NCT07437677

Brief Summary

Home dialysis is encouraged in Canada and peritoneal dialysis is the most common home dialysis method. However, many patients discontinue peritoneal dialysis, often transferring to hemodialysis. Despite the frequency of this transition, little is known about its impact on patients. Overall, the UPLIFT-PD program aims to fill this gap by studying the transition from peritoneal dialysis to hemodialysis. The specific goal of this mixed methods sub-study is to conduct a national survey to ask patients and caregivers about priorities and preferences when they anticipate a transfer from peritoneal dialysis to hemodialysis. This survey will be co-created by patient-partners and dialysis experts. Results from this survey will then be used in other phases of UPLIFT-PD program, detailed in other registrations, which will support people facing a transition from peritoneal dialysis to hemodialysis..

Trial Health

65
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
200

participants targeted

Target at P75+ for all trials

Timeline
36mo left

Started Jan 2027

Typical duration for all trials

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

February 20, 2026

Completed
7 days until next milestone

First Posted

Study publicly available on registry

February 27, 2026

Completed
10 months until next milestone

Study Start

First participant enrolled

January 1, 2027

Expected
11 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2027

2 years until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2029

Last Updated

February 27, 2026

Status Verified

February 1, 2026

Enrollment Period

11 months

First QC Date

February 20, 2026

Last Update Submit

February 24, 2026

Conditions

Keywords

Transfer to hemodialysis

Outcome Measures

Primary Outcomes (1)

  • Priorities and Challenges Related to PD-to-HD Transitions

    Measured using Likert-scale responses assessing perceived importance of transition-related factors (e.g. preparedness, timing of discussions, vascular access planning, psychosocial impact). Likert-scale from 0 (lowest importance) to 9 (highest importance)

    At survey completion (Baseline)

Secondary Outcomes (2)

  • Preferences for Clinical Scenarios Related to PD-to-HD Transitions

    At survey completion (Baseline)

  • Perceptions of Successful Transition

    At survey completion (Baseline)

Other Outcomes (1)

  • Qualitative Themes Related to Transition Experiences

    At survey completion (Baseline)

Study Arms (1)

Survey Participants

Survey participants will include both patients (or their caregivers) having experienced a transition to hemodialysis in the past year or currently receiving peritoneal dialysis

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Adult patients with lived experience of peritoneal dialysis and transitions to hemodialysis, as well as caregivers of such patients, recruited from dialysis centers and patient communities across multiple centers.

You may qualify if:

  • Adult (≥18 years)
  • One of the following:
  • Patient who experienced a PD-to-HD transition in past 12 months
  • Patient currently receiving peritoneal dialysis
  • Caregiver (self-defined, including spouses, family members, or friends) of individuals meeting the above criteria
  • Able to read English or French
  • Able to complete the survey in paper or web-based format
  • Able to provide informed consent

You may not qualify if:

  • Age \<18 years
  • Unable to provide consent

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Officials

  • Annie-Claire Nadeau-Fredette, MD MSc

    CIUSSS de l'Est-de-l'Ile de Montréal

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Annie-Claire Nadeau-Fredette, MD MSc

CONTACT

Study Design

Study Type
observational
Observational Model
OTHER
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Nephrologist, Clinical Scientist

Study Record Dates

First Submitted

February 20, 2026

First Posted

February 27, 2026

Study Start (Estimated)

January 1, 2027

Primary Completion (Estimated)

December 1, 2027

Study Completion (Estimated)

December 1, 2029

Last Updated

February 27, 2026

Record last verified: 2026-02

Data Sharing

IPD Sharing
Will not share

Considering the survey nature of the study and in compliance with our ethic board requirements