NCT07441005

Brief Summary

This study is conducted to compare the efficacy of topical oxiconazole 1% cream versus topical clotrimazole 1% cream in patients with tinea cruris.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
386

participants targeted

Target at P75+ for early_phase_1

Timeline
Completed

Started May 2025

Shorter than P25 for early_phase_1

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

May 15, 2025

Completed
5 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 15, 2025

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

October 15, 2025

Completed
4 months until next milestone

First Submitted

Initial submission to the registry

January 29, 2026

Completed
29 days until next milestone

First Posted

Study publicly available on registry

February 27, 2026

Completed
Last Updated

February 27, 2026

Status Verified

February 1, 2026

Enrollment Period

5 months

First QC Date

January 29, 2026

Last Update Submit

February 25, 2026

Conditions

Tinea Cruris

Keywords

Tinea

Outcome Measures

Primary Outcomes (1)

  • Assessment of improvement i

    Assessment of change in pruritis by VAS scoring. Assessment of change in erythema on VAS scoring. .

    Six months

Study Arms (2)

Group A

ACTIVE COMPARATOR

Topical Oxiconazole (1%)

Drug: Topical Oxiconazole cream

Group B

ACTIVE COMPARATOR

Topical Clotrimazole (1%)

Drug: Topical Clotrimazole cream

Interventions

Topical Oxiconazole creamDRUG

Group A will recieve topical Oxiconazole

Group A
Topical Clotrimazole creamDRUG

Group B will recieve topical clotrimazole

Group B

Eligibility Criteria

Age18 Years - 70 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • to 70 years of age
  • Both genders
  • Patient with diagnosis of tinea crurus as per operational definition

You may not qualify if:

  • Hypersensitivity to clotrimazole or Oxiconazole
  • Uncontrolled diabetes
  • Immunosuppresion
  • Patient with contact dermatitis

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Hayatabad medal Complex

Peshawar, KPK, 0000, Pakistan

Location

MeSH Terms

Conditions

Tinea CrurisTinea

Condition Hierarchy (Ancestors)

DermatomycosesMycosesBacterial Infections and MycosesInfectionsSkin Diseases, InfectiousIntertrigoDermatitisSkin DiseasesSkin and Connective Tissue DiseasesSkin Diseases, Eczematous

Study Officials

  • Dr Fahad Khan

    MTI HMC KPK PESHAWAR

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
early phase 1
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER GOV
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Traine Medical Officer

Study Record Dates

First Submitted

January 29, 2026

First Posted

February 27, 2026

Study Start

May 15, 2025

Primary Completion

October 15, 2025

Study Completion

October 15, 2025

Last Updated

February 27, 2026

Record last verified: 2026-02

Locations

PA(1)