Sponsors & Collaborators

• Centre Hospitalier Universitaire de Nice: lead

Study Sites (1)

CHU NICE

Nice, Alpes Maritimes, 0600, France

Location

MeSH Terms

Conditions

Spinal Diseases

Condition Hierarchy (Ancestors)

Bone Diseases; Musculoskeletal Diseases

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: February 17, 2026
• First Posted: March 2, 2026
• Study Start: March 8, 2023
• Primary Completion: January 30, 2026
• Study Completion: February 3, 2026
• Last Updated: March 31, 2026

Record last verified: 2026-02

Locations

FR (1)