NCT07425496

Brief Summary

The objective of this study is to evaluate ocular outflow dynamics of the eye using intraoperative tonographic biometry and assess its predictive value in improving postoperative outcomes.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
150

participants targeted

Target at P50-P75 for all trials

Timeline
28mo left

Started Aug 2025

Typical duration for all trials

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress29%
Aug 2025Dec 2028

Study Start

First participant enrolled

August 26, 2025

Completed
6 months until next milestone

First Submitted

Initial submission to the registry

February 10, 2026

Completed
13 days until next milestone

First Posted

Study publicly available on registry

February 23, 2026

Completed
1.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2027

Expected
1 year until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2028

Last Updated

February 24, 2026

Status Verified

February 1, 2026

Enrollment Period

2.3 years

First QC Date

February 10, 2026

Last Update Submit

February 20, 2026

Conditions

Keywords

glaucoma surgerycataractglaucoma

Outcome Measures

Primary Outcomes (2)

  • Intraocular Pressure (IOP) measurement calculation during surgery.

    Measure the intra ocular pressure measurement during surgery to better inform surgeons of post-operative management and outcomes.

    90 days

  • Outflow capacity calculation during surgery

    Measure the outflow capacity rate measurement during surgery to better inform surgeons of post-operative management and outcomes.

    90 days

Secondary Outcomes (1)

  • Rate of intraoperative and postoperative complications.

    90 days

Study Arms (2)

Cataract

disposable Deltran I pressure sensor for Cataract

Diagnostic Test: disposable Deltran I pressure sensor

Glaucoma

disposable Deltran I pressure sensor for Glaucoma

Diagnostic Test: disposable Deltran I pressure sensor

Interventions

Intraocular pressure measurements will be taken using an FDA-registered, sterile, single-use, disposable Deltran I pressure sensor designed for measuring physiological pressures of the body.

CataractGlaucoma

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients will be stratified according to disease entity (glaucoma and/or cataract), severity (mild, moderate, etc), and surgery performed (cataract surgery, cataract surgery combined with glaucoma surgery, trabeculectomy, and/or glaucoma device implantation).

You may qualify if:

  • Individuals undergoing cataract and/or glaucoma surgery in the Mount Sinai Health System.

You may not qualify if:

  • Individuals less than 18 years old, pregnant women, those without capacity to make their own decisions, and prisoners.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

New York Eye and Ear Infirmary of Mount Sinai

New York, New York, 10003, United States

RECRUITING

Related Publications (1)

  • Sherwood JM, Reina-Torres E, Bertrand JA, Rowe B, Overby DR. Measurement of Outflow Facility Using iPerfusion. PLoS One. 2016;11(3):e0150694. Published 2016 Mar 7.

    BACKGROUND

MeSH Terms

Conditions

CataractGlaucoma

Condition Hierarchy (Ancestors)

Lens DiseasesEye DiseasesOcular Hypertension

Central Study Contacts

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

February 10, 2026

First Posted

February 23, 2026

Study Start

August 26, 2025

Primary Completion (Estimated)

December 1, 2027

Study Completion (Estimated)

December 1, 2028

Last Updated

February 24, 2026

Record last verified: 2026-02

Locations