Knee Pain and Lumbar Proprioception in Knee Osteoarthritis Patients

NCT07436897 | Completed DMC

• 1 other identifier: Physical Therapy 25055
• Study Type: observational
• Target: 56
• Locations: 1 country
• Sites: 1

Brief Summary

Knee osteoarthritis (KOA), is a chronic degenerative joint pathology with a global prevalence of 22.9% in individuals aged 40 and over. It is a leading cause of disability and poor quality of life worldwide due to musculoskeletal pain and functional limitations. Musculoskeletal pain is the primary patient-reported outcome in patients with osteoarthritis (OA) and a major cause of disability and functional limitations this study was carried to investigate the correlation between knee pain and lumbar proprioception

Conditions

Osteoarthritis (OA) of the Knee

Keywords

knee pain; Osteoarthritis; Lumbar proprioception; Repositioning error.

Outcome Measures

Primary Outcomes (1)

• proprioception

  Joint position error was measured using the Biodex system 3. Before every test, the system was calibrated and stabilized. The patient was placed in a seated compressed posture on the Biodex system chair. Two curved pads on the front of the legs allowed for individual adjustment of the knee blocks, and the patient's feet were supported in a way that they did not touch the floor, both thighs were stabilized by two straps, the pelvic brace was then applied and positioned as far down as possible to press firmly but comfortably against the superior aspect of the proximal thighs. The starting position for each participant was with their spines flexed at a 60° angle. As a "target position" for the individuals to maintain during the testing, the predetermined spinal ROM was set at 60° to 90° lumbar flexion. All subjects. After recording the subjects' absolute error (AE) values relative to the 90-degree target position for all three trials, the mean deviation was calculated

  at the baseline (day 1)

Secondary Outcomes (1)

• Pain intensity

  at the baseline (day 1)

Study Arms (1)

study group

fifty-six individuals of both sexes between the ages of 40 and 60 years with knee osteoarthritis

Other: porprioception

Interventions

porprioception OTHER

The Biodex system 3 was used to measure joint position error.

study group

Eligibility Criteria

• Age: 40 Years - 60 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)
• Sampling Method: Probability Sample

Study Population

Between the ages of 40 and 60 years, fifty-six individuals of both sexes were recruited, their BMI ranged from 24.02 to 29.98.

You may qualify if:

• Male and female participants diagnosed with knee osteoarthritis.
• The participants diagnosed with grade one, grade two and grade three knee osteoarthritis.
• Subjects aged form 40-60 years old.
• All the participants complain of knee pain.
• Participants able to understand the commands.

You may not qualify if:

• Experienced serious trauma leading to fractures and dislocations of the spine.
• They have been diagnosed to have spinal deformities such as scoliosis, lumbar disc herniation and lumbar spondylolisthesis.
• They have infection/malignant spinal conditions. 4- They have cauda equine syndrome. 5- Anyone with psychological disorders (e.g. dementia or drug abuse). 6- Uncooperative participant 7- Anyone with grade four knee osteoarthritis

Sponsors & Collaborators

• Cairo University: lead

Study Sites (1)

Physical therapy College - Cairo university

Cairo, Egypt

Location

MeSH Terms

Conditions

Osteoarthritis

Condition Hierarchy (Ancestors)

Arthritis; Joint Diseases; Musculoskeletal Diseases; Rheumatic Diseases

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: PROSPECTIVE
• Target Duration: 4 Weeks
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant professor of physical therapy

Study Record Dates

• First Submitted: January 28, 2026
• First Posted: February 27, 2026
• Study Start: May 1, 2025
• Primary Completion: November 1, 2025
• Study Completion: December 20, 2025
• Last Updated: February 27, 2026

Record last verified: 2026-02

Data Sharing

• IPD Sharing: Will not share

Locations

EG (1)