NCT07429981

Brief Summary

The aim of this study is to investigate the effect of nerve gliding exercises on pain, cervical range of motion, joint position sense, grip strength, functional status and quality of life in individuals with cervical radiculopathy.

Trial Health

63
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
28

participants targeted

Target at below P25 for not_applicable

Timeline
1mo left

Started Apr 2026

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress62%
Apr 2026Aug 2026

First Submitted

Initial submission to the registry

February 18, 2026

Completed
6 days until next milestone

First Posted

Study publicly available on registry

February 24, 2026

Completed
1 month until next milestone

Study Start

First participant enrolled

April 1, 2026

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2026

Expected
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2026

Last Updated

February 24, 2026

Status Verified

February 1, 2026

Enrollment Period

3 months

First QC Date

February 18, 2026

Last Update Submit

February 18, 2026

Conditions

Cervical Radiculopathy at C5 Nerve RootCervical Radiculopathy at C6 Nerve RootCervical Radiculopathy at C7 Nerve RootCervical Radiculopathy

Keywords

Cervical radiculopathyNeural glideNeuromobilization

Outcome Measures

Primary Outcomes (1)

  • Visual Analog Scale (VAS)

    The Visual Analog Scale (VAS) will be used to evaluate pain for rest, activity and night periods. The data will be recorded in centimeters.

    3 weeks

Secondary Outcomes (8)

  • Cervical range of motion (CROM)

    3 weeks

  • Nerve cross-sectional area (CSA)

    3 weeks

  • Cervical joint position sense

    3 weeks

  • Nerve excursion measurement

    3 weeks.

  • Deep cervical flexor muscle endurance

    3 weeks

  • +3 more secondary outcomes

Study Arms (2)

Control Group

ACTIVE COMPARATOR

Conventional rehabilitation program (isometric neck strengthening exercises, neck stretching exercises) for cervical radiculopathy.

Other: Convantional rehabilitation

Intervention Group

EXPERIMENTAL

Conventional rehabilitation program (isometric neck strengthening exercises, neck stretching exercises) for cervical radiculopathy and neuromobilization exercises.

Other: Neuromobilization

Interventions

Convantional rehabilitationOTHER

This group will have convantional rehabilitation program.

Control Group
NeuromobilizationOTHER

This group will have convantional rehabilitation program and neuromobilization exercises.

Intervention Group

Eligibility Criteria

Age18 Years - 55 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Have been diagnosed with cervical radiculopathy by a specialist physician
  • Have disc herniation at the C5-C6, C6-C7 or C7-T1 level according to imaging (magnetic resonance imaging, MRI) findings (in the bulging or protrusion stage)
  • Have unilateral nerve root involvement

You may not qualify if:

  • Predominance of primary peripheral entrapment neuropathy (carpal/cubital/radial tunnel, etc.)
  • Multiple nerve root involvement
  • Progressive neurological deficit
  • History of trauma or surgery to the cervical and upper extremity region
  • Systemic disease contraindicating exercise
  • Pregnancy
  • Manual therapy, injection, or regular physiotherapy applied to the cervical region within the last 3 months
  • Cognitive/psychiatric condition preventing compliance with the assessment protocol

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Zonguldak Ataturk State Hospital

Zonguldak, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Radiculopathy

Condition Hierarchy (Ancestors)

Peripheral Nervous System DiseasesNeuromuscular DiseasesNervous System Diseases

Study Officials

  • Eda AKBAŞ

    Zonguldak Bulent Ecevit University

    STUDY CHAIR

  • Öznur GÜNEY

    Zonguldak Bulent Ecevit University

    STUDY CHAIR

  • Merve Demirci, MD

    Zonguldak Ataturk State Hospital

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Eda AKBAŞ, PhD

CONTACT

+903722613341akbas.pt@gmail.com

Öznur GÜNEY, MSc

CONTACT

+903722613342oznur1123@gmail.com

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Masking Details
The researcher who will evaluate the patients before and after treatment will not know which group the patients are in.
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Associate Professor

Study Record Dates

First Submitted

February 18, 2026

First Posted

February 24, 2026

Study Start

April 1, 2026

Primary Completion (Estimated)

July 1, 2026

Study Completion (Estimated)

August 1, 2026

Last Updated

February 24, 2026

Record last verified: 2026-02

Locations

TU(1)